 |
|
| G PROTEIN PATHWAYS, PART A: RECEPTORS, 343
| |
| | |
|
|
To order this title, and for more information, click here
Ravi Iyengar, Mount Sinai School of Medicine, New York, U.S.A.
John Hildebrandt, Medical University of South Carolina, Charleston, U.S.A.
Description
G Protein Pathways is the first of three volumes examining the nature of heterotrimeric G proteins. The text takes an
integrated approach to studying common experimental questions at many different levels related to G proteins. Methods related to G proteins
using molecular modeling, systems biology, protein engineering, protein biochemistry, cell biology, and physiology are all accessible
in the same volume.
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is
one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently
consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains
much material still relevant today—truly an essential publication for researchers in all fields of life sciences.
Audience
Biochemists, molecular biologists, cell biologists, pharmacologists, neurophysiologists, neurochemists, neuroendocrinologists, and biomedical researchers.
Contents
Contributors to Volume 343.
Preface.
Volume in Series.
Section I. G Protein-Coupled Receptors.
A. Theoretical Evaluation of Receptor
Function:
Considerations in the Evaluation of Inverse Agonism and Protean Agonism at G Protein-Coupled Receptors,P. Chidiac.
Theoretical Implications of Receptor Coupling to Multiple G Proteins Based on Analysis of a Three-State Model,C. Scaramellini and
P. Leff.
B. Design and Use of Receptor Ligands:
Use of Retinal Analogues for the Study of Visual Pigment Function,
R.K. Crouch, V. Kefalov, W. Gartner, and M.C. Cornwall.
Design and Synthesis of Peptide Antagonists and Inverse Agonists for
G Protein-Coupled Receptors,S.M. Cowell, P.M. Balse-Srinivasan, J.M. Ahn, and V.J. Hruby.
Design of Peptide Agonists,V.J.
Hruby, R.S. Agnes, C. Cai.
Design of Nonpeptides from Peptide Ligands for Peptide Receptors,V.J. Hruby, W. Qiu, T. Okayama,
and V.A. Soloshonok.
Strategies for Mapping the Binding Site of the Serotonin 5-HT2A Receptor,B.J. Ebersole and S.C. Sealfon.
C. Structural Characterization of Receptor Proteins:
Use of the Substituted Cysteine Accessibility Method to Study
the Structure and Function of G Protein-Coupled Receptors,J.A. Javitch, L. Shi, and G. Liapakis.
Mass Spectrometric Analysis
of G Protein-Coupled Receptors,D.R. Knapp, R.K. Crouch, L.E. Ball, A.K. Gelasco, and Z. Ablonczy.
Probing the Higher Order
Structure of G protein-Coupled Receptors Using Tethered Cleavage Methods,A.K. Gelasco, R.K. Crouch, and D.R. Knapp.
Use of
Fluorescence Spectroscopy to Study Conformational Changes in the b2-Adrenoceptor,B.K. Kobilka and U. Gether.
Crystallization
of Membrane Protein in Cubo,P. Nollert, J. Navarro, and E.M. Landau.
N-Linked Carbohydrates on G Protein-Coupled Receptors:
Mapping Sites of Attachment and Determining Functional Roles,D.P. Davis and D.L. Segaloff.
Magic Angle Spinning Nuclear Magnetic
Resonance of Isotropically Labeled Rhodopsin,M. Eilers, W. Ying, P.J. Reeves, H.G. Khorana, and S.O. Smith.
Use of Nuclear
Magnetic Resonance to Study the Three-Dimensional Structure of Rhodopsin,P.L. Yeagle and A.D. Albert.
D. Design and
Use of Engineered Receptor Proteins:
Tools for Dissecting Signaling Pathways in Vivo: Receptors Activated Solely by
Synthetic Ligands,K. Scearce-Levie, P. Coward, C.H. Redfern, and B.R. Conklin.
Analysis of Structure-Function from Expression
of G Protein-Coupled Receptor Fragments,S.S. Karnik.
Construction and Analysis of Function of G Protein-Coupled Receptor-G
Protein Fusion Proteins,G. Milligan.
Synthetic Gene Technology: Applications to Ancestral Gene Reconstruction and Structure-Function
Studies of Receptors,B.S.W. Chang, M.A. Kazmi, and T.P. Kakmar.
