Types of paper
Significant original research papers and pertinent reviews on all aspects of steroids will be considered for publication. Specifically, both experimental and theoretical studies dealing with the following areas of investigation are welcome: chemistry and physiochemistry; biosynthesis; metabolism; molecular biology; physiology; pharmacology; analytical techniques; comparative endocrinology; clinical research; mode of action (including that of related peptides); and the role of steroids on growth and differentiation. Relevant compounds also include non-steroidal analogs that are inhibitors or activators of steroid biosynthetic enzymes or ligands for steroid hormone receptors
Letters to the editor are welcome, for editing and publication at the discretion of the editor. Rapid Communications will be considered if material is of unusual interest and particularly timely.
Publication of Articles Describing the Isolation and Identification of New Steroids or the Synthesis of New Steroids or Steroid Derivatives
For information on Ethics in Publishing and Ethical guidelines for journal publication see http://www.elsevier.com/publishingethics and http://www.elsevier.com/ethicalguidelines.
When experimental animals are used, the materials and methods section must clearly indicate that adequate measures were taken to minimize pain or discomfort, and that the experiments were conducted in accordance with international standards on animal welfare as well as being compliant with local and national regulations. Studies are expected to be compliant with minimal standards as defined by the European Communities Council Directive of 24 November 1986 (86/609/EEC) http://europa.eu.int/comm/food/fs/aw/aw_legislation/scientific/86-609-eec_en.PDF and the National Institutes of Health Guide for the Care and Use of Laboratory Animals http://www.nap.edu/readingroom/books/labrats/ Full details of any anesthetic or analgesic dose and treatment must be given.Conflict of interest
All authors are requested to disclose any actual or potential conflict of interest including any financial, personal or other relationships with other people or organizations within three years of beginning the submitted work that could inappropriately influence, or be perceived to influence, their work. See also http://www.elsevier.com/conflictsofinterest. Further information and an example of a Conflict of Interest form can be found at: http://service.elsevier.com/app/answers/detail/a_id/286/supporthub/publishing.
Submission declaration and verification
Submission of an article implies that the work described has not been published previously (except in the form of an abstract or as part of a published lecture or academic thesis or as an electronic preprint, see http://www.elsevier.com/sharingpolicy), that it is not under consideration for publication elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere in the same form, in English or in any other language, including electronically without the written consent of the copyright-holder. To verify originality, your article may be checked by the originality detection service CrossCheck http://www.elsevier.com/editors/plagdetect.
All authors should have made substantial contributions to all of the following: (1) the conception and design of the study, or acquisition of data, or analysis and interpretation of data, (2) drafting the article or revising it critically for important intellectual content, (3) final approval of the version to be submitted.
Changes to authorship
Authors are expected to consider carefully the list and order of authors before submitting their manuscript and provide the definitive list of authors at the time of the original submission. Any addition, deletion or rearrangement of author names in the authorship list should be made only before the manuscript has been accepted and only if approved by the journal Editor. To request such a change, the Editor must receive the following from the corresponding author: (a) the reason for the change in author list and (b) written confirmation (e-mail, letter) from all authors that they agree with the addition, removal or rearrangement. In the case of addition or removal of authors, this includes confirmation from the author being added or removed.
Only in exceptional circumstances will the Editor consider the addition, deletion or rearrangement of authors after the manuscript been accepted. While the Editor considers the request, publication of the manuscript will be suspended. If the manuscript has already been published in an online issue, any requests approved by the Editor will result in a corrigendum.
This journal is part of our Article Transfer Service. This means that if the Editor feels your article is more suitable in one of our other participating journals, then you may be asked to consider transferring the article to one of those. If you agree, your article will be transferred automatically on your behalf with no need to reformat. Please note that your article will be reviewed again by the new journal. More information about this can be found here: http://www.elsevier.com/authors/article-transfer-service.
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As an author you (or your employer or institution) have certain rights to reuse your work. For more information see http://www.elsevier.com/copyright.
