Pharmaceutical Sciences

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725997Introducing the newest member of the pharmaceutical sciences family: Results in Pharma Sciences.

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JCR NEW topic collections now available


502690The Journal of Controlled Release has launched a new series of topic collections available to download. They provide an easy way for you to identify papers which are relevant to your own research. Dedicated to a specific topic, such as gene delivery, PEGylation, drug targeting; each compilation is complied from the top articles recently published in JCR

Latest open access research articles

Open access options
  • A microdialysis study of topically applied diclofenac to healthy humans: Passive versus iontophoretic delivery
    Publication year: 2011
    Source:Results in Pharma Sciences, Volume 1, Issue 1

    Birgit Falk Riecke, Else Marie Bartels, Søren Torp-Pedersen, Søren Ribel-Madsen, Henning Bliddal, Bente Danneskiold-Samsøe, Lars Arendt-Nielsen

    Topical application of NSAIDs is an alternative route to systemic administration when a local anti-inflammatory effect of the underlying tissue is a treatment option. The aim of the present microdialysis study was to assess and compare plasma and tissue levels of diclofenac when topically applied with or without iontophoresis in healthy adults. Fourteen healthy adults (26±9.4 years) were randomized to diclofenac applied by iontophoresis, or by a gel, in …

  • A simple protocol for preparation of a liposomal vesicle with encapsulated plasmid DNA that mediate high accumulation and reporter gene activity in tumor tissue
    Publication year: 2011
    Source:Results in Pharma Sciences, Volume 1, Issue 1

    Torben Gjetting, Thomas Lars Andresen, Camilla Laulund Christensen, Frederik Cramer, Thomas Tuxen Poulsen, Hans Skovgaard Poulsen

    The systemic delivery of gene therapeutics by non-viral methods has proven difficult. Transfection systems that are performing well in vitro have been reported to have disadvantageous properties such as rapid clearance and short circulation time often resulting in poor transfection efficiency when applied in vivo. Large unilaminary vesicles (LUV) with encapsulated nucleic acids designated stabilized-plasmid-lipo-particle (SPLP) have showed promising results in terms of systemic stability and accumulation in tumor tissue …

  • Advisory Board
    Publication year: 2011
    Source:Results in Pharma Sciences, Volume 1, Issue 1

  • Anti-angiogenic poly-L-lysine dendrimer binds heparin and neutralizes its activity
    Publication year: 2012
    Source:Results in Pharma Sciences, Volume 2

    Khuloud T. Al-Jamal, Wafa T. Al-Jamal, Kostas Kostarelos, John A. Turton, Alexander T. Florence

    The interaction between heparin, a polyanion, and a polycationic dendrimer with a glycine core and lysine branches Gly–Lys63(NH2)64 has been investigated. Complexation was assessed by transmission electron microscopy, size and zeta potential measurements, methylene blue spectroscopy, and measuring the anti-coagulant activity of heparin in vitro and in vivo. Complete association between the heparin and the dendrimer occurred a 1:1 mass ratio (2:1 molar ratio or +/−charge ratio) with formation of quasi-spherical complexes in the size …

  • Applying terahertz technology for nondestructive detection of crack initiation in a film-coated layer on a swelling tablet
    Publication year: 2012
    Source:Results in Pharma Sciences, Volume 2

    Wataru Momose, Hiroyuki Yoshino, Yoshifumi Katakawa, Kazunari Yamashita, Keiji Imai, Kazuhiro Sako, Eiji Kato, Akiyoshi Irisawa, Etsuo Yonemochi, Katsuhide Terada

    Here, we describe a nondestructive approach using terahertz wave to detect crack initiation in a film-coated layer on a drug tablet. During scale-up and scale-down of the film coating process, differences in film density and gaps between the film-coated layer and the uncoated tablet were generated due to differences in film coating process parameters, such as the tablet-filling rate in the coating machine, spray …

Conferences

May 15-19, 2011
"Liposomes in Jerusalem 2011"
 
Jerusalem, Israel

June 13-17, 2011
Pharmaceutical Sciences for the Future of Medicines
 
Prague, Czech Republic

July 30-August 3, 2011
The 38th Annual Meeting & Exposition of the Controlled Release Society
 
Gaylord National Resort and Convention Center, National Harbor, Maryland, USA

September 18-20, 2011
XX HELSINKI DRUG RESEARCH CONGRESS
 
Helsinki, Finland

October 23-27, 2011
2011 AAPS Annual Meeting and Exposition
 
Washington Convention Center
Washington, DC

June 26-29 2012 
10th International Symposium on Pharmaceutical Sciences 
Ankara, Turkey