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| IN VIVO CELLULAR AND MOLECULAR IMAGING, 70
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To order this title, and for more information, click here
Eric Ahrens, Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA, U.S.A.
Description
In recent times there has been an explosive expansion of new imaging methodologies that are capable of visualizing specific populations
of cells and molecular events in vivo. Vital imaging enhances our ability to study animal models of human development and disease,
such as cancers, cardiovascular disease, diabetes, and Alzheimer's. Furthermore, non-invasive imaging may ultimately be useful for monitoring
new generations of clinical molecular and cellular therapeutics, such as those utilizing viral vectors and stem cells. These new capabilities
have been facilitated by the development of new imaging probes or reagents that target specific cell types, are chemically responsive
to physiology, or are responsive to the presence of specific molecules, such as nucleic acids or enzymes.
This volume provides an introduction
to some of the most exciting methods and applications of emerging non-invasive imaging technologies using magnetic resonance imaging
(MRI), positron emission tomography (PET), and various biophotonic approaches. Highlighted, are recent developments in reagent design
that impart unique abilities to these imaging modalities to elucidate biological processes in vivo.
Audience
Developmental biologists, cell biologists, genetics researchers, and molecular biologists.
Contents
1. Magnetic Resonance Imaging: Utility as a Molecular Imaging Modality
2. MRI Contrast Agents in the Study of Development
3. 1H/19F Magnetic
Resonance Molecular Imaging with Perfluorocarbon Nanoparticles
4. Loss of cell ion homeostasis and cell viability in the brain: What
sodium MRI can tell us
5. Quantum dot surfaces for use in vivo and in vitro
6. In Vivo Cell Biology of Cancer Cells Visualized with Fluorescent
Proteins
7. Modulation of tracer accumulation in malignant tumors: gene expression, gene transfer and phage display
8. Amyloid Imaging:
From Bench-top to Bedside
9. In Vivo Imaging of Autoimmune Disease in Model Systems
| Bibliographic details |
Hardbound, 233 pages, publication date: NOV-2005
ISBN-13: 978-0-12-153170-6
ISBN-10: 0-12-153170-8
Imprint: ACADEMIC PRESS
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| Price and Ordering |
Price:
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EUR 131.95
USD 185
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Last update: 3 Oct 2009
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