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The service will help authors comply with the National Institutes of Health (NIH) revised ''Public Access Policy,'' effective April 7, 2008. The NIH's revised policy requires that NIH-funded authors submit to PubMed Central (PMC), or have submitted on their behalf, their peer-reviewed author manuscripts, to appear on PMC no later than 12 months after final publication.Elsevier will send to PMC the final peer-reviewed manuscript, which was accepted for publication and sent to Elsevier's production department, and that reflects any author-agreed changes made in response to peer-review comments. Elsevier will authorize the author manuscript's public access posting 12 months after final publication. Following the deposit by Elsevier, authors will receive further communications from Elsevier and NIH with respect to the submission.
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Green open access
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This journal has an embargo period of 12 months.
Please write your text in good English (American or British usage is accepted, but not a mixture of these). Authors who feel their English language manuscript may require editing to eliminate possible grammatical or spelling errors and to conform to correct scientific English may wish to use the English Language Editing service available from Elsevier's WebShop (http://webshop.elsevier.com/languageediting/) or visit our customer support site (http://support.elsevier.com) for more information.
Submission to this journal proceeds totally online. Visit the submission site of the journal at http://ees.elsevier.com/steroids You will be guided through the creation and uploading of your files. The system automatically converts source files to a single PDF file of the article, which is used in the peer-review process. Please note that even though manuscript source files are converted to PDF files at submission for the review process, these source files are needed for further processing after acceptance. All correspondence, including notification of the Editor's decision and requests for revision, takes place by e-mail.
Please submit, with the manuscript, the names, addresses and e-mail addresses of 4 potential referees. Note that the editor retains the sole right to decide whether or not the suggested reviewers are used. Use of word processing software
It is important that the file be saved in the native format of the word processor used. The text should be in single-column format. Keep the layout of the text as simple as possible. Most formatting codes will be removed and replaced on processing the article. In particular, do not use the word processor's options to justify text or to hyphenate words. However, do use bold face, italics, subscripts, superscripts etc. When preparing tables, if you are using a table grid, use only one grid for each individual table and not a grid for each row. If no grid is used, use tabs, not spaces, to align columns. The electronic text should be prepared in a way very similar to that of conventional manuscripts (see also the Guide to Publishing with Elsevier: http://www.elsevier.com/guidepublication). Note that source files of figures, tables and text graphics will be required whether or not you embed your figures in the text. See also the section on Electronic artwork.
To avoid unnecessary errors you are strongly advised to use the 'spell-check' and 'grammar-check' functions of your word processor.
Manuscripts Arrange the manuscript in the following order: title page, abstract, keywords, text, acknowledgments, references, footnotes, tables, figure legends, and figures. Number the pages in sequence, with the title page as page 1, the abstract as page 2, etc. Text: Arrange the body of the manuscript in the following order:
Introduction, Experimental, Results, Discussion.
Provide the name and address of the corresponding author to whom questions and reprint requests should be sent. Give the name and address of the institution from which the work originated.
Arrange the text in the following order:
- Introduction: The rationale for the study. Provide a brief account of the nature, approach and importance of the study to be presented.
- Experimental: A clear and precise description of the experimental procedures. Identify all drugs and chemicals used, dosages, and routes of administration. All methods must be referenced and/or described in sufficient detail to enable a reader to repeat the experiment. For animal and human studies, the experimental protocol must be humane and ethical. In all manuscripts reporting the results of human studies, a statement must appear in the Experimental section indicating that approval was obtained from the institutional review board and that all human subjects signed written informed consent.
- Results: A factual account of the study's findings. Present these as logically appropriate in text, tables, or figures; do not repeat in the text what is demonstrated in a table or figure.
- Discussion: Place the results of the study in present and historical context and denote its importance to the field. Ensure that all conclusions are justified by the results of the study.
If there is more than one appendix, they should be identified as A, B, etc. Formulae and equations in appendices should be given separate numbering: Eq. (A.1), Eq. (A.2), etc.; in a subsequent appendix, Eq. (B.1) and so on. Similarly for tables and figures: Table A.1; Fig. A.1, etc.
• Title. Concise and informative. Titles are often used in information-retrieval systems. Avoid abbreviations and formulae where possible.
• Author names and affiliations. Please clearly indicate the given name(s) and family name(s) of each author and check that all names are accurately spelled. Present the authors' affiliation addresses (where the actual work was done) below the names. Indicate all affiliations with a lower-case superscript letter immediately after the author's name and in front of the appropriate address. Provide the full postal address of each affiliation, including the country name and, if available, the e-mail address of each author.
