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| THE ONSET OF PUBERTY IN PERSPECTIVE
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 Invited papers of the 5th International Conference on the Control on the Onset of Puberty, Liège, Belgium, 26-28 September 1999
Edited by
J.-P. Bourguignon, Service de Pédiatrie Ambulatoire et Médecine de L'Adolescent, Centre Hospitalier Universitaire de Liège, Belgium
T.M. Plant, Department of Cell Biology & Physiology, School of Medicine, University of Pittsburgh, USA
Included in series
International Congress, 1202
Description
This volume presents the proceedings of the fifth in a series of meetings devoted to examining the mechanism of the onset of puberty.
It represents the most recent research data covering the major theme of the CNS and puberty, for example insights into the mechanism
relating CNS control centers and body messengers such as steroids, leptin and IGFs. This book presents important new findings such as
puberty and its disorders appearing to be developmentally regulated with critical pathophysiologic events occurring as early as in fetal
life. Particular emphasis is given to the neuroendocrinology of puberty, the interactions between neuronal glial cells, the dialogue
between body messengers and hypothalmic regulator centers and the development of a paradigm to study important neurobiological concepts
such as the mechanism of a chronobiological process.
The book employs a combined approach using basic science and clinical pediatric
endocrinology in an attempt to link animal and human physiology and pathology.
Audience
Perfect for basic neuroscientists and general, pediatric or reproductive endocrinologists
Contents
Ontogeny of GnRH neuron function.
Ontogeny of GnRH gene expression and secretion in primates
(T.M. Plant).
Departmental control
of gonadotropin releasing hormone (GnRH) gene expression: Role of pou homeodomain proteins
(M. Wierman et al.).
Modulation of
the GnRH gene and the onset of puberty
(A.C. Gore).
Ontogeny of GnRh neuron function - Integration
(O. Hirsch Pescovitz).
Growth,
growth factors and the onset of puberty.
Astrocyte-neuron signaling and the onset of female puberty
(S.R. Ojeda et al.).
The GH-N-IGF-I axis in sexual maturation: the rat paradigm
(V. d'Allèves, N.M. Gruaz-Gumowski, M.L. Aubert).
The GH-IGF-I axis
in sexual maturation: The monkey paradigm
(M.E. Wilson, K.J. Suter).
Early growth and the onset of puberty
(H.A. Delemarre-van de Waal et al.).
Puberty as a growth promoted event
(A.D. Rogol, J.N. Roemmich).
Growth factors and the onset of puberty - Integration
(M.O. Savage).
Neurosignalling and the onset of puberty.
Amino acid neurotransmission and early ontogeny of pulsatile GnRH
secretion from the rat hypothalamus
(J.P. Bourguignon et al.).
The control of the onset of puberty by neurotransmitters in female
rhesus monkeys
(E. Terasawa).
GABAA receptor regulation of mouse GnRH neurons over puberty
(A.E. Herbison, M.J. Skynner, J.A.
Sim).
Epilepsy and puberty
(P. Wolf).
Schizophrenia and peripubertal refinements in prefrontal cortical circuitry
(D.A. Lewis).
Neurosignalling
and the onset of puberty - Integration
(F.C.W. Wu).
Gonadal maturation and puberty.
Gonadotropin ligand and receptor mutations
in disorder of pituitary-gonadal function
(I.T. Huhtaniemi).
The role of puberty for testicular cancer
(E. Rajpert-De Meyts, N.E. Skakkebæk).
The role of puberty in ovarian disorders
(D. Apter, L. Dunkel).
Gonadal maturation and puberty - Integration
(I.A. Hughes).
Role
of sex steroids during development.
Fetal hypothalamic developmental events presage adult function
(J. Nilsen et al.).
Pubertal maturation in aromatase deficiency and resistance to estrogen
(M.M. Grumbach).
Sexual differentiation of the timing of sexual
maturation in sheep
(R.I. Wood et al.).
Precocious pubarche in girls may be a marker of a polyendocrinopathy
(L. Ibáñez,
N. Potau, F. de Zegher).
Role of sex steroids during development - Integration
(P.C. Sizonenko).
Leptin, NPY and the onset of puberty.
Hypothalamic pathways underlying leptin action
(J.K. Elmquist, C.F. Elias).
Leptin and NPY regulation of GnRH secretion and energy homeostasis
(S. P. Kalra et al.).
Leptin and neuropeptide Y stimulation of pulsatile GnRH secretion in vitro through distinct mechanisms
(M.C. Lebrethon et al.).
Leptin and NPY regulation of sexual maturation in the rat
(D.D. Pierroz et al.).
Leptin, neuropeptide
Y and puberty in non-human primates
(A. Sahu, T.M. Plant).
Human congenital leptin deficiency: the role of leptin in the onset of puberty
(I.S. Farooqi, S. O'Rahilly).
Leptin, neuropeptide-NPY and puberty - Integration
(P.E. Clayton).
Behavioural aspects of puberty.
The development of hypothalamic control of sexual behavior
(K. Wallen).
The role of sex hormones on the control of behavior during human
puberty
(H.E. Kulin et al.).
Puberty as a period of neural development and behavioral maturation - Integration
(C.L. Sisk).
Index of authors.
Subject index.
| Bibliographic details |
Hardbound, 430 pages, publication date: AUG-2000
ISBN-13: 978-0-444-50296-4
ISBN-10: 0-444-50296-3
Imprint: EXCERPTA MEDICA
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| Price and Ordering |
Price:
GBP 96.50
EUR 145
USD 145
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Last update: 26 Sep 2008
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