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| FUNDAMENTALS OF PREPARATIVE AND NONLINEAR CHROMATOGRAPHY
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To order this title, and for more information, click here
Second Edition
By
Georges Guiochon, Department of Chemistry, University of Tennessee, Knoxville, TN, USA
Attila Felinger, Department of Analytical Chemistry University of Pecs, Pecs, Hungary
Dean G. Shirazi, Director of Analytical Development Laboratories, AAIPharma Wilmington, NC, USA
Description
The second edition of Fundamentals of Preparative and Nonlinear Chromatography is devoted to the fundamentals of a new
process of purification or extraction of chemicals or proteins widely used in the pharmaceutical industry and in preparative chromatography.
This process permits the preparation of extremely pure compounds satisfying the requests of the US Food and Drug Administration. The
book describes the fundamentals of thermodynamics, mass transfer kinetics, and flow through porous media that are relevant to chromatography.
It presents the models used in chromatography and their solutions, discusses the applications made, describes the different processes
used, their numerous applications, and the methods of optimization of the experimental conditions of this process.
Audience
Practitioners in the pharmaceutical industry, researchers and students in the chemical engineering and/or life sciences field
Contents
1. Introduction, Definitions, Goal.
2. The Mass Balance Equation of Chromatography and Its General Properties.
3. Single-Component
Equilibrium Isotherms.
4. Competitive Equilibrium Isotherms.
5. Transfer Phenomena in Chromatography.
6. Linear Chromatography.
7. Band Profiles of Single-Components with the Ideal Model.
8. Band Profiles of Two Components with the Ideal Model.
9.
Band Profiles in Displacement Chromatography with the Ideal Model.
10. Single--Component Profiles with the Equilibrium Dispersive
Model.
11. Two-Component Band Profiles with the Equilibrium-Dispersive Model.
12. Frontal Analysis, Displacement and the Equilibrium-Dispersive
Model.
13. System Peaks with the Equilibrium-Dispersive Model.
14. Kinetic Models and Single-Component Problems.
15.
Gradient Elution Chromatography under Nonlinear Conditions.
16. Kinetic Models and Multicomponent Problems.
17. Simulated
Moving Bed Chromatography.
18. Optimization of the Experimental Conditions.
| Bibliographic details |
Hardbound, 990 pages, publication date: FEB-2006
ISBN-13: 978-0-12-370537-2
ISBN-10: 0-12-370537-1
Imprint: ACADEMIC PRESS
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| Price and Ordering |
Price:
GBP 190
USD 290
EUR 223.95
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Last update: 10 Sep 2009
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