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| NON-NEURONAL CELLS OF THE NERVOUS SYSTEM: FUNCTION AND DYSFUNCTION, 31
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Part I: Structure, Organization, Development and Regeneration
Part II: Biochemistry, Physiology and Pharmacology
Part III: Pathological Conditions
To order this title, and for more information, click here
By
L. Hertz, Gilmour, Ontario, Canada
Included in series
Advances in Molecular and Cell Biology, 31
Description
The brain, and the rest of the nervous system, consists of nerve cells (neurons) and non-neuronal cells (glial cells), which by far outnumber
the neurons, but in the past have received much less attention.
This began to change about 30 years ago with the realization that
glial cells carry out very important functions, generally in collaboration with the nerve cells. Evidence is now starting to accumulate
that glial cells, especially astrocytes and microglia, may be major (in some cases the main) players in a multitude of neurological and
mental diseases, and that different types of glial cells interact not only with nerve cells but also with each other and with cells lining
brain tissue and controlling exchange of nutrients and other compounds between the brain and the rest of the body. Understanding of these
interactions during normal function and in disease states is hampered by the fact that general knowledge of cellular interactions during
brain function is limited.
These books present an attempt to remedy this situation. In the first two volumes, basic information
about cell types and biochemical and physiological interactions between these cells is provided by leading experts in the field, and
in the last part emerging evidence of the importance of such cellular interactions in several of the most important neurological and
mental diseases is presented by leading researchers working actively in the field in question.
Contents
Part I. Structure, Organization and Development.
1. Cytoarchitectonics of non-neuronal cells in the nervous system (J.R.
Wolff. T.I. Chao). 2. Oligodendrocyte phenotypical and morphological heterogeneity: a reexamination of old concepts in view of new findings
(S. Szuchet, M.A. Seeger). 3. Regulation of cell cycle progression in astrocytes (Y. Naktsuji, R.H. Miller).
4. Role of neuron-glia
interactions (F.C. Alcantara Gomes, S.K. Rehen). 5. Cells lining the ventricular system: evolving concepts underlying developmental events
in the embryo and adult (F.G. Szele, S. Szuchet). 6. The perisynaptic astrocyte process as a glial compartment - immunolabelling for
glutamine synthetase and other glial markers (A. Derouiche). 7. The astrocytic syncytium (E. Scemes, D.C. Spray). 8. Structural plasticity
of non-neuronal cells in the hypothalamo-neurohypophyseal system: in the right place at the right time (A.K. Salm, A.E. Ayoub, B.E. Lally).
9. Glial-neuronal-endothelial interactions and the neuroendocrine control of GnRH secretion (V. Prévot, S. De Serrano, C. Estrella).
10. Meninges and perivasculature as mediators of CNS plasticity (F. Mercier, G.I. Hatton). 11. Mechanisms of infiltration of immune cells,
bacteria and viruses through brain endothelium (P.O. Couraud, X. Nassif, S. Bourdolos). 12. Hydrocephalus disorders: their biophysical
and neuroendocrine impact on the choroids plexus epithelium (C.E. Weaver, J.A. Duncan et al.). 13. Schwann cell interactions
with axons and CNS glial cells during optic nerve regeneration (M. Dezawa).
14. Control of microglial activity by protective autoimmunity
(M. Schwartz). 15. Roles of retinal macroglia in maintaining the stability of the retina (J. Stone, K. Valter). 16. Function and dysfunction
of enteric glia (T.C. Savidge, J. Cabarrocas, R.S. Liblau).
Part II. Biochemistry, Physiology and Pharmacology.
1. A
role of lactate released from astrocytes in energy production during neural activity? (E.L. Roberts Jr., C.P. Chih). 2. Principles of
the measurement of neuroglial metabolism using in vivo 13C spectroscopy (R. Gruetter). 3. Ion, transmitter and drug effect
on energy metabolism in astrocytes (L. Hertz, L. Peng et al.).