• Corresponding author. Clearly indicate who will handle correspondence at all stages of refereeing and publication, also post-publication. Ensure that the e-mail address is given and that contact details are kept up to date by the corresponding author.
• Present/permanent address. If an author has moved since the work described in the article was done, or was visiting at the time, a 'Present address' (or 'Permanent address') may be indicated as a footnote to that author's name. The address at which the author actually did the work must be retained as the main, affiliation address. Superscript Arabic numerals are used for such footnotes.
A concise and factual abstract is required (maximum length 250 words). The abstract should state briefly the purpose of the research, the principal results, and major conclusions. An abstract is often presented separately from the article, so it must be able to stand alone. References should be avoided but, if essential, they must be cited in full. Avoid non-standard or uncommon abbreviations; if they must be used, define them at their first mention in the abstract itself.
Although a graphical abstract is optional, its use is encouraged as it draws more attention to the online article. The graphical abstract should summarize the contents of the article in a concise, pictorial form designed to capture the attention of a wide readership. Graphical abstracts should be submitted as a separate file in the online submission system. Image size: Please provide an image with a minimum of 531 × 1328 pixels (h × w) or proportionally more. The image should be readable at a size of 5 × 13 cm using a regular screen resolution of 96 dpi. Preferred file types: TIFF, EPS, PDF or MS Office files. See http://www.elsevier.com/graphicalabstracts for examples.
Authors can make use of Elsevier's Illustration and Enhancement service to ensure the best presentation of their images and in accordance with all technical requirements: Illustration Service.
Highlights are mandatory for this journal. They consist of a short collection of bullet points that convey the core findings of the article and should be submitted in a separate editable file in the online submission system. Please use 'Highlights' in the file name and include 3 to 5 bullet points (maximum 85 characters, including spaces, per bullet point). See http://www.elsevier.com/highlights for examples.
Immediately after the abstract, provide a maximum of six keywords, avoiding general and plural terms and multiple concepts (avoid, for example, "and", "of"). Be sparing with abbreviations; only firmly established ones should be used.
Define abbreviations that are not standard in this field in a footnote to be placed on the first page of the article. Such abbreviations that are unavoidable in the abstract must be defined at their first mention there, as well as in the footnote. Ensure consistency of abbreviations throughout the article.
Acknowledge grants, sponsors, funding sources, and individuals who provided significant assistance. Include the affiliations of individuals being thanked. It is the author's responsibility to obtain permission from all those mentioned by name, because readers may infer their endorsement.
Units of measure
Standard metric units are preferred. SI units are optional, except that the use of Bq (becquerel) is not acceptable; use Ci (curie) or dpm (disintegrations per minute). Centrifugation should be described in terms of force (_g), not as rpm.
Refer to drugs by their approved generic names. If trade names are used, the generic equivalent should be given parenthetically at the first use. Identify compounds by their formal chemical name at first use; thereafter the trivial name may be used. All names should be in accordance with the most recent IUPAC-IUB rules on the nomenclature of steroids published in Pure and Applied Chemistry 61, 1783-1822, 1989. Substituted steroids should be named so that only one functional group is designated as a suffix and all other substituents are listed as X steroids 71 (2006) IX-XI prefixes. If the first letter of the suffix is a vowel, the terminal 'e' of the name of the hydrocarbon should be dropped (e.g., etiocholan-17-one). Unsaturation should be indicated by writing the locant number for the double bond(s) before the suffix (e.g., 3-hydroxyandrost-5-en-17-one). Trivial names may be modified by prefixes indicating substituents (e.g., 17-hydroxyprogesterone) but must not be more cumbersome than the systematic names they replace. Chemically impossible trivial names (e.g., 20-hydroxyprogesterone) are not acceptable. Alcohols are named as ols or hydroxy derivatives, not as dihydroketones. Isotope location should be designated by a prefix bracket placed directly before the part of the name to which it applies (i.e., without a space or hyphen): e.g., 3,20-dihydroxy-[4-14C]pregnan-7-one; [3-3H]methoxyandrostan-17-one, 11?,21-dihydroxy-[1,2-3H; 4-14C]pregnane-3,20-dione. Iodinated compounds, in which iodine is part of the structure, are to be labeled in the same manner; e.g., [16?-125I]iodoestradiol; 3-hydroxy-[21-125I]iodopregn-5-en-20-one.
