Edited by
David Cheresh, The Scripps Research Institute, La Jolla, CA, USA
Description
Angiogenesis is the growth of new blood vessels and is an important natural process in the body. A healthy body maintains a perfect balance
of angiogenesis modulators. In many serious disease states, however, the body loses control over angiogenesis. Diseases that are angiogenesis-dependent
result when blood vessels either grow excessively or insufficiently. Understanding how angiogenesis "works" and how to control it, will
have massive implications on the management, treatments, and ultimately the prevention of many common (and not so common) diseases.
Angiogenesis cuts across virtually every discipline. The Angiogenesis Foundation identified angiogenesis as a "common denominator"
in our most serious diseases. Excessive angiogenesis occurs in diseases such as cancer, diabetic blindness, age-related macular degeneration,
rheumatoid arthritis, psoriasis, and many other conditions. Insufficient angiogenesis occurs in diseases such as coronary artery disease,
stroke, and delayed wound healing.
Included in series
Methods in Enzymology
Audience:
Researchers in biochemistry, cell and molecular biology, physiology, neurology, oncology, pathology, cardiology, rheumatology, opthamology
