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| DYNAMICS OF BONE AND CARTILAGE METABOLISM
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Principles and Clinical Applications
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Second Edition
Edited By
Markus Seibel, Concord Hospital, University of Sydney, Australia
Simon Robins, Rowett Research Institute, Aberdeen, U.K.
John Bilezikian, Columbia University, New York, New York, U.S.A.
Description
This updated edition is a comprehensive treatise that spans the complete range of basic biochemistry of bone and cartilage components
to the clinical evaluation of disease markers in bone and joint disorders. With contributions from over 75 international experts, this
latest edition is indispensable reading for those involved in skeletal research as well as for rheumatologists, endocrinologists, clinical
biochemists, and other clinical disciplines participating in the management of patients with bone and cartilage diseases.
Audience
Endocrinologists, bone biologists, rheumatologists, clinical biochemists, and other clinical disciplines participating in the management of the patient with bone and cartilage diseases
Contents
Table of contents (in progress)
PART I
Components of the Organic Extracellular Matrix of Bone and Cartilage
CHAPTER 1
Structure, Biosynthesis
and Gene Regulation of Collagens in Cartilage and Bone
KLAUS VON DER MARK
CHAPTER 2
Fibrillogenesis and Maturation of Collagens
SIMON
P ROBINS
CHAPTER 3
Vitamin K Dependent Proteins of Bone and Cartilage
CAREN M GUNDBERG and SATORU K NISHIMOTO
CHAPTER 4
Non-collagenous
Proteins; Glycoproteins and Related Proteins
DICK HEINEG?RD, PILAR LORENZO and TORE SAXNE
CHAPTER 5
Proteoglycans and Glycosaminoglycans
TIM E HARDINGHAM
CHAPTER 6
Growth Factors
PHILIPPA A HULLEY, PETER I CROUCHER and GRAHAM G RUSSELL
CHAPTER 7
Prostaglandins and
Proinflammatory Cytokines
LAWRENCE G RAISZ and JOSEPH A LORENZO
CHAPTER 8
Integrins and Other Adhesion Molecules
MIEP H HELFRICH
and MICHAEL A HORTON
CHAPTER 9
Alkaline Phosphatases
JOSE LUIS MILLAN
Chapter 10
Acid Phosphatases
HELENA KAIJA, LILA OT PATRIKAINEN,
SARI L ALATALO, H KALERVO VAANANEN and PIRKKO T VIHKO
CHAPTER 11
Matrix Proteinases
IAN M CLARK and GILLIAN MURPHY
PART II
Structure
and Metabolism of the Extracellular Matrix of Bone and Cartilage
CHAPTER 12
Mineralization, Structure and Function of Bone
ADELE L BOSKEY
CHAPTER 13
Bone Structure and Strength
EGO SEEMAN
CHAPTER 14
The Cells of Bone
JANE B LIAN and GARY S STEIN
CHAPTER 15
Signalling
in bone
T JOHN MARTIN and NATALIE A SIMS
CHAPTER 16
Parathyroid Hormone: Structure, Function and Dynamic Actions
LORRAINE A FITZPATRICK
and JOHN P BILEZIKIAN
CHAPTER 17
Interaction of Parathyroid Hormone-Related Peptide with the Skeleton
DAVID GOLTZMAN
CHAPTER 18
The Vitamin D Hormone and Its Nuclear Receptor: Mechanisms Involved in Bone Biology
GEERT CARMELIET, ANNEMIEKE VERSTUYF, CHRISTA MAES,
GUY EELEN and ROGER BOUILLON
CHAPTER 19
Sex Steroid Effects on Bone Metabolism
DAVID G MONROE, THOMAS C SPELSBERG and SUNDEEP KHOSLA
CHAPTER 20
Physiology of Calcium and Phosphate Homeostasis
RENE RIZZOLI and JEAN-PHILIPPE BONJOUR
CHAPTER 21
The Central Control
of Bone Remodelling
PAUL A BALDOCK, SUSAN J ALLISON, HERBERT HERZOG and EDITH M GARDINER
CHAPTER 22
New Concepts in Bone Remodeling
