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| DRUG DISCOVERY AND DEVELOPMENT
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Technology In Transition
To order this title, and for more information, click here
By
Humphrey Rang, MB, BS, MA, DPhil, FMedSci, FRS, Emeritus Professor of Pharmacology, University College, London, UK, formerly Director, Novartis Institute for Medical Science, London, UK
Description
This title is directed primarily toward health care professionals outside the United States. An ideal introduction to the pharmaceutical
industry, this book describes the process of bringing a new drug to the marketplace. It explains why, although thousands of compounds
show initial promise, only a small handful will be developed for human clinical trials and perhaps only one will become an approved drug.
Describing the huge complexities involved, it shows how new molecular understanding and techniques can make the process more targeted
and successful.
Contents
Section 1: Introduction:
Development of the pharmaceutical industry
Nature of disease and the purpose
of therapy
Therapeutic modalities
Section 2: Drug discovery
The drug discovery process:
General
principles and some case histories
Choosing the project
Choosing the target
The role of genomics and bioinformatics
High throughput screening
The role of chemistry in the drug discovery process
Pharmacokinetic issues in drug discovery
Pharmacology: its role in drug discovery
Biopharmaceuticals
Patent issues in drug discovery
Organisation
of a large drug discovery department
Section 3: Drug development:
Introduction
Assessing drug
safety
Pharmaceutical development
Clinical development
Protecting the assets: patenting and intellectual property
Regulatory affairs
Marketing the drug
Section 4: Facts and figures:
Drug discovery and
development: Facts and figures
| Bibliographic details |
Paperback, 360 pages, publication date: NOV-2005
ISBN-13: 978-0-443-06420-3
ISBN-10: 0-443-06420-2
Imprint: CHURCHILL LIVINGSTONE
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999/999
Last update: 10 Sep 2009
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