4. Role of astrocytes in homeostatis of glutamate and GABA during
physiological pathophysiological conditions (A. Schousboe, H.S. Waagepetersen). 5. Contributions of astrocytes to ischemia-induced neuronal
dysfunction in vivo (A. Haberg, U. Sonnewald).
6. Differential vulnerability of oligodendrocytes and astrocytes to hypoxic-ischemic
stresses (H. Marrif, B.H.J. Juurlink). 7. Astrocytic receptors and second messenger systems (E. Hansson, L. Rönnbäck). 8. Transactivation
in astrocytes as a novel approach for neuroprotection (L. Pengj). 9. Role of glial cells in cholesterol homeostasis in the brain (J.L.
Ito, S. Yokoyama). 10. Non-neuronal cells in the nervous system: sources and targets of neuroactive steroids (R.C. Melcangi, I. Azcoitia et al.). 11. Expression of neurotrophic factors and cytokines and their receptors on astrocytes in vivo (T. Nakagawa, J.P. Schwartz).
12. The nitric oxide/cyclic GMP pathway in CNS glial cells (A. Garcia, M.A. Baltrons). 13. Potassium homeostasis in the brain at the
organ and cell level (W. Walz). 14. Potassium and glia-derived slow potential shifts in relation to behaviour (P. Laming). 15. Regulation
of Ca2+ stores in glial cells (G. Scapagnini, T.J. Nelson, D.L. Alkon). 16. Decoding calcium wave signaling (A.H. Cornell-Bell,
P. Jung, V. Trinkaus-Randall). 17. Mathematical modeling of intracellular and intercellular calcium signaling (J.W. Shuai, S. Nadkarni,
P. Jung). 18. pH regulation in non-neuronal brain cells and interstitial fluid (M.O. Bevensee, S.D. McAlear). 19. AVP effects and water
channels in non-neuronal CNS cells (Y. Chen, M. Spatz).
Part III. Pathological Conditions.
1. Alexander disease: a primary
disease of astrocytes (L.F. Eng, Y.L. Lee). 2. Glil reaction and reactive glia (M. Kalman). 3. Glial heme oxygenase-1 in CNS injury
and disease (H. Schipper). 4. Astrocytes and microglia in Alzheimer's disease (S.W. Barger).
5. Non-neuronal cells interactions in HIV-1-associated
dementia (A. Ghorpade, H.E. Gendelman). 6. Glycoprotein gp 120-mediated astrocytic dysfunction (E.Z. Kovacs, B.A. Bush, D.J. Benos).
7. The role of astrocytes and microglia im persistent pain (V. Raghavendra, J.A. DeLeo). 8. Pathogenic role of glial cells in Parkinson's
disease (S. Przedborski, J.E. Goldman). 9. Upregulation of peripheral-type (mitochdrial) benzodiazepine receptors in hyperammonemic syndromes:
consequences for neuronal excitability (M. Bélanger, S. Ahboucha et al.).
10. Role of the cytokine network in major
psychoses (N. Müller, M.J. Schwarz). 11. Shared effects of all three conventional anti-bipolar drugs on the phosphoinositide system
in astrocytes (L. Hertz, Y. Chen et al.). 12. Glial cell loss in mood disorders and schizophrenia (L. Price). 13. Non-neuronal
cells in the nervous system: function and dysfunction (P. Werner, E. Brand-Schieber, C.S. Raine). 14. Role of glia in Prion disease (D.R.
Brown, J. Sassoon). 15. Schwann cells in diabetic neuropathy (A.P. Mizisin). 16. Müller cells in retinopathies (A. Bringmann, M.
Francke, A. Reichenbach).
| Bibliographic details |
Hardbound, 1300 pages, publication date: DEC-2003
ISBN-13: 978-0-444-51451-6
ISBN-10: 0-444-51451-1
Imprint: ELSEVIER
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GBP 308.99
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Last update: 30 Nov 2009
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