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 | T CELL SUBSETS, 83
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Cellular Selection, Commitment and Identity
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Frederick Alt, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA
H. Cantor, Dana Farber Cancer Institution, Boston, Massachussetts, U.S.A.
Laurie Glimcher, Harvard School of Public Health, Boston, Massachussetts, U.S.A.
Included in series
Advances in Immunology,
Description
This first thematic issue, of the Advances in Immunology series, highlights the remarkable new insights into the mechanisms
that govern development and function of T cell lineages. Recent developments in the understanding of the genetic and epigenetic mechanisms
that regulate development of the two major T cell lineages will have a fundamental impact on a number of research fields -immunology,
cell biology, hematology and stem cell research. All of these groups have a vested interest in comprehending issues such as stem cell
self renewal, progenitor plasticity, lineage commitment and cellular identity. Immunologists have a special interest in the mechanisms
that allow selection of a T cell repertoire whose members integrate genetic information for T cell receptor, co-receptor and specialized
immunologic function, since this process lies at the core of adaptive immunity.
T Cell Subsets is a timely and invaluable
review for immunologists, cell biologists hematologists and stem cell researchers
Audience
Immunologists and infectious disease researchers
Contents
Lineage Commitment and Developmental Plasticity in Early Lymphoid Progenitor Subsets
The CD4/CD8 Lineage Choice: New Insights into Epigenetic
Regulation During T Cell Development
CD4/CD8 Coreceptors in Thymocyte Development, Selection, and Lineage Commitment: Analysis of the
CD4/CD8 Lineage Decision
Development and Function of T Helper 1 Cells
Th2 cells: Orchestrating Barrier Immunity
Generation, Maintenance,
and Function of Memory T. Cells
An Integrated Model of Immunoregulation Mediated by Regulatory T Cell Subsets
| Bibliographic details |
Hardbound, 304 pages, publication date: MAY-2004
ISBN-13: 978-0-12-022483-8
ISBN-10: 0-12-022483-6
Imprint: ACADEMIC PRESS
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| Price and Ordering |
Price:
GBP 102.99 USD 170 EUR 121.95
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092/942
Last update: 3 Oct 2009
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