Edited by
George Vande Woude, Director, Van Andel Research Institute, Grand Rapids, MI, USA
George Klein, Karolinska Insitutet, Stockholm, Sweden
Description
Volume 70 begins with two "Foundations in Cancer Research" articles, a staple of the
Advances in Cancer Research series.
The first article by Michael Stoker presents a review of some of the early advances made by cancer cell biology researchers. The second
article by Emmanuel Farber describes the methods by which researchers delineate the phenotype of cells and ways to alter these phenotypes
to prevent or delay carcinomas. Chidambaram and Dean illustrate the tumors and associated malformations of nevoid basal cell carcinoma.
Koli and Keski-Oja review the effects of how transforming growth factor-b regulates cell proliferation, differentiation, and morphogenesis
and its regulation by the steroid hormone superfamily. Jean-Marc Lemaitre and colleagues discuss the involvement of protooncogenes in
the control of the cell cycle and embryonic development with specific attention paid to c-Myc expression and c-Myc function. A review
of the various studies involving tumor-infiltrating lymphocytes and their possible role in cancer prevention is presented by Steven Rosenberg
and co-workers. Finally, Bruce Ponder and Darrin Smith review the genetic and biological aspects of multiple endocrine neoplasia type-2
syndromes and the phenotypes associated with
ret mutations.
Included in series
Advances in Cancer Research
Audience:
Researchers and students in basic and clinical science of cancer biology and oncology, plus related areas in genetics, immunology, virology, cell biology, and molecular biology.
