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By
Lindsay Murray, MB, BS, FACEM, Emergency Physician and Clinical Toxicologist, Sir Charles Gairdner Hospital, Nedlands, Australia
Frank Daly, MBBS, FACEM, Director of Emergency Department and Consultant Clinical Toxicologist, Royal Perth Hospital; Clinical Senior Lecturer in
Emergency Medicine, University of Western Australia; Consultant Clinical Toxicologist, WA and NSW Poisons Information Centres, Australia
Mark Little, MBBS, DTM&H(Lond), FACEM, MPH&T, Consultant Emergency Physician and Clinical Toxicologist, Sir Charles Gairdner Hospital Perth; Clinical
Senior Lecturer in Emergency Medicine, University of Western Australia; Consultant Clinical Toxicologist, WA and NSW Poisons Information
Centres, Australia
Mike Cadogan, MA(Oxon), MBChB, FACEM, Consultant Emergency Physician, Sir Charles Gairdner Emergency Department, Clinical Senior Lecturer in Emergency Medicine, University of Western Australia, Australia
Description
The Toxicology Handbook provides an easily followed approach to the assessment and management of common, unusual and life-threatening
poisonings. Separate sections address envenoming problems specific to Australia, New Zealand and the South Pacific. This easy-to-use
handbook has a practical clinical focus and contains the authors' "Handy tips" and "Pitfalls" together with paediatric and pregnancy
considerations.
Audience
Emergency Medicine staff - physicians, trainees & nurses; rural & remote GPs and healthcare workers; RFDS
Contents
Chapter 1: Approach to the poisoned patient
1.1 Approach to the ?Poisoned Patient'
1.2 Resuscitation
1.3 Risk
Assessment
1.4 Supportive Care and Monitoring
1.5 Investigations
1.6 Gastrointestinal Decontamination
1.7 Enhanced Elimination
1.8
Antidotes
1.9 Disposition
Chapter 2: Specific considerations
2.1 Approach to Coma
2.2 Approach to Hypotension
2.3
Approach to Seizures
2.4 Agitated Delirium
2.5 Serotonin Syndrome
2.6 Anticholinergic Syndrome
2.7 Cholinergic Syndrome
2.8
Neuroleptic Malignant Syndrome
2.9 Alcohol Abuse, Dependence and Withdrawal
2.10 Sedative-Hypnotic Withdrawal
2.11 Opioid Withdrawal
2.12
Body Packers and Stuffers
2.13 Principles of Snakebite Management in Australia
2.14 Osmolality and Osmolar Gap
2.15 Approach
to Acid?Base Problems
2.16 The 12-lead ECG in Toxicology
2.17 Pregnancy and Lactation
2.18 Paediatric Considerations
2.19
Poisoning in the Elderly
Chapter 3: Toxic drugs
3.1 Alcohol: Ethanol
3.2 Alcohol: Ethylene glycol
3.3
Alcohol: Isopropylalcohol
3.4 Alcohol: Methanol
3.5 Alcohols: Other Toxic Alcohols
3.6 Amiodarone
3.7 Amisulpride
3.8
Amphetamines
3.9 Angiotensin Converting Enzyme (ACE) Inhibitors
3.10 Anticoagulant Rodenticides
3.11 Antihistamines: Non-Sedating
3.12
Antihistamines: Sedating
3.13 Arsenic
3.14 Beta-Blockers
3.15 Baclofen
3.16 Benzodiazepines
3.17 Benztropine
3.18 Bupropion
3.19
Calcium Channel Blockers (CCBs)
3.20 Cannabinoids (Marijuana)
3.21 Carbamazepine
3.22 Carbon Monoxide
3.23 Chloroquine
3.24
Clonidine
3.25 Clozapine
3.26 Cocaine
3.27 Colchicine
3.28 Corrosives
3.29 Cyanide
