This Month:

"Reversible severe combined immunodeficiency phenotype secondary to a mutation of the proton-coupled folate transporter", From Prof. Luigi Notarangelo’s group.

  Full article PDF freely accessible

Luigi D. Notarangelo, MD
Luigi D. Notarangelo, MD came to the Harvard Medical School in 2006 as a Professor of Pediatrics and Pathology. He is the Jeffrey Modell Chair of Pediatric Immunology Research at Children’s Hospital Boston. Dr. Notarangelo graduated in Medicine at the University of Pavia, Italy and completed his residency in Pediatrics and fellowships in Allergy and Immunology and in Human Genetics. He chaired the Department of Pediatrics at the University of Brescia, Italy from 2000 to 2006, and served as the President of the European Society of Immune Deficiencies from 2002 to 2006. He co-chairs the International Union of Immunological Societies Committee on Primary Immunodeficiencies. Dr. Notarangelo’s research interests focus on the molecular and cellular mechanisms of primary immunodeficiencies and on hematopoietic cell transplantation for these disease. Dr. Notarangelo has actively contributed to the characterization of the molecular bases of several immunodeficiencies, including SCID due to JAK3 deficiency, Omenn syndrome, CD40 deficiency, and isolated X-linked thrombocytopenia, a variant of the Wiskott-Aldrich syndrome.

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