Metabolizing Enzymes and Transporters Module
Metabolyzing Enzymes and Transporters Module
The Metabolizing Enzymes and Transporters Module is the world's largest database for drug-metabolizing enzymes and transporters and drug–drug interactions. It supports rapid and accurate assessments of drug candidates and their interactions with enzymes and other drugs.
- Access the world's best source of drug-metabolizing enzyme data
- Accurately predict drug–drug interactions
- Make key risk assessments on bioavailability, toxicity and more
- Predict adverse effects early and save research time and money
- Benefit from relevant search filters and categories
Metabolizing Enzymes and Transporters in focus
Dr. Kevin Lustig and Dr. Maria Thompson describe the impact of metabolizing enzyme
and transporter protein research on the cost and quality of clinical drug development.
Read more about the features and benefits of PharmaPendium's Metabolizing Enzymes
and Transporters Module in our special product profile.
Accurate prediction for all safety assessments
The Metabolizing Enzymes and Transporters Module helps you to more accurately predict DDIs under various conditions and with different subtypes and assemble improved DDI modeling sets to identify potential problems. Benefit from the powerful support for pre-clinical, clinical and post-market safety assessments.
The Metabolizing Enzymes and Transporters Story
Watch this exclusive video about drug–drug and drug–enzyme interactions and see how PharmaPendium's Metabolizing Enzymes and Transporters Module fits into your workflow.
Comparative data for confident drug
Assess possible drug–drug interactions based
on similarities with the targets, class,
common adverse effects, and structures of other drugs.
Make risk assessments on key topics, such as drug
interaction-induced toxicity and CYP interaction-induced
changes in bioavailability. The Metabolizing Enzymes
and Transporters Module supports all your key
Anticipate potential drug-drug interactions
Early discovery of critical drug–drug and drug–enzyme interactions that might lead to a lack of efficacy or a serious adverse event is easier with data from comprehensive regulatory sources and journals. This information can help users avoid late-stage drug failures due to unexpected changes in bioavailability, potentially saving millions of dollars in research and development costs. Make such predictions with confidence thanks to the Metabolizing Enzymes and Transporters Module.
Intelligent search functions
Search terms and filters that help you refine your search results and highlight what is most important to your research. Search key parameters and experimental conditions and apply filters to narrow down to the most relevant and actionable information. You also have the option to sort your results under multiple conditions. These include:
- Drug name
- Metabolites created
- Phase 2 Enzymes
- Dynamic pharmokinetics parameters
- Disease states
- Cint (Intrinsic Clearance)
- Cint (Intrinsic Clearance)
- Vmax (maximum rate of enzyme reaction)
- Transporters and effects on transporters
- Drug role (as substrate, inducer or inhibitor)
- Concomitant drugs