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| CAVEOLAE AND LIPID RAFTS : ROLES IN SIGNAL TRANSDUCTION & THE PATHOGENESIS OF HUMAN DISEASE, 36
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Advances in Molecular and Cell Biology
To order this title, and for more information, click here
Edited By
Edward Bittar, Department of Physiology, University of Wisconsin Medical School, Madison, USA
Philippe Frank
Michael Lisanti
Included in series
Advances in Molecular and Cell Biology,
Description
Caveolae (latin for little caves) are small structures found at the surface of cells. They are responsible for the regulation of important
metabolic pathway. As a consequence, they may play a critical role in several human diseases such as atherosclerosis, cancer, diabetes,
and muscular dystrophies. This book analyzes the role and function of caveolae in these aspects and serves as the first textbook currently
available on caveolae/caveolin.
Audience
Cell biologists, pharmaceutical researchers, and graduate level and medical students.
Contents
Section 1: Caveolae organization and role in lipid cholesterol metabolism.
Lipid rafts and caveolae organization.
Caveolae and the regulation
of cellular cholesterol homeostasis.
Section 2: Caveolae and the regulation of endocytosis.
The Caveolae Internalization Machinery.
Lipid
raft mediated entry of bacteria into host cells.
Section 3: Examples of the role of caveolins in cell signaling.
The caveolin interaction
with the endothelial nitric oxide synthase (eNOS).
Caveolae and Estrogen Receptor Signaling.
eNOS regulation by sphingosine 1-phosphate
and caveolin.
Insulin signaling and caveolae.
Section 4: Caveolae and pathologies.
Caveolin-3, Caveolae, and Hereditary Muscle Diseases.
Caveolae and Caveolins in the Vascular System.
Caveolin Proteins in Cardio-pulmonary Disease and Lung Cancers.
| Bibliographic details |
Hardbound, 264 pages, publication date: JUL-2005
ISBN-13: 978-0-444-51500-1
ISBN-10: 0-444-51500-3
Imprint: ELSEVIER
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| Price and Ordering |
Price:
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USD 169.95
EUR 129.95
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Last update: 3 Oct 2009
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