Description This volume provides an overview of the cytoskeleton particularly on the fundamental role the cytoskeleton plays in the regulation of
cell structure and function. This book represents new trends in cytoskeletal research that go beyond the traditional approach of identifying
new proteins in the cytoskeleton, but actually define how these proteins interact with signaling pathways. While the major emphasis in
this volume remains on the microfilament structure, some discussion has been included in this volume to illustrate the similarities and
differences between the three cytoskeletal elements namely the actin microfilament, the intermediate filaments and the microtubules.
Audience
Cell and molecular biologists working in the cytoskeletal field of research.
Contents The Cytoskeleton of the Platelet.
Membrane Cytoskeleton in Epithelial Cell.
The Connection between Actin ATPase and Polymerization.
Structure
and Function of Villin.
The connection between talin and focal adhesion protein.
Roles of the actin cytoskeleton and myosins in the endomembrane
system.
The BRG1 and the actin filament system.
The functional role of actin cytoskeleton dynamics and signaling.
Ionic waves propogation
along the dendritic cytoskeleton as a signaling mechanism.
Regulation of the Actin Cytoskeleton by Phospholipids.
Lipid interactions
of cytoskeletal proteins.
Spectrin function: A survey of genetic systems from Drosophila to humans.
Mechanisms of ion transport regulation
by microfilaments.
Embryo morphogenesis and the role of the actin cytoskeleton.
Domain-specific phosphorylation as a regulator of intermediate
filaments.
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