Description This report describes a revision of the model used in ICRP Publication 30 to calculate radiation doses to the respiratory tract of workers
resulting from the intake of airborne radionuclides. This revision was motivated by the availability of increased knowledge of the anatomy
and physiology of the respiratory tract and of the deposition, clearance, and biological effects of inhaled radioactive particles, and
by greatly expanded dosimetry requirements. To meet fully the needs of radiation protection, a dosimetric model for the respiratory tract
should: provide calculations of doses for individual members of the populations of all ethnic groups, in addition to workers; be useful
for predictive and assessment purposes as well as for deriving limits on intakes; account for the influence of smoking, air pollutants,
and respiratory tract diseases; provide for estimates of respiratory tract tissue doses from bioassay data; and be equally applicable
to radioactive gases as well as to particles.
In addition, large differences in radiation sensitivity among the respiratory tract
tissues and the doses they receive from inhaled radionuclides argue for calculating radiation doses to specific tissues of the respiratory
tract. To use these tissue doses effectively for radiation protection purposes, they must be compatible with the ICRP dosimetric system.
Addressing all of these requirements has resulted in a dosimetry model that is more complex than previous models. This complexity
is reflected in the structure of this report, which includes chapters on respiratory tract morphometry, physiology, and radiation biology
or health detriment. Other chapters deal with deposition and clearance of inhaled radioactive particles, inhalation of radioactive gases,
and application of the model to estimate respiratory tract doses. The model provides most of the flexibility needed to calculate doses
to the respiratory tract for a wide range of exposure conditions and for specific individuals. This flexibility also allows for revision
of reference parameter values as new information becomes available without changing the model. The wide availability of personal computers
allows for easy use of the model.
Audience
For regulatory and advisory agencies at regional, national and international levels; management bodies with responsibilities for radiological
protection; professional staff used as advisers; and individuals, such as radiologists, who have to make decisions about the use of ionising
radiation.
Contents Chapter headings:
Introduction. Morphometric model. Physiological parameters. Radiation biology considerations. Deposition model.
Gases and vapours. Clearance model. Dosimetry. Application of the model. Summary description of respiratory tract dosimetry model. References.
Annexe A - Anatomy and morphology of the respiratory tract. Annexe B - Respiratory physiology. Annexe C - Effects of radiation on the
respiratory tract. Annexe D - Deposition of inhaled particles. Annexe E - Clearance of particles from the respiratory tract. Annexe F
- Reference values for regional deposition. Annexe G - Specific absorbed fractions of photon energy. Annexe H - Absorbed fractions for
alpha, beta, positron, and electron emissions.
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