Pathway Studio

DiseaseFx

Linking effects of disease with molecular observation

Demo / Quote Login

 

diseasefx_main_image

 

Quantifiable Indication in Disease.
For reference and discovery.

DiseaseFx™ is a powerful informatics resource that helps you produce solid results from journals on molecular biology from Elsevier’s ScienceDirect as well as articles from other leading scientific publishers. Use DiseaseFx to support new discoveries, develop hypotheses, and create disease-specific mechanistic models. DiseaseFx supports in-house in silico biomarker discovery programs and pathway analysis of experimental data.

diseasefx_img1
The DiseaseFx knowledge base derives from peer-reviewed research findings that link human disease with molecular observations such as:
• Changes in the activity of proteins
• Changes in gene expression
• Changes in concentration of metabolites 
• Gene mutations and deletions
• Changes in epigenetic methylation observed in disease
• Explicit reference of genes, proteins, and metabolites as prognostic and diagnostic biomarkers.
diseasefx_bottom_line

From Research to Application.
DiseaseFx in your workflow.

Linking diseases with information from ClinicalTrials.gov, DiseaseFx enables you to smoothly transition from molecular observations to disease and clinical observations potential therapies. DiseaseFx integrates explicit references from clinical research regarding confirmed and potential prognostic and diagnostic biomarkers. It can provide a good first approach to determine the specificity of a particular protein as a disease biomarker. DiseaseFx provides decision support for prioritizing proteins that are involved in disease pathogenesis, or that are most specific for prognostic or diagnostic applications.

diseasefx
diseasefx_bottom_line

Adding DiseaseFx to Pathway Studio
DiseaseFx is available as an option, bundled with ChemEffect®, in Pathway Studio Web, or as an independent add-on component for Pathway Studio Enterprise. It is designed to be added to the Mammalian knowledge base. DiseaseFx for Pathway Studio Enterprise includes a disease-centric text-mining module for MedScan Reader and MedScan Enterprise that lets you extract information from literature, including your internal documents, to augment the knowledge base and to develop a focused data resource for use with Pathway Studio.

diseasefx_bottom_line

 

Read this DiseaseFX brochure to learn more.