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| ANGIOGENESIS: IN VIVO SYSTEMS, PART A, 444
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To order this title, and for more information, click here
Edited By
David Cheresh, The Scripps Research Institute, La Jolla, CA, USA
Included in series
Methods in Enzymology,
Description
Angiogenesis is the growth of new blood vessels and is an important natural process in the body. A healthy body maintains a perfect balance
of angiogenesis modulators. In many serious disease states, however, the body loses control over angiogenesis. Diseases that are angiogenesis-dependent
result when blood vessels either grow excessively or insufficiently. Understanding how angiogenesis "works" and how to control it, will
have massive implications on the management, treatments, and ultimately the prevention of many common (and not so common) diseases.
Angiogenesis cuts across virtually every discipline. The Angiogenesis Foundation identified angiogenesis as a "common denominator" in
our most serious diseases. Excessive angiogenesis occurs in diseases such as cancer, diabetic blindness, age-related macular degeneration,
rheumatoid arthritis, psoriasis, and many other conditions. Insufficient angiogenesis occurs in diseases such as coronary artery disease,
stroke, and delayed wound healing.
Audience
Researchers in biochemistry, cell and molecular biology, physiology, neurology, oncology, pathology, cardiology, rheumatology, opthamology
Contents
Isolation of natural angiogenesis inhibitors and their function; Chick CAM models; Ultrastructure analysis of blood vessels; Zebrafish
models; Lymphangiogenesis models and applications; Models of vascular permeability; Tumor models to study angiogenesis inhibitors; Studying
hemangiomas and vascular malformations; Ocular models of angiogenesis; Models of ischemia and ischemia/reperfusion; Vascular neural patterns;
Identification of important genes in vascular development; Imaging of tumor blood vessels; Imaging of blood vessels (in situ terminal
models); In vivo assays to screen anti-angiogenic agents; Blood vessel normalization; Patterning (neurons, ECM, EC) during angiogenesis,
vascular regression, inhibitors;
| Bibliographic details |
Hardbound, 400 pages, publication date: OCT-2008
ISBN-13: 978-0-12-374313-8
Imprint: ACADEMIC PRESS
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Last update: 20 Feb 2010
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