Edited by
M.P. Mattson, Laboratory of Neurosciences, National Institute on Aging, Gerontology Research Center, Baltimore, MD, USA
Description
The lipids of cellular membranes not only serve roles in controlling the structure and fluidity of the membrane, but are increasingly
recognized for their roles as signalling molecules and modifiers of membrane protein function. Recent studies described in this volume
reveal striking changes in membrane lipids during aging and in age-related diseases such as cancer, cardiovascular disease and neurodegenerative
disorders. Lipids including inositol phospholipids, cholesterol, sphingolipids and ceramides play important roles in signalling cellular
responses to stress and specific stimuli such as growth factors, cytokines and neurotransmitters. One or more of these lipid mediators
has been linked to the pathogenesis of age-related diseases.
This book provides a comprehensive review of specific membrane lipid
mediators and their roles in aging and age-related disease.
Included in series
Advances in Cell Aging and Gerontology
Audience:
Neuroscientists, biochemists, cell biologists, cardiologists, neurologists.
