By
Georges Guiochon, Department of Chemistry, University of Tennessee, Knoxville, TN, USA
Bingchang Lin, Anshan Institute of Iron and Steel, Anshan, Lianing, People's Republic of China
Description
Nonlinear chromatography is a field that borders both chemical engineering and physical chemistry. In turn, the theory of nonlinear chromatography
is the foundation of preparative chromatography, a separation process that has lately become of considerable interest in the pharmaceutical
industry. Only chromatography is sufficiently flexible and powerful to satisfy the practical requirements encountered in most difficult
separations of pharmaceuticals and pharmaceutical intermediates.
Since "nonlinear" behaviour is strictly a mathematical concept,
it is difficult to leave mathematics out of any fundamental study of nonlinear chromatography. Therefore, this book will describe the
different mathematical models of chromatography, examine the assumptions on which they are based, consider their properties, and discuss
their solutions. All this will be done from a mathematical analysis point of view, paying considerable attention to the influence of
nonlinear behavior on the results.
Audience:
Graduate students in analytical and physical chemistry and in chemical engineering. Separation scientists and engineers in pharmaceutical companies and in manufacturers of fine chemicals.
