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FETAL AND NEONATAL NEUROLOGY AND NEUROSURGERY
Fetal and Neonatal Neurology and Neurosurgery
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Fourth Edition

By
Malcolm Levene, MD, FRCP, FRCPCH, FMedSc, Professor of Pediatrics and Child Health, Division of Paediatrics and Child Health, University of Leeds, Leeds General Infirmary, Leeds, UK
Frank Chervenak, MD, FACOG, MMM, Given Foundation Professor and Chairman, Department of Obstetrics and Gynecology, New York Weill Cornell Medical Center, New York, NY, USA

Description
This book provides a definitive reference work on the developing brain, from conception through the first year of life. Its purpose is to provide the range of specialists involved in the management of the fetus and the neonate with the latest information on the developmental neurology and pathology of the developing central nervous system, so that they can provide prompt and informed treatment of neurological disability – the most feared complication of pregnancy and the early months of the life of the newborn child.

Audience
Specialists in fetal medicine, Neonatologists, General paediatricians, Paediatric neurosurgeons, Paediatric neurologists

Contents


SECTION I Structural Development of the CNS


1. The molecular basis of brain development
2. Early embryonic development of the brain
3. Development of consciousness: fetal, neonatal and maternal interactions
4. Ultrasound assessment of normal fetal brain development
5. MR imaging of the fetal central nervous system
6. Imaging the neonatal brain



SECTION II Functional Assessment of CNS Development


7. Functional assessment of the fetal CNS
8. The development of senses
9. Clinical assessment of the infant nervous system
10. Perinatal cerebral circulation
11. Cerebral blood flow and energy metabolism in the developing brain
12. EEG and evoked potentials in the neonatal period



SECTION III Anomalies


13. Congenital structural defects of the brain
14. Genetics of neurodevelopmental anomalies
15. Antenatal assessment of CNS anomalies, including neural tube defects
16. Transvaginal fetal neuroscan
17. Epidemiology and prevention of neural tube defects



SECTION IV Hemorrhagic and Ischemic Lesions


18. Fetal brain injury and multiple pregnancies
19. Infection, inflammation and brain injury
20. Neonatal intracranial hemorrhage
21. Cerebral ischemic lesions



SECTION V Perinatal Asphyxia


22. Pathophysiology of asphyxia
23. Antenatal prediction of asphyxia
24. Intrapartum monitoring for asphyxia
25. Prediction of asphyxia with fetal gas analysis
26. The asphyxiated newborn infant
27. Neuroprotection of the fetal and neonatal brain
28. Medico-legal issues: The United Kingdom perspective
29. Malpractice issues in perinatal medicine: The United States perspective



SECTION VI Infection of the CNS


30. Toxoplasmosis
31. Congenital viral infections and the central nervous system
32. Bacterial and fungal infections



SECTION VII Metabolic Disorders


33. Inborn errors of metabolism presenting with encephalopathy



SECTION VIII Seizure Disorders


34. Seizure disorders of the neonate
35. Hypoglycemia and brain injury - when neonatal metabolic adaptation fails
36. Kernicterus



SECTION IX the Special Senses


37. Disorders of vision
38. Hearing disorders



SECTION X Disorders of the Nerve and Muscle


39. Disorders of the spinal cord, cranial and peripheral nerves
40. Neuromuscular disorders



SECTION XI Hydrocephalus and Neurosurgery


41. Fetal neurosurgical interventions
42. Neonatal hydrocephalus – clinical assessment and non-surgical treatment
43. Neurosurgical management of hydrocephalus
44. Surgical management of neural tube defects
45. Congenital defects, vascular malformations and other lesions



SECTION XII Epidemiology of Neurologic Disability


46. The epidemiology of the cerebral palsies
47. The epidemiology of intellectual disabilities



SECTION XIII Ethical Dilemmas


48. Issues for the obstetrician
49. Issues for the neonatologist

Bibliographic details
Hardbound, 960 pages, publication date: JAN-2009
ISBN-13: 978-0-443-10407-7
ISBN-10: 0-443-10407-7
Imprint: CHURCHILL LIVINGSTONE


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Last update: 25 Nov 2009
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