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| THE AUTOIMMUNE DISEASES
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Fourth Edition
Edited By
Noel Rose, The Johns Hopkins University, Baltimore, Maryland, U.S.A.
Ian Mackay, Monash University, Clayton, Victoria, Australia
Description
Since publication of the Third Edition in 1998, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease
has significantly deepened and broadened. This Fourth Edition incorporates new material and combines common themes underlying inductive
and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease
at genetic, molecular, cellular, and epidemiologic levels.
Audience
Basic and clinical scientists working in immunology, rheumatology and autoimmune diseases
Contents
IMMUNOLOGIC BASIS OF AUTOIMMUNITY
AUTOIMMUNITY: A HISTORY OF THE EARLY STRUGGLE FOR RECOGNITION
STRUCTURAL AND FUNCTIONAL
ASPECTS OF THE INNATE AND ADAPTIVE SYSTEMS OF IMMUNITY
GENERAL FEATURES OF THE AUTOIMMUNE DISEASES
ANTIGEN PRESENTATION, DENDRITIC CELLS
AND AUTOIMMUNITY
MHC COMPLEX AND AUTOIMMUNITY
T CELLS AND AUTOIMMUNITY
ROLE OF TH1 AND TH2 CELLS IN AUTOIMMUNITY
TOLERANCE AND AUTOIMMUNITY – T CELLS
REGULATORY T CELLS
PEPTIDE-BASED INSTRUCTION OF SUPPRESSOR COMMITMENT IN NAIVE T CELLS
B CELLS AND AUTOIMMUNITY
MEMORY B CELL
DEVELOPMENT
TOLERANCE AND AUTOIMMUNITY – B CELLS
GENERATION OF T CELL ANTIGENIC DETERMINANTS IN AUTOIMMUNITY AND THEIR RECOGNITION
APOPTOTIC
CELLS AS A SOURCE OF AUTOANTIGENS
EFFECTOR MECHANISMS OF AUTOIMMUNITY: ANTIBODIES, IMMUNE COMPLEXES
FUNCTIONAL EFFECTS OF ANTIBODIES
ADHESION MOLECULES AND CHEMOATTRACTANTS: RELEVANCE TO THE PATHOGENESIS AND TREATMENT OF AUTOIMMUNE DISEASES
SIGNALING PATHWAYS IN T AND
B LYMPHOCYTES
GENETICS AND AUTOIMMUNITY: ROLE OF HLA IN AUTOIMMUNE DISEASES
GENETICS AND AUTOIMMUNITY - NON-MHC
INFECTIONS, IMMUNITY
AND AUTOIMMUNITY
NON-INFECTIOUS ENVIRONMENTAL AGENTS AND AUTOIMMUNITY
VACCINES AND AUTOIMMUNE DISEASES
SEX, PREGNANCY AND AUTOIMMUNITY
MULTISYSTEM DISEASES
ANIMAL MODELS FOR AUTOIMMUNE DISEASE
SYSTEMIC LUPUS ERYTHEMATOSUS, CHRONIC CUTANEOUS LUPUS,
AND
MIXED CONNECTIVE TISSUE DISEASE
THE IMMUNOLOGY OF SYSTEMIC LUPUS ERYTHEMATOSUS
SYSTEMIC SCLEROSIS- SCLERODERMA
ANTIPHOSPHOLIPID SYNDROME
SJOGREN?S SYNDROME (AUTOIMMUNE EPITHELITIS)
RHEUM ATOID ARTHRITIS
SPONDYLOARTHRITIS AND CHRONIC IDIOPATHIC ARTHROPATHIES
POLYMYOSITIS
AND DERMATOMYOSITIS*
ENDOCRINE AND RELATED DISEASES
THYROID DISEASE
TYPE 1 DIABETES
ADRENALITIS
POLYENDOCRINE SYNDROMES
AUTOIMMUNE GASTRITIS AND PERNICIOUS ANEMIA
AUTOIMMUNE HYPOPHYSITIS
BLOOD DISEASES
AUTOIMMUNE HEMOLYTIC ANEMIA
AUTOIMMUNE
THROMBOCYTOPENIC PURPURA
AUTOIMMUNE NEUTROPENIA
ACQUIRED APLASTIC ANEMIA
CLOTTING DISORDERS
NEUROLOGIC DISEASES
MULTIPLE
SCLEROSIS
PERIPHERAL NEUROPATHIES
MYASTHENIA GRAVIS AND ANTI-RECEPTOR DISEASES OF THE NERVOUS SYSTEM
UVEITIS
INNER EAR DISEASE
INTESTINAL,
HEPATIC, AND PANCREATIC DISEASES
CELIAC DISEASE
INFLAMMATORY BOWEL DISEASES: ULCERATIVE COLITIS AND CROHN?S DISEASE
CHRONIC
HEPATITIS
PRIMARY BILIARY CIRRHOSIS
PRIMARY SCLEROSING CHOLANGITIS
AUTOIMMUNE PANCREATITIS
CUTANEOUS DISEASES
BULLOUS
SKIN DISEASES: PEMPHIGUS VULGARIS AND OTHER TYPES OF PEMPHIGUS
NON-BULLOUS SKIN DISEASES: ALOPECIA, PSORIASIS, VITILIGO, URTICARIA
UROGENITAL DISEASES
KIDNEY: GOODPASTURE?S DISEASE, LUPUS NEPHRITIS, ANCA-ASSOCIATED GLOMERULONEPHRITIS
AUTOIMMUNE ORCHITIS
AND MALE INFERTILITY
OOPHORITIS
CARDIOVASCULAR AND PULMONARY DISEASES
RHEUMATIC HEART DISEASE
MYOCARDITIS AND DILATED
CARDIOMYOPATHY
ATHEROSCLEROSIS: AUTOIMMUNITY TO HEAT-SHOCK PROTEINS
NECROTIZING ARTERITIS AND SMALL VESSEL VASCULITIS
VASCULITIS
IDIOPATHIC
BRONCHIOLITIS OBLITERANS, IDIOPATHIC PULMONARY FIBROSIS, AND THE AUTOIMMUNE DISORDERS OF THE LUNG
NEOPLASIA AND AUTOIMMUNITY
PARANEOPLASTIC DISEASES – AUTOIMMUNE RESPONSES TO TUMOR ANTIGENS
LYMPHOMA AND AUTOIMMUNE DISEASE
APOPTOSIS AND AUTOIMMUNITY -
LYMPHOPROLIFERATIVE
SYNDROMES
MISCELLANEOUS
CAMEOS
DIAGNOSIS, PREVENTION, AND THERAPY
AUTOANTIBODY ASSAYS, TESTING AND
STANDARDIZATION
T-CELL ASSAYS
PREDICTION OF AUTOIMMUNE DISEASE
THE PREVENTION OF AUTOIMMUNE DISEASE: TYPE 1 DIABETES AS A PARADIGM
EMERGING
THERAPIES IN AUTOIMMUNE DISEASES
EPILOGUE - ADVOCATUS DIABOLI
| Bibliographic details |
Hardbound, 1160 pages, publication date: MAR-2006
ISBN-13: 978-0-12-595961-2
ISBN-10: 0-12-595961-3
Imprint: ACADEMIC PRESS
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Price:
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USD 235
EUR 167.95
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Last update: 5 Sep 2009
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