By
Edwin Becker, National Institutes of Health, Bethesda, Maryland, U.S.A.
Description
High Resolution NMR provides a broad treatment of the principles and theory of nuclear magnetic resonance (NMR) as it
is used in the chemical sciences. It is written at an "intermediate" level, with mathematics used to augment, rather than replace, clear
verbal descriptions of the phenomena. The book is intended to allow a graduate student, advanced undergraduate, or researcher to understand
NMR at a fundamental level, and to see illustrations of the applications of NMR to the determination of the structure of small organic
molecules and macromolecules, including proteins. Emphasis is on the study of NMR in liquids, but the treatment also includes high resolution
NMR in the solid state and the principles of NMR imaging and localized spectroscopy.
Careful attention is given to developing and interrelating
four approaches - steady state energy levels, the rotating vector picture, the density matrix, and the product operator formalism. The
presentation is based on the assumption that the reader has an acquaintance with the general principles of quantum mechanics, but no
extensive background in quantum theory or proficiency in mathematics is required. Likewise, no previous background in NMR is assumed,
since the book begins with a description of the basic physics, together with a brief account of the historical development of the field.
This third edition of High Resolution NMR preserves the "conversational" approach of the previous editions that has been well accepted
as a teaching tool. However, more than half the material is new, and the remainder has been revised extensively. Problems are included
to reinforce concepts in the book.
Audience:
Professors and graduate students in physical and analytical chemistry and biochemistry; academic and industrial developers of analytical
instrumentation, and users of such instrumentation including researchers and technicians in chemistry, biotechnology, and biochemistry.