3.30 Digoxin: Acute Overdose
3.31
Digoxin: Chronic Poisoning
3.32 Diphenoxylate – Atropine
3.33 Gamma-hydroxybutyrate (GHB)
3.34 Glyphosate
3.35 Hydrocarbons
3.36
Hydrofluoric Acid
3.37 Insulin
3.38 Iron
3.39 Isoniazid
3.40 Lead
3.41 Lithium: Acute Overdose
3.42 Lithium Chronic
Toxicity
3.43 Monoamine Oxidase (MAO) Inhibitors
3.44 Mercury
3.45 Metformin
3.46 Methotrexate
3.47 Mirtazapine
3.48
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
3.49 Olanzapine
3.50 Opioids
3.51 Organochlorines
3.52 Organophosphorous Agents
3.53
Paracetamol: Acute Overdose
3.54 Paracetamol: Repeated Supratherapeutic Ingestion
3.55 Paraquat
3.56 Phenothiazines and Butyrophenones
3.57
Phenytoin
3.58 Potassium Chloride
3.59 Quetiapine
3.60 Risperidone
3.61 Salicylates
3.62 Selective Serotonin Re-uptake
Inhibitors (SSRIs)
3.63 Strychnine
3.64 Sulphonylureas
3.65 Tricyclic Antidepressants (TCAs)
3.66 Theophylline
3.67 Thyroxine
3.68
Valproic acid (Sodium Valproate)
3.69 Venlafaxine
3.70 Warfarin
Chapter 4: Antidotes
4.1 Atropine
4.2
Calcium
4.3 Cyproheptadine
4.4 Desferrioxamine
4.5 Dicobalt Edetate
4.6 Digoxin Immune Fab
4.7 Dimercaprol (British Antilewisite)
4.8
Ethanol
4.9 Flumazenil
4.10 Folinic acid
4.11 Fomepizole
4.12 Glucagon
4.13 Glucose
4.14 Hydroxocobalamin
4.15 Insulin?Dextrose
Euglycaemia
4.16 Methylene Blue
4.17 N-Acetylcysteine
4.18 Naloxone
4.19 Octreotide
4.20 Penicillamine
4.21 Physostigmine
4.22
Pralidoxime
4.23 Pyridoxine
4.24 Sodium Bicarbonate
4.25 Sodium Calcium Edetate (EDTA)
4.26 Sodium Thiosulfate
4.27 Succimer
4.28
Vitamin K
Chapter 5: Envenomings
5.1 Snake: Black
5.2 Snake: Brown
5.3 Snake: Death Adder
5.4 Snake:
Tiger
5.5 Snake: Taipan
5.6 Snake: Sea Snakes
5.7 Australian Scorpions
5.8 Marine Envenoming: Bluebottle Jellyfish
5.9
Marine Envenoming: Stonefish
5.10 Marine Envenoming: Box Jellyfish
5.11 Marine Envenoming: Irukandji Syndrome
5.12 Marine Envenoming:
Blue-Ringed Octopus
5.13 Spider: Redback
5.14 Spider: Funnel-Web (Big Black)
5.15 Spider: White-Tailed
Chapter
6: Antivenom
6.1 CSL Black Snake Monovalent Antivenom
6.2 CSL Brown Snake Monovalent Antivenom
6.3 CSL Death Adder
Monovalent Antivenom Snake
6.4 CSL Tiger Snake Monovalent Antivenom Snake
6.5 CSL Taipan Snake Monovalent Antivenom Snake
6.6
CSL Sea Snake Antivenom
6.7 CSL Polyvalent Snake Antivenom
6.8 CSL Stonefish Antivenom
6.9 CSL Box Jellyfish Antivenom
6.10
CSL Redback Spider Antivenom
6.11 CSL Funnel-Web Spider Antivenom
Appendices
Appendix 1: PIC Numbers and
Other Countries
Appendix 2: Example ECGs (1 page per ECG)
Appendix 3: Drug Concentrations and Conversion Charts
Appendix 4:
Alcohol Pathways
Appendix 5: Nomograms
- Methotrexate
- Paracetamol
- Paraquat
Appendix 6: Therapeutic Over-warfarinisation
Appendix
7: Management of Allergic Reactions to Antivenoms
| Bibliographic details |
Paperback, 480 pages, publication date: DEC-2006
ISBN-13: 978-0-7295-3789-6
ISBN-10: 0-7295-3789-7
Imprint: CHURCHILL LIVINGSTONE
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042/408
Last update: 30 Nov 2009
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