By
L. Hertz, Gilmour, Ontario, Canada
Description
The brain, and the rest of the nervous system, consists of nerve cells (neurons) and non-neuronal cells (glial cells), which by far outnumber
the neurons, but in the past have received much less attention.
This began to change about 30 years ago with the realization that
glial cells carry out very important functions, generally in collaboration with the nerve cells. Evidence is now starting to accumulate
that glial cells, especially astrocytes and microglia, may be major (in some cases the main) players in a multitude of neurological and
mental diseases, and that different types of glial cells interact not only with nerve cells but also with each other and with cells lining
brain tissue and controlling exchange of nutrients and other compounds between the brain and the rest of the body. Understanding of these
interactions during normal function and in disease states is hampered by the fact that general knowledge of cellular interactions during
brain function is limited.
These books present an attempt to remedy this situation. In the first two volumes, basic information
about cell types and biochemical and physiological interactions between these cells is provided by leading experts in the field, and
in the last part emerging evidence of the importance of such cellular interactions in several of the most important neurological and
mental diseases is presented by leading researchers working actively in the field in question.
Included in series
Advances in Molecular and Cell Biology
