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Edited By
D.J. Rowlands, Division of Microbiology, School of Biochemistry and Molecular Biology, The Old Medical School, University of Leeds, UK
Description
Despite being caused by one of the smallest animal viruses, FMD is the most feared infection of domestic livestock; why is this so? There
are three main reasons: 1) its facility for rapid spread is tremendous - it is often quoted as being the most infectious disease agent
known; 2) its high morbidity - typically all members of a flock or herd of susceptible animals will become infected; 3) the loss of productivity
associated with infection is about 25% - an unsupportable financial burden in modern farming practice. Its destructive potential has
long been recognised and even in the 19th century considerable sums were invested in research into the nature and control of the disease.
Because of this initial support and its continuation through the intervening years FMDV research has scored some notable goals in the
advancement of fundamental virology. For example, it was the first animal disease to be shown to be caused by a virus, given the definition
of a virus as an agent that could not be removed by filtration procedures recognised to eliminate bacteria. This early crucial observation
has been followed by a string of milestone achievements in our understanding of the physical and biological nature of the virus and in
methods for its control.
This book summarises our current knowledge of FMD and FMDV, all of the authors who contributed to this volume
are key players in their specialist areas within the FMDV story. Some were heavily involved with the diagnosis and control that the outbreaks
of 2001 occasioned and the book benefits from including contributors with first hand experience of recent events.
Contents
Introduction. 1. Historical perspectives (F. Brown). 2. Molecular basis of pathogenesis (P.W. Mason et al.). 3. Structure and
receptor binding (T. Jackson et al.). 4. Evolution (E. Domingo et al.). 5. Molecular epidemiology (N. Knowles et
al.). 6. Vaccines (T. Doel). 7. Control and eradication (P. Sutmoller et al.). 8. Wildlife (G.R. Thomson et al.).
| Bibliographic details |
Paperback, 166 pages, publication date: JAN-2003
ISBN-13: 978-0-444-51302-1
ISBN-10: 0-444-51302-7
Imprint: ELSEVIER
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| Price and Ordering |
Price:
USD 79.95
EUR 67.95
GBP 50
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092/943
Last update: 4 Sep 2009
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