Follow internationally accepted rules and conventions: use the international system of units (SI). If other quantities are mentioned, give their equivalent in SI. You are urged to consult IUPAC: Nomenclature of Organic Chemistry:http://www.iupac.org/publications/pac/1989/pdf/6110x1783.pdf for further information.
Identification of structure: Sufficient spectroscopic information must be presented to establish the structural identity of all new compounds, whether isolated as naturally occurring steroids or newly synthesized ones. These data should appear in the Experimental Section and be adequate for unambiguous structure elucidation. A list of proton or 1H and 13C NMR peaks is generally sufficient, but if structural identification was based on NMR data, peak assignments should also be given. Chemical shift data should be given only to two decimal places. Infrared absorptions, diagnostic for key functional groups, are also helpful, and high resolution mass spectroscopic data can provide an additional criterion of compound identity. When a series of closely related compounds is reported, spectroscopic data can be presented in a table, or full spectroscopic data for a representative member can be presented, with comments made on the spectral features unique to other members of the series. For known compounds, the source or literature reference(s) to the previous isolation or to the previous method of preparation and characterization must be provided.For known compounds, indicate the observed and literature melting points for crystalline solids, and/or the observed and literature optical rotations, in the following formats: mp xx oC (lit [ref] xx oC) and/or [α]DºC ± xxo (c, xx g/100 mL; solvent) (lit [ref] [α]D ºC ± xxo (c, xx g/100 mL; solvent). Provide comments (either in general or for individual compounds) comparing the observed 1H and 13C NMR data of known compounds with the literature values, e.g., “The 1H and 13C NMR data (xx MHz, solvent) agreed well with the literature values [ref].” It is not necessary to report complete data sets for known compounds. However, significantly different or improved data (e.g., different chemical shifts, data in different solvents, data taken at higher field, improved coupling analyses, etc.) should be reported in the Experimental Section or in a Table of NMR data and assignments.
Many naturally occurring steroids are isolated as glycoside derivatives. In such cases, the structures and absolute configuration of the individual sugar residues should be determined after hydrolysis. The absolute configuration of an individual sugar can be determined by comparing its optical rotation with the literature value for sugars of well-established absolute configuration. Another approach is direct comparison with authentic samples of the D and L sugars, or their derivatives, by high-pressure liquid chromatography (HPLC) or by gas chromatography (GC) on columns containing suitable chiral adsorbents, provided it is demonstrated that the enantiomeric compounds give separate peaks on the chiral columns.
Criteria for the purity of all compounds and of compounds with biological data: All new compounds need to be pure. Evidence of high purity is essential where biochemical or biological assay data are presented and related to compound structures; these compounds are termed "SAR compounds." The purity of SAR compounds should be more than 98 percent; the purity of other compounds should be more than 95 percent. Any questions regarding the purity of SAR compounds should appear in the Results.
The methods used to establish the purity of steroids subjected to biochemical or biological assays must be described in the Experimental Section. Most steroids obtained in pure form will be crystalline. Thus, there should be an attempt to purify and crystallize all products of chemical reactions or compounds isolated from plant extracts. Melting points should be recorded and reported for all crystalline compounds. It is strongly recommended that optical rotations be reported for new compounds. The weights and % yields should be reported for products isolated from chemical transformations.
Footnotes should be used sparingly. Number them consecutively throughout the article. Many word processors can build footnotes into the text, and this feature may be used. Otherwise, please indicate the position of footnotes in the text and list the footnotes themselves separately at the end of the article. Do not include footnotes in the Reference list.
• Make sure you use uniform lettering and sizing of your original artwork.
• Embed the used fonts if the application provides that option.
• Aim to use the following fonts in your illustrations: Arial, Courier, Times New Roman, Symbol, or use fonts that look similar.
• Number the illustrations according to their sequence in the text.
• Use a logical naming convention for your artwork files.
• Provide captions to illustrations separately.
• Size the illustrations close to the desired dimensions of the published version.
• Submit each illustration as a separate file.
