By
L.A. Kuhn
M.F. Thorpe
Description
The papers in this volume are from the workshop on
Protein Flexibility and Folding held in Traverse City, Michigan from
August 13 - 17, 2000. The purpose of the workshop was to bring together diverse people interested in protein folding and flexibility
from theoretical, computational and experimental perspectives and to encourage discussion on new approaches and challenges in the field.
The workshop was held in the Park Plaza Hotel with 43 participants, including 24 invited speakers. The small size of the group made for
easy exchanges, and many of the presentations by the invited speakers appear in this volume. There was also a very lively poster session.
The three-day workshop was organized so that the first day covered
Flexibility and Dynamics, the second day
Folding
and Unfolding, and the third day
Evolution and Design. This area of science is particularly appealing as it
spans a range of questions from very fundamental - as to how proteins fold in such short times with such reliability - to applications
such as the role of flexibility in screening for new ligands to a protein. Protein flexibility and folding have attracted the attention
of scientists from many disciplines, ranging from mathematics to molecular biology. The scientists at the workshop represented the breadth
of challenges in theory and applications that keep this field so fascinating and dynamic.
The present volume is organized along these
same lines.
Included in series
Biological Modeling
Audience:
For scientists interested in protein folding and flexibility from theoretical, computational and experimental perspectives, including
chemists involved in molecular modelling, molecular biologists, computational chemists, protein and polymer engineers and pharmaceutical
scientists.
