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Edited By Angus Thomson, Departments of Surgery and Immunology, Thomas E. Starzl Transplantation Institute, University of Pittsburgh Schools of the Health Sciences, Pittsburgh, Pennsylvania, USA Michael Lotze, Departments of Surgery and Bioengineering, University of Pittsburgh Cancer Institute, University of Pittsburgh Schools of the Health Sciences, Pittsburgh, Pennsylvania, USA
Description The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate
immune responses.
Now expanded to two volumes, co-edited by Michael T Lotze, and written by over 120 international experts, the scope
of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual
cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine
gene transfer, antisense therapy and assay systems. This book is essential for researchers and clinicians interested in cytokines, including
anyone working in cancer biology, transplantation, infectious diseases, autoimmunity or bioinformatics.
Audience
Research level Immunologists, Pathologists, Cell and Cancer Biologists, Biochemists and Molecular Biologists. Clinicians and Clinical
Researchers. Also major market in Pharmaceutical and Biotech Industry. Very significant bulk sales potential. (NB Reachable with use
of BiomedSource)
Contents Volume 1
Preface
Foreward
Section I Basic Cytokine Biology
1 Cytokines Overview
2 Cytokine Genetics
3 The Phylogeny of Cytokines
4
Cytokine Signalling
Section II The Cytokines and Chemokines
Subsection A. The Hematopoietin Family Members
5 Growth Hormone and its
Receptors
6 Prolactin
7 Erythropoietin
8 Interleukin 2
9 Interleukin 3
10 Interleukin 4
11 Interleukin 5
12 Interleukin 6
13 Interleukin 7
14 Interleukin 9
15 Interleukin 11
16 Interleukin 12 Family: IL-12
17 Interleukin 13
18 Interleukin 15 and
Interleukin 21
19 Interleukin 16
20 Interleukin 17
21 Granulocyte-Macrophage
22 Granulocyte Colony-Stimulating Factor and its
Receptor
23 M-CSF Subsection B. The Interferon Family Members
24 Type I Interferons
25 Interferon-g
26 Interleukin 10
27 Interleukins
19, 20, 22, 24 and 26
Volume II.
Subsection C. The beta trefoil cytokines
28 Interleukin 1 a and b
29 Interleukin 1 Receptor Antagonist
30 Novel Interleukin-1 Homologues
31 Interleukin 18
32 The Fibroblast Growth Factors
33 The Hepatocyte Growth Factor The HGF Receptor,
MET
34 Toll-like Receptors: The Origins of Inflammation
35 Lymphotoxins
36 Tumor Necrosis Factor
37 TRAIL/apo2L
38 RANK-L : Receptor
Activator of NF-kB Ligan
39 CD95L/FasL its receptor CD95 (APO-1/Fas)
40 HMGB-1/Amphoterin
41 EGF Family Ligand
42 FLT3 Ligand
43 Stem
Cell Factor
44 Vascular Endothelial Growth Factor
45 Macrophage Migration Inhibitory Factor (MIF)46 Interleukin-8 and other CXC Chemokines
47 C-C Chemokines
48 Fractalkine-A Cell Surface Chemokines
49 Transforming Growth Factor b
50 Inhibin/Activin Family
51 Bone
Morphogenic Proteins
Section III. Clinical Application of Cytokines and Cytokine Inhibition
52 Autoimmunity and Cytokines: Pathogenesis
and Therapy
53 Cytokines and Cancer Caligiuri
54 Interferon alpha: biology, pharmacology, and therapy for chronic viral hepatitis
55
Haemopoietic Cytokines
56 Antiangiogenesis
57 Transplantation
58 Cytokines and Asthma
59 Cytokine Gene Transfer
60 Antisense Therapy
61 Assays for Cytokines
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