DAVID W DEMPSTER and HUA ZHOU
CHAPTER 23
Products of Bone Collagen Metabolism
JUHA RISTELI and LEILA RISTELI
CHAPTER 24
Supramolecular
Structure of Cartilage Matrix
PETER BRUCKNER
CHAPTER 25
Products of Cartilage Metabolism
DANIEL-HENRI MANICOURT, JEAN-PIERRE DEVOGELAER
and EUGENE J-M A THONAR
CHAPTER 26
Fluid Dynamics of the Joint Space and Trafficking of Matrix Products
PETER A SIMKIN
CHAPTER 27
Transgenic
Models of Bone Disease
BARBARA E KREAM and JOHN R HARRISON
PART III
Markers of Bone and Cartilage Metabolism
Quantification: Technical
Aspects
CHAPTER 28
The Role of Genetic Variation in Osteoporosis
ANDRE G UITTERLINDEN, Joyce B J van Meurs, Fernando Rivadeneira, JOHANNES
P T M VAN LEEUWEN and HUIBERT A P POLS
CHAPTER 29
Measurement of Calcium, Phosphate and Magnesium
HEINRICH SCHMIDT-GAYK
Chapter
30
Measurement of Parathyroid Hormone
HARALD JUPPNER and GHADA EL-HAJJ FULEIHAN
Chapter 31
New Horizons for Assessment of Vitamin
D Status in Man
GARY L LENSMEYER, NEIL BINKLEY and MARC K. DREZNER
CHAPTER 32
Measurement of Biochemical Markers of Bone Formation
KIM E NAYLOR and RICHARD EASTELL
CHAPTER 33
Measurement of Biochemical Markers of Bone Resorption
MARIUS E KRAENZLIN and MARKUS
J SEIBEL
CHAPTER 34
Variability in the measurement of biochemical markers of bone turnover
TUAN V. NGUYEN, CHRISTIAN MEIER AND MARKUS
J. SEIBEL
CHAPTER 35
Validation of Biochemical Markers of Bone Turnover
KIM BRIXEN and ERIK F ERIKSEN
CHAPTER 36
Genetic Markers
of Joint Disease
MICHEL NEIDHART, RENATE E GAY and STEFFEN GAY
CHAPTER 37
Body Fluid Markers of Cartilage Metabolism
EUGENE J-M
A THONAR, MARY ELLEN LENZ, KOICHI MASUDA and DANIEL-HENRI MANICOURT
Clinical Applications
CHAPTER 38
Laboratory Assessment of Postmenopausal
Osteoporosis
PATRICK GARNERO and PIERRE D DELMAS
CHAPTER 39
Monitoring of Anabolic Treatment
JOHN P BILEZIKIAN and MISHAELA R RUBIN
CHAPTER 40
Monitoring of anti-resorptive treatment
CHRISTIAN MEIER, TUAN NGYEN and MARKUS J SEIBEL, Sydney, Australia
CHAPTER 41
Age-Related
Osteoporosis and Skeletal Markers of Bone Turnover
CLIFFORD J ROSEN
CHAPTER 42
Osteoporosis in Men
ERIC S. ORWOLL and JEAN-MARC
KAUFMAN
CHAPTER 43
Steroid-Induced Osteoporosis
IAN R REID
CHAPTER 44
Transplantation Osteoporosis: Biochemical Correlates of Pathogenesis
and Treatment
CAROLINA A MOREIRA KULAK and ELIZABETH SHANE
CHAPTER 45
Secondary Osteoporosis
JEAN E MULDER, CAROLINA A MOREIRA KULAK
and ELIZABETH SHANE
CHAPTER 46
Osteomalacia and Rickets
MARC K DREZNER
CHAPTER 47
Assessment of Bone and Joint Diseases: Renal
Osteodystrophy
ESTHER A GONZALEZ, ZIYAD AL ALY and KEVIN J MARTIN
CHAPTER 48
Primary Hyperparathyroidism
SHONNI J SILVERBERG and JOHN
P BILEZIKIAN
CHAPTER 49
Paget?s Disease of Bone
ANDREAS GRAUER, ETHEL SIRIS and STUART RALSTON
CHAPTER 50
Metastatic Bone Disease
JEAN-JACQUES BODY
CHAPTER 51
Rare Bone Diseases
MICHAEL P WHYTE
CHAPTER 52
Osteogenesis Imperfecta
FRANCIS H. GLORIEUX and FRANK
RAUCH
CHAPTER 53
Rheumatoid Arthritis and Other Inflammatory Joint Pathologies
STEVEN R GOLDRING and MARY B GOLDRING
CHAPTER 54
Osteoarthritis
and Degenerative Spine Pathologies
KRISTINA ?KESSON
| Bibliographic details |
Hardbound, 920 pages, publication date: JUL-2006
ISBN-13: 978-0-12-088562-6
ISBN-10: 0-12-088562-X
Imprint: ACADEMIC PRESS
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