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| CELL SURFACE PROTEASES, 54
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Stanley Zucker, VA Medical Center, Northport, New York, U.S.A.
Wen-Tien Chen, State University of New York at Stony Brooks, New York, U.S.A.
Included in series
Current Topics in Developmental Biology,
Description
Cell Surface Proteases provides a comprehensive overview of these important enzymes that catalyze the hydrolysis of a
protein as it degrades to a simpler substance. In the 1990s, an explosion of new discoveries shed light on the role of cell surface proteases
and extended it beyond degradation of extracellular matrix components to include its influence on growth factors, cell signaling, and
other cellular events. This volume unites the scientific literature from across disciplines and teases out unified themes of interactions
between cell surface proteases and interconnecting cell surface-related systems -- including integrins and other adhesion molecules.
Scientists and students involved in developmental biology, cell biology and disease processes will find this an indispensable resource.
Audience
Developmental biologists, cell biologists, genetics researchers, and molecular biologists.
Contents
Membrane Type - Matrix Metalloproteinases
Surface Association of Secreted Matrix Metalloproteinases
Biochemical Properties and Functions
of Membrane-anchored Metalloprotease-Disintegrin Proteins (ADAMs)
Shedding of plasma membrane proteins
Expression of Meprins in Health
and Disease
Type II Transmembrane Serine Proteases
DPPIV, Seprase and Related Serine Peptidases in Multiple Cellular Functions
The
Secretases of Alzheimer's Disease
Plasminogen Activation at the Cell Surface
Cell Surface Cathepsin B: Understanding its Functional
Significance
Protease activated receptors
EMMPRIN (CD147), a cell surface regulator of Matrix Metalloproteinase Production and Function
The evolving roles of Cell Surface Proteases in Health and Disease: Implications for Developmental, Adaptive, Inflammatory and Neoplastic
Processes
Shed Membrane Vesicles and Clustering of Membrane-bound Proteolytic Enzymes
| Bibliographic details |
Hardbound, 452 pages, publication date: APR-2003
ISBN-13: 978-0-12-153154-6
ISBN-10: 0-12-153154-6
Imprint: ACADEMIC PRESS
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| Price and Ordering |
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EUR 131.95
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Last update: 30 Nov 2009
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