A detailed guide on electronic artwork is available on our website:
You are urged to visit this site; some excerpts from the detailed information are given here.
If your electronic artwork is created in a Microsoft Office application (Word, PowerPoint, Excel) then please supply 'as is' in the native document format.
Regardless of the application used other than Microsoft Office, when your electronic artwork is finalized, please 'Save as' or convert the images to one of the following formats (note the resolution requirements for line drawings, halftones, and line/halftone combinations given below):
EPS (or PDF): Vector drawings, embed all used fonts.
TIFF (or JPEG): Color or grayscale photographs (halftones), keep to a minimum of 300 dpi.
TIFF (or JPEG): Bitmapped (pure black & white pixels) line drawings, keep to a minimum of 1000 dpi.
TIFF (or JPEG): Combinations bitmapped line/half-tone (color or grayscale), keep to a minimum of 500 dpi.
Please do not:
• Supply files that are optimized for screen use (e.g., GIF, BMP, PICT, WPG); these typically have a low number of pixels and limited set of colors;
• Supply files that are too low in resolution;
• Submit graphics that are disproportionately large for the content.
Please make sure that artwork files are in an acceptable format (TIFF, EPS, or MS Office files) and with good resolution, please see http://www.elsevier.com/artworkinstructions.
If together with your accepted article, you submit usable colour figures, then Elsevier will ensure, at no additional charge, that these figures will appear in colour on the Web (e.g., ScienceDirect and other sites) regardless of whether these illustrations are reproduced in colour in the printed version. For colour reproduction in print, you will receive information regarding the costs from Elsevier after receipt of your accepted article. For further information on the preparation of electronic artwork, please see http://www.elsevier.com/artworkinstructions [Please note: Because of technical complications that can arise in converting colour figures to "grey scale" (for the printed version should you not opt for colour in print), please submit in addition usable black-and-white files corresponding to all the colour illustrations].
Provide a concise legend for each figure that is sufficiently clear so that the figure can be understood without reference to the text. Legends to figures should be presented on a separate page. Identify and explain all abbreviations, symbols, and figure parts. The use of symbols in legends is restricted to standard ones that can be typeset; it is usually preferable to place the key symbols directly on the art. References
Citation in text
Please ensure that every reference cited in the text is also present in the reference list (and vice versa). Any references cited in the abstract must be given in full in the abstract itself. Unpublished results and personal communications are not recommended in the reference list, but may be mentioned in the text. If these references are included in the reference list they should follow the standard reference style of the journal and should include a substitution of the publication date with either "Unpublished results" or "Personal communication" Citation of a reference as "in press" implies that the item has been accepted for publication.
Increased discoverability of research and high quality peer review are ensured by online links to the sources cited. In order to allow us to create links to abstracting and indexing services, such as Scopus, CrossRef and PubMed, please ensure that data provided in the references are correct. Please note that incorrect surnames, journal/book titles, publication year and pagination may prevent link creation. When copying references, please be careful as they may already contain errors. Use of the DOI is encouraged.
As a minimum, the full URL should be given and the date when the reference was last accessed. Any further information, if known (DOI, author names, dates, reference to a source publication, etc.), should also be given. Web references can be listed separately (e.g., after the reference list) under a different heading if desired, or can be included in the reference list.
Please ensure that the words 'this issue' are added to any references in the list (and any citations in the text) to other articles in the same Special Issue.
Reference management software
Most Elsevier journals have a standard template available in key reference management packages. This covers packages using the Citation Style Language, such as Mendeley (http://www.mendeley.com/features/reference-manager) and also others like EndNote (http://www.endnote.com/support/enstyles.asp) and Reference Manager (http://refman.com/downloads/styles). Using plug-ins to word processing packages which are available from the above sites, authors only need to select the appropriate journal template when preparing their article and the list of references and citations to these will be formatted according to the journal style as described in this Guide. The process of including templates in these packages is constantly ongoing. If the journal you are looking for does not have a template available yet, please see the list of sample references and citations provided in this Guide to help you format these according to the journal style.
If you manage your research with Mendeley Desktop, you can easily install the reference style for this journal by clicking the link below:
When preparing your manuscript, you will then be able to select this style using the Mendeley plug-ins for Microsoft Word or LibreOffice. For more information about the Citation Style Language, visit http://citationstyles.org.
