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| FOLIC ACID AND FOLATES, 79
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Gerald Litwack, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA
Included in series
Vitamins and Hormones,
Audience
Researchers, faculty, and graduate students interested in cutting-edge review concerning the molecular and cellular biology of vitamins,
hormones, and related factors and co-factors. Libraries and laboratories at institutes with strong programs in cell biology, biochemistry,
molecular biology, gene regulation, hormone control, and signal transduction are likely to be interested.
Contents
1. Folate-Mediated One-Carbon Metabolism
Jennifer T. Fox and Patrick J. Stover
2. Mathematical Models of Folate-Mediated One-Carbon Metabolism
H. Frederik Nijhout, Michael C. Reed and C.M. Ulrich
3. Folate Deprivation, the Methionine Cycle and Alzheimer!|s Disease
Flaubert
Tchantchou and Thomas B. Shea
4. Benefits and Risks of Folic Acid Supplementation
Young-In Kim
5. Molecular Mechanisms of Adaptation
to Folate Deficiency
Ilan Ifergan and Yehuda G. Assaraf
6. Structure and Function of the Reduced Folate Carrier: A Paradigm of a Major
Facilitator Superfamily Mammalian Nutrient Transporter
Larry H. Matherly and Zhanjun Hou
7. Renal Conservation of Folates: Role of
Folate Transport Proteins
Vijaya L. Damaraju, Carol E. Cass and Michael B. Sawyer
8. Exploitation of the Folate Receptor in the Management
of Cancer and Inflammatory Disease
Christopher P. Leamon and Ann L. Jackman
9. Folate Receptor Expression in Pituitary Adenomas: Cellular
and Molecular Analysis
Chheng-Orn Evans, Congjun Yao, David Leborde and Nelson M. Oyesiku
10. Regulation of Human Dihydrofolate Reductase
Activity and Expression
Emine Ercikan Abali, Nancy E. Skacel, Hilal Celikkaya, Yi-Ching Hsieh
11. Catalysis of Methyl Group Transfers
Involving Tetrahydrofolate and B12
Stephen W. Ragsdale
12. Methyltetrahydrofolate in Folate-Binding Protein Glycine N-Methyltransferase
Zigmund Luka
13. Mechanism-Based Inhibitors of Folylpoly-??-glutamate Synthetase and ??-Glutamyl Hydrolase: Control of Folylpoly-??-glutamate
Homeostasis as a Drug Target
James K. Coward and John J. McGuire
14. Methylenetetrahydrofolate Reductase, Common Polymorphisms and Relation
to Disease
Philip Thomas and Michael Fenech
15. Mitochondrial Methylenetetrahydrofolate Dehydrogenase, Methenyltetrahydrofolate Cyclohydrolase
and Formyltetrahydrofolate Synthetases
Karen E. Christensen and Robert E. MacKenzie
16. The Structure and Mechanism of 6-Hydroxymethyl-7,8-dihydropterin
Pyrophosphokinase
Jeremy P. Derrick
| Bibliographic details |
Hardbound, 480 pages, publication date: OCT-2008
ISBN-13: 978-0-12-374232-2
Imprint: ACADEMIC PRESS
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Last update: 9 Nov 2009
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