Considerations in the Design and Use of Chimeric G Protein-Coupled
Receptor,J. Wess.
E. Molecular Modeling Studies of Receptor Structure and Function:
Strategies for Modeling
the Interactions of Transmembrane Helices of G Protein-Coupled Receptors by Geometric Complementarity Using the GRAMM Computer Algorithm,
I.A. Vakser and S. Jiang.
Three-Dimensional Representation of G Protein-Coupled Receptor Structures and Mechanisms,I. Visiers,
J.A. Ballesteros, and H. Weinstein.
F. Analysis of Receptor Protein Coupling:
Reconstitution of G Protein-Coupled
Receptors with Recombinant G Protein a and bg Subunits,W.E. McIntire, C.S. Myung, G. MacCleery, Q. Wang, and J.C. Garrison.
Cell-Free Membrane Desensitization Assay for G Protein-Coupled Receptors,M. Hunzicker-Dunn and L. Birnbaumer.
Methods to Determine
the Constitutive Activity of Histamine H2 Receptors,R. Leurs, M. Hoffman, A.E. Alewijnse, M.J. Smit, and H. Timmerman.
Expression
of G Protein-Coupled Receptors and G Proteins in Sf9 Cells: Analysis of Coupling by Radioligand Binding,R.T. Windh and D.R. Manning.
G Protein-Coupled Receptors and Proliferative Signaling,M.J. Smit, R.A. Bakker, and E.S. Burstein.
G. Characterization
of Receptor Heterogeneity:
Genetic Analysis of G Protein-Coupled Receptor Genes,D.P. Healy.
Identification of Adrenergic
Receptor Polymorphisms,K.M. Small, D.A. Rathz, and S.B. Liggett.
Strategies and Requirements for the Detection of RNA Editing
in G Protein Coupled-Receptor RNA,C.M. Niswender.
H. The Study of Receptor Trafficking:
Fluorescence Microscopy
Techniques for the Study of G Protein-Coupled Receptor Trafficking,L. Kallal and J.L. Benovic.
Measurement of Receptor Desensitization
and Internalization in Interact Cells,R.B. Clark and B.J. Knoll.
Morphological and Biochemical Strategies for Monitoring Trafficking
of Epitope-Tagged G Protein-Coupled Receptors in Agonist-Naive and Agonist-Occupied States,M. Wozniak, C. Saunders, N. Schramm,
J.R. Keefer, and L.E. Limbird.
Section II. Regulators of GPCR Function.
A. G Protein-Coupled Receptor Kinases (GRKs):
Characterization of G Protein-Coupled Receptor Kinases,A.N. Pronin, R.P. Loudon, and J.L. Benovic.
Regulation of G Protein-Coupled
Receptor Kinase 2,T. Haga, K. Haga, K. Kameyama, H. Tsuga, and N. Yoshida.
Rhodopsin and Its Kinase,I. Sokal, A. Pulvermuller,
J. Buczylko, K.P. Hofmann, and K. Palczewski.
B. Arrestins and Novel Proteins:
Characterization of Arrestin Expression
and Function,S.J. Mundell, M.J. Orsini, and J.L. Benovic.
Identification of Novel G Protein-Coupled Receptor-Interacting Proteins,
R.T. Premont and R.A. Hall.
Author Index.
Subject Index.
| Bibliographic details |
Hardbound, 680 pages, publication date: OCT-2001
ISBN-13: 978-0-12-182244-6
ISBN-10: 0-12-182244-3
Imprint: ACADEMIC PRESS
|
| Price and Ordering |
Price:
GBP 105.99
USD 175
EUR 124.95
|  |
Books and book related electronic products are priced in US dollars (USD), euro (EUR), and Great Britain Pounds (GBP). USD prices apply to the Americas and Asia Pacific. EUR prices apply in Europe and the Middle East. GBP prices apply to the UK and all other countries.
|
See also information about conditions of sale & ordering procedures, and links to our regional sales offices.
|
092/900
Last update: 3 Oct 2009
|
|
| |
| | |
|
|
| |
Home | Elsevier Sites | Privacy Policy | Terms and Conditions | Feedback | Site Map | A Reed Elsevier Company