Edited by
Lynne E. Maquat, University of Rochester, NY, USA
Cecilia Arraiano, Universidade Nova de Lisboa, Portugal
Description
Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding,
as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an
important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors,
and mRNA instability elements, responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated
processes involved in mRNA decay and its regulation.
Included in series
Methods in Enzymology
Audience:
Researchers in biochemistry, cell and molecular biology, genetics