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| THE HLA FACTSBOOK
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To order this title, and for more information, click here
By
Steven Marsh, Anthony Nolan Research Institute, London, U.K.
Peter Parham, Stanford University School of Medicine, Palo Alto, California, U.S.A.
Linda Barber, Anthony Nolan Research Institute, London, U.K.
Description
The HLA FactsBook presents up-to-date and comprehensive information on the HLA genes in a manner that is accessible to both beginner
and expert alike. The focus of the book is on the polymorphic HLA genes (HLA-A, B, C, DP, DQ, and DR) that are typed for in clinical
HLA laboratories. Each gene has a dedicated section in which individual entries describe the structure, functions, and population distribution
of groups of related allotypes. Fourteen introductory chapters provide a beginner's guide to the basic structure, function, and genetics
of the HLA genes, as well as to the nomenclature and methods used for HLA typing. This book will be an invaluable reference for researchers
studying the human immune response, for clinicians and laboratory personnel involved in clinical and forensic HLA typing, and for human
geneticists, population biologists, and evolutionary biologists interested in HLA genes as markers of human diversity.
Audience
Researchers and research clinicians in immunology, immunohematology, genetics, cell and molecular biology, transplantation medicine, autoimmunity,
and biochemistry; researchers working in tissue typing laboratories, cancer biology, developmental biology, and researchers involved
in genome mapping and sequencing; rheumatologists, endocrinologists, and physicians working on HLA-associated diseases; pharmaceutical
industries working on HLA antibodies and kits.
Contents
Preface.
Abbreviations.
The Introductory Chapters:
Introduction.
Human Leukocyte Antigens (HLA) Determine Histocompatibility in
Transplantation.
The Organisation of HLA Genes Within the HLA Complex.
HLA Class I Antigens and Alleles: Workshops and Nomenclature.
HLA Class II Antigens and Alleles: Workshops and Nomenclature.
HLA Typing at the DNA Level.
HLA Class I and II Molecules Present Peptide
Antigens to Different Types of T Cell.
HLA Class I Molecules Control Natural Killer Cell Function.
Three-Dimensional Structures of HLA
Class I Molecules.
Three-Dimensional Structures of HLA Class II Molecules.
HLA Polymorphism, Peptide Binding Motifs and T-Cell Epitopes.
Evolution and Anthropology of HLA.
HLA and Disease.
Alloreactions in Transplantation.
The HLA Class I and Class II Loci.
| Bibliographic details |
Paperback, 416 pages, publication date: DEC-1999
ISBN-13: 978-0-12-545025-6
ISBN-10: 0-12-545025-7
Imprint: ACADEMIC PRESS
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| Price and Ordering |
Price:
EUR 65.95
GBP 43.99
USD 76.95
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Books and book related electronic products are priced in US dollars (USD), euro (EUR), and Great Britain Pounds (GBP). USD prices apply to the Americas and Asia Pacific. EUR prices apply in Europe and the Middle East. GBP prices apply to the UK and all other countries.
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Last update: 27 Sep 2008
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