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| HEPATIC FIBROSIS: PATHOGENESIS, DIAGNOSIS AND EMERGING THERAPIES, AN ISSUE OF CLINICS IN LIVER DISEASE, 12-4
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By
Scott Friedman
Included in series
The Clinics: Internal Medicine,
Description
Hepatic fibrosis is the final common pathway for a multitude of liver injuries. Viral-, immune-, or toxin-mediated liver injuries all
result in expansion of the extracellular matrix with distortion of hepatic architecture and development of cirrhosis. Originally thought
of as a one-way street, hepatic fibrosis now is recognized as a dynamic process with the potential for significant resolution. Authors
in this issue address the genetic determinants of fibrosis, oxidant stress, cellular contractility and vasoregulation, as well as relationships
between stellate cell activation, progenitor cells and hepatic regeneration. Current and future antifibrotic therapies are also discussed.
| Bibliographic details |
Hardbound, 240 pages, publication date: NOV-2008
ISBN-13: 978-1-4160-6315-5
ISBN-10: 1-4160-6315-3
Imprint: SAUNDERS
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041/407
Last update: 10 Sep 2009
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