Edited by
Ferid Murad, University of Texas Medical School, Houston, U.S.A.
Series Editor:
J. August, John Hopkins University; Department of Pharmacology, Baltimore, Maryland, U.S.A.
M. Anders, University of Rochester; Department of Pharmacology, New York, U.S.A.
Description
This volume is dedicated to the topic of cyclic GMP. Chapters include discussions on the guanylyl cyclase and phosphodiesterase isoenzyme
families for cyclic GMP synthesis and hydrolysis, cyclic GMP-dependent protein kinases, and various hormones and ligands that regulate
cyclic GMP formation and/or metabolism. Several chapters also deal with some of the effects of cyclic GMP on other second messengers
such as calcium ion transport and smooth muscle relaxation. Some clinical studies with cyclic GMP and atrial natriuretic peptide are
also discussed. The last chapter raises many important questions in the field that remain to be addressed.
Included in series
Advances in Pharmacology