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FUNDAMENTALS OF MOLECULAR DIAGNOSTICS
Fundamentals of Molecular Diagnostics
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By
David Bruns, MD, Professor of Pathology, Director of Clinical Chemistry and Associate Director of Molecular Diagnostics, University of Virginia, Charlottesville, VA, and Editor, Clinical Chemistry, Washington, DC
Edward Ashwood, MD, Professor of Pathology, University of Utah, and Laboratory Director, ARUP Laboratories, Salt Lake City, UT
Carl Burtis, PhD, Chief, Clinical Chemistry, Health Division, Oak Ridge National Laboratory, Oak Ridge, TN, and Clinical Professor of Pathology, University of Utah School of Medicine, Salt Lake City, UT

Description
This book offers an introduction to the newest, fastest-growing field in laboratory science. Explaining and clarifying the molecular techniques used in diagnostic testing, this text provides both entry-level and advanced information. It covers the principles of molecular biology along with genomes and nucleic acid alterations, techniques and instrumentation, and applications of molecular diagnostics. Written by leading experts, this book includes illustrations, tables, and a colorful design to make information easy to find and easy to use.

Contents


I. Principles


1. Principles of Molecular Biology

2. Genomes and Nucleic Acid Alterations



II. Techniques and Instrumentation


3. Specimen Collection and Processing

4. Nucleic Acid Isolation

5. Nucleic Acid Techniques

6. Miniaturization: DNA Chips and Devices

7. Design and Operation of a Molecular Diagnostics Laboratory

8. Introduction to Evidence-Based Molecular Diagnostics



III. Applications


9. Inherited Diseases

10. Identity Assessment

11. Molecular Methods in Diagnosis and Monitoring of Infectious Diseases

12. Pharmacogenetics

13. Molecular Genetics in Diagnosis of Human Cancers



IV. Appendix


14. Reference Information

Answers to Review Questions

Glossary

Bibliographic details
Hardbound, 288 pages, publication date: MAY-2007
ISBN-13: 978-1-4160-3737-8
ISBN-10: 1-4160-3737-3
Imprint: SAUNDERS


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Last update: 25 Nov 2009
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