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 | THE QUINOLONES
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To order this title, and for more information, click here
Third Edition
By
Vincent Andriole, Yale University School of Medicine, New Haven, Connecticut, U.S.A.
Description
Quinolones constitute a large class of synthetic antimicrobial agents that are highly effective in the treatment of many types of infectious
diseases, particularly those caused by bacteria. New quinolones are continually being developed as bacterial species develop resistance
to existing quinolones. This book presents the most current information available in our continual struggle to conquer disease.
Over
time, bacteria become resistant to medicines that are used to combat them. Because of this, the medical world is always in search of
new and improved ways to battle these disease-causing bacteria. Quinolones are at the forefront of this research.
Edited by one of the
world's foremost authorities on the subject, the third edition of this highly successful title will serve as a valuable tool for primary
care physicians and researchers interested in a comprehensive, up-to-date reference on the chemistry, mechanisms of action, development
of resistance, and clinical efficacy of both currently available and newer quinolone compounds under investigation. This is the eagerly
anticipated fully revised edition of the standard reference in the field.
Audience
Graduate students, researchers, clinicians, and physicians in infectious disease, chemistry, and pharmacology. Also, pharmaceutical companies
researching and developing quinolone and antibacterial medicines.
Contents
Contributors.
Preface.
The Quinolones: History and Overview.
Chemistry and Mechanism of Action of the Quinolone Antibacterials.
Comparative
In-Vitro Properties of the Quinolones.
Bacterial Resistance to the Quinolones: Mechanisms and Clinical Implications.
Pharmacokinetics
and Pharmacodynamics of the Fluoroquinolones.
Use of Quinolones in Urinary Tract Infection and Prostatitis.
Use of the Quinolones in
Sexually Transmitted Diseases.
Treatment of Respiratory Infections with Quinolones.
Use of Quinolones in Surgery and Obstetrics and Gynecology.
Use of the Quinolones for Treatment and Prophylaxis of Bacterial Gastrointestinal Infections.
Use of the Quinolones in Treatment of Bacterial
Meningitis.
Use of the Quinolones in Immunocompromised Patients.
Use of the Quinolones in Skin and Skin Structure (Osteomyelitis) and
Other Infections.
Safety Overview: Toxicity, Adverse Effects, and Drug Interactions.
Use of the Quinolones in Pediatrics.
The Quinolones:
Prospects.
Index.
| Bibliographic details |
Hardbound, 517 pages, publication date: SEP-2000
ISBN-13: 978-0-12-059517-4
ISBN-10: 0-12-059517-6
Imprint: ACADEMIC PRESS
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| Price and Ordering |
Price:
USD 200 GBP 121 EUR 142.95
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Last update: 4 Sep 2009
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