Search:

Product Information All Elsevier Sites   Advanced Product Search
SiteStat.jsp
THE IMMUNOASSAY HANDBOOK
The Immunoassay Handbook
To order this title, and for more information, click here
Third Edition

Edited By
David Wild, Director of Design Engineering, ConvaTec, Wound Care and Prevention, UK

Description
Immunoassays are biochemical tests that rely on antibodies (a special type of protein) to bind to specific molecular structures (antigens). They have become the most commercially successful technology in diagnostics, from home pregnancy testing kits to AIDS testing. Highly illustrated and clearly written, The Immunoassay Handbook provides an excellent guide to this fast-growing industry. Revised and updated, this third edition offers a balanced review of practical information and clinical applications in the field of immunoassay technology. Comprehensive and expertly written, The Immunoassay Handbook will be invaluable for a wide range of users from researchers developing immunoassay systems to developmental and marketing staff who need an excellent overview of how immunoassay principles, systems and applications work. With 68 chapters covering a wide range of topics, and new chapters looking at: surface plasmon resonance in kinetic, concentration and binding site analyses, and the foundations of immunochemistry, this handbook is a must read for all laboratory researchers and academics who use immunoassay as a tool including: pathologists, clinical and veterinary chemists, biochemists, students and researchers in immunology, biochemistry and medicine.

Audience
Laboratory researchers and academics who use immunossay as a tool including pathologists, clinical and veterinary chemists, biochemists, students and researchers in immunology, biochemistry and medicine.

Contents


Part 1 Principles
Chapter Headings.
Introduction to immunoassay principles (C. Davies).
Non-competitive immunoassays for small molecules - the anti-complex, selective antibody and apposition systems (C.H. Self et al.).
Ambient analyte assay (R. Ekins).
Free analyte immunoassay (N.D. Christofides).
The foundations of immunochemistry NEW (R.F. Ritchie).
Concepts (C. Davies).
Immunoassay development in the in vitro diagnostic industry (D. Brandt, S. Figard).
Antibodies (E. Liddell).
Standardization and calibration (D. Wild).
Separation Systems (D. Wild, W. Kusnezow).
Signal Generation and Detection Systems (Excluding Homogeneous Assays) (L.J. Kricka, D. Wild).
Homogeneous immunoassays (E.F. Ullman).
Calibration curve-fitting (B. Nix, D. Wild).
Conjugation methods (A.H. Dent).
Immunological biosensors (J.K. Gimzewski et al.).
Surface plasmon resonance in kinetic, concentration and binding site analyses (R. Karlsson et al.).
Lab-on-a-chip, micro-and nanoscale immunoassay systems (L.J. Kricka, D. Wild).



Part 2 Product Technology
Introduction to product technology in clinical diagnostic testing (D. Wild).
Market trends (D. Huckle, D. Wild).
Choosing an automated immunoassay system (L.J. Sokoll, D.W. Chan).
Automated system features (A. Truchaud et al.).
Over-the-counter pregnancy test kits (M.J. Wheeler).
Fluorescence microscopy: Microtrak (T. Houts).
Automated batch analyzers: IMx (K. Ford).
Automated bulk reagent random-access analyzers: UniCAP 100 (G. Evans, M. Rilv n).
Automated panel analyzers: PRISM (D. Shah, J. Stewart).
Unitized reagent random-access analyzers: IMMULITEReg and IMMULITE 1000 (A.L. Babson).
Bulk reagent random-access analyzers: ACS:180Reg SE (E. Gramignano).
Bulk reagent random-access analyzers: AxSYMReg (T. Donahoe).
Bulk reagent random access analyzers: ElecsysReg Immunoassay Systems (T. Atkinson).
Bulk reagent random-access analyzers: VitrosReg ECi (D. Wild).
Bulk reagent random-access analyzers: IMMULITEReg2000 and IMMULITE 2500 (A.L. Babson).
Bulk reagent random-access analyzers: ADVIA CentaurReg (L. Taylor, E. Gramignano).
Bulk reagent random-access analyzers: ARCHITECTReg i2000Reg and i2000SRReg analyzers (F.A. Quinn).
CEDIATM, a homogeneous enzyme immunoassay system (W.A. Coty, R. Loor).
Clinical Chemistry Analyzers: VITROSTMTM Immuno-Rate and MicroTipTM Assays (S.J. Danielson, D.A. Hilborn).
Near-patient tests: the TriageReg system (K.F. Buechler).
Near-patient tests: Stratus CS acute careTM diagnostic system (W.N. McLellan).
Over-the-counter tests: Clearblue pregnancy test , Clearblue ovulation test and Clearview (K. May).
Over-the-counter tests: Persona (K. May).



Part 3 Laboratory Management
Subject preparation, sample collection and handling (C. Wilde).
Laboratory quality assurance (P. Blockx, M. Martin).
Point-of-care testing (J.H. Nichols).
Troubleshooting guide (D. Wild).



Part 4 Applications
Thyroid (R. John et al.).
The Adrenal Cortex (S. Medbak).
Bone metabolism (K.W. Colston, J.C. Stevenson).
Infertility (M.J. Wheeler).
In vitro fertilization and embryo transfer (IVF-ET) (A.C. Olivar).
Hirsutism and virilization in the female (M.J. Wheeler).
Pregnancy (T. Chard).
Growth and growth hormone deficiency (M. Preece, J. Pringle).
Diabetes mellitus (P. Clark).
Hematology (D. Dawson et al.).
Cardiac markers (A.H.B. Wu).
Cancer markers (M.R. Suresh).
Allergy (L. Yman).
Autoimmune diseases (D.F. Keren M.D.).
Sexually transmitted diseases (B.J. Dille et al.).
Congenital diseases of microbiological origin (B.J. Dille et al.).
Hepatitis (I.K. Mushahwar).
Human retroviruses (G.J. Dawson, I.K. Mushahwar).
Dengue virus infections (B.J. Dille, I.K. Mushahwar).
Miscellaneous diseases of microbiological origin (B.J. Dille, I.K. Mushahwar).
Therapeutic Drug Monitoring (TDM) (P.A. Routledge, A.D. Hutchings).
Drugs of abuse (B. Widdop).
Assays for drug-screening applications and research (J.K. Horton et al.).
Immunoassay applications in veterinary diagnostics (E. Workman).

Bibliographic details
Hardbound, 930 pages, publication date: MAY-2005
ISBN-13: 978-0-08-044526-7
ISBN-10: 0-08-044526-8
Imprint: ELSEVIER

Price and Ordering
Price:
USD 250
GBP 167
EUR 196.95
order now
Books and book related electronic products are priced in US dollars (USD), euro (EUR), and Great Britain Pounds (GBP). USD prices apply to the Americas and Asia Pacific. EUR prices apply in Europe and the Middle East. GBP prices apply to the UK and all other countries.
See also information about conditions of sale & ordering procedures, and links to our regional sales offices.

030/302
Last update: 30 Nov 2009
Book contents
Table of contents
Reviews
Submit your review
Bookmark this page
Recommend this publication
Overview of all books
Printer-friendly version   Printer-friendly version