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| MATHEMATICAL MODELING IN EXPERIMENTAL NUTRITION: VITAMINS, PROTEINS, METHODS, 40
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To order this title, and for more information, click here
Stephen Coburn, Fort Wayne State Development Center, Indiana
Steve Taylor, University of Nebraska, Lincoln, USA
Douglas Townsend, Indiana University/Purdue University at Fort Wayne
Included in series
Advances in Food and Nutrition Research,
Description
This book developed from a series of conferences to facilitate the application of mathematical modeling to experimental nutrition. As
nutrition science moves from prevention of gross deficiencies to identifying requirements for optimum long term health, more sophisticated
methods of nutritional assessment will be needed. Collection and evaluation of kinetic data may be one such method.
This books opens
with chapters giving specific examples of the application of modeling techniques to vitamin A, carotenoids, folate, vitamin b-6, glycogen
phosphorylase, transthyretin, amino acids, and energy metabolism. Obtaining kinetic data on internal processes is a major challenge;
therefore, the text includes chapters on the use of microdialysis and ultrafiltration, use of membrane vesicles, and culture of mammary
tissue.
Many of the authors use the Simulation, Analysis and Modeling program which allows compartmental models to be described without
specifying the required differential equations. The final sections of the book, however, present some more mathematical descriptions
of physiological processes, including bioperiodicity, metabolic control, and membrane transport; discussions of some computational aspects
of modeling such as parameter distributions, linear integrators and identifiability; and alternative mathematical approaches such as
neural networks and graph theory.
Audience
Researchers and graduate students in food science and nutrition.
Contents
Vitamin Metabolism:
M.H. Green and J.B. Green, Quantitative and Conceptual Contributions of Mathematical Modeling
to Current Views on Vitamin A Metabolism, Biochemistry, and Nutrition. J.A. Novotny, L.A. Zech, H.C. Furr, S.R. Dieker, and A.J.
Clifford, Mathematical Modeling in Nutrition: Constructing a Physiologic Compartmental Model of the Dynamics of Beta-Carotene Metabolism. J.E. Swanson, K.J. Goodman, R.S. Parker, and Y.-y. Wang, Experimental Approaches to the Study of Beta-Carotene Metabolism: Potential
of a 13C Tracer Approach to Modeling Beta-Carotene Kinetics in Humans. J.F. Gregory, III, and K.C. Scott, Modeling of
Folate Metabolism. B.-F. Lin, J.-S. Kim, J.-C. Hsu, C. Osborne, K.Lowe, T. Garrow, and B. Shane, Molecular Biology in Nutrition
Research: Modeling of Folate Metabolism. S.P. Coburn, Modeling Vitamin B6 Metabolism.
Protein and Amino Acid Metabolism:
R.J. Beynon, C. Bartram, A. Flannery, R.P. Evershed,P. Hopkins, V. Toescu, J. Phoenix, and R.H.T. Edwards, Interrelationships
between Metabolism of Glycogen Phosphorylase and Pyridoxal Phosphate: Implications in McArdle's Disease. D. Hanes, L. Zech, J. Murrell,
and M.D. Benson, Metabolism of Normal and Met30 Transthyretin. M.J. Gahl, T.D. Crenshaw, N.J. Benevenga, and M.D. Finke,
Use of a Four Parameter Logistic Equation and Parameter Sharing to Evaluate Animal Responses to Graded Levels of Nitrogen or Amino Acids.
Energy Metabolism:
W.W. Wong, Total Energy Expenditure of Free-Living Humans Can Be Estimated with the Doubly Labeled
Water Method.
Methods for Obtaining Kinetic Data:
E.M. Janle and P.T. Kissinger, Microdialysis and Ultrafiltration. P. Proulx, Membrane Vesicles. J.D. Turner, A. Delaquis, and C. Malo, Culture of Mammary Tissue: Glucose Transport Processes.
Simulating Complex Metabolic Processes:
L.P. Mercer and D.S. Kelley, Analysis of Bioperiodicity in Physiological
Responses. A.R. Shultz, Nutrient?Response: A"Top Down"Approach to Metabolic Control. R.B. King, Modeling Membrane Transport.
Computational Aspects of Modeling:
W.F. Beltz, Estimation and Use of Kinetic Parameter Distribution in Metabolism
and Nutrition. R.C. Boston, T. McNabb, P.C. Greif, and L.A. Zech, Essential Numerical Supports for Kinetic Modeling Software:
Linear Integrators. J.A. Jacquez, Indentifiability. S.I. Sayegh, Dynamic Systems and Neural Networks: Modeling in Physiology
and Medicine. H. Zhang and Z. Zhang, Graph Theoretical Methods for Physiologically Based Modeling. Chapter References. Index
| Bibliographic details |
Hardbound, 362 pages, publication date: OCT-1996
ISBN-13: 978-0-12-016440-0
ISBN-10: 0-12-016440-X
Imprint: ACADEMIC PRESS
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USD 160
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Last update: 30 Nov 2009
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