There are no strict requirements on reference formatting at submission. References can be in any style or format as long as the style is consistent. Where applicable, author(s) name(s), journal title/book title, chapter title/article title, year of publication, volume number/book chapter and the pagination must be present. Use of DOI is highly encouraged. The reference style used by the journal will be applied to the accepted article by Elsevier at the proof stage. Note that missing data will be highlighted at proof stage for the author to correct. If you do wish to format the references yourself they should be arranged according to the following examples:
Text: Indicate references by number(s) in square brackets in line with the text. The actual authors can be referred to, but the reference number(s) must always be given.
List: Number the references (numbers in square brackets) in the list in the order in which they appear in the text.
Reference to a journal publication:
 Van der Geer J, Hanraads JAJ, Lupton RA. The art of writing a scientific article. J Sci Commun 2010;163:51–9.
Reference to a book:
 Strunk Jr W, White EB. The elements of style. 4th ed. New York: Longman; 2000.
Reference to a chapter in an edited book:
 Mettam GR, Adams LB. How to prepare an electronic version of your article. In: Jones BS, Smith RZ, editors. Introduction to the electronic age, New York: E-Publishing Inc; 2009, p. 281–304.
Note shortened form for last page number. e.g., 51–9, and that for more than 6 authors the first 6 should be listed followed by 'et al.' For further details you are referred to 'Uniform Requirements for Manuscripts submitted to Biomedical Journals' (J Am Med Assoc 1997;277:927–34) (see also http://www.nlm.nih.gov/bsd/uniform_requirements.html).
Journal names should be abbreviated according to the List of Title Word Abbreviations: http://www.issn.org/services/online-services/access-to-the-ltwa/.
Elsevier accepts video material and animation sequences to support and enhance your scientific research. Authors who have video or animation files that they wish to submit with their article are strongly encouraged to include these within the body of the article. This can be done in the same way as a figure or table by referring to the video or animation content and noting in the body text where it should be placed. All submitted files should be properly labeled so that they directly relate to the video file's content. To ensure that your video or animation material is directly usable, please provide the files in one of our recommended file formats with a maximum size of 30 MB and running time of 5 minutes. Video and animation files will be published online in the electronic version of your article in Elsevier Web products, including ScienceDirect: http://www.sciencedirect.com. Please supply 'stills' with your files: you can choose any frame from the video or animation or make a separate image. These will be used instead of standard icons and will personalize the link to your video data. For more detailed instructions please visit our video instruction pages at http://www.elsevier.com/artworkinstructions. Note: since video and animation cannot be embedded in the print version of the journal, please provide text for both the electronic and the print version for the portions of the article that refer to this content.
The journal encourages authors to create an AudioSlides presentation with their published article. AudioSlides are brief, webinar-style presentations that are shown next to the online article on ScienceDirect. This gives authors the opportunity to summarize their research in their own words and to help readers understand what the paper is about. More information and examples are available at http://www.elsevier.com/audioslides. Authors of this journal will automatically receive an invitation e-mail to create an AudioSlides presentation after acceptance of their paper.
Preparation of supplementary data
Elsevier accepts supplementary material to support and enhance your scientific research. Supplementary files offer the author additional possibilities to publish supporting applications, movies, animation sequences, high-resolution images, background datasets, sound clips and more. Supplementary files supplied will be published online alongside the electronic version of your article in Elsevier Web products, including ScienceDirect: http://www.sciencedirect.com. To ensure that your submitted material is directly usable, please ensure that data is provided in one of our recommended file formats: TIFF, EPS or PDF. MS Office files (Word, Powerpoint, Excel). Authors should submit the material in electronic format together with the article and supply a concise and descriptive caption for each file. For more detailed instructions please visit our artwork instruction pages at http://www.elsevier.com/artworkinstructions."
Elsevier encourages authors to connect articles with external databases, giving readers access to relevant databases that help to build a better understanding of the described research. Please refer to relevant database identifiers using the following format in your article: Database: xxxx (e.g., TAIR: AT1G01020; CCDC: 734053; PDB: 1XFN). See http://www.elsevier.com/databaselinking for more information and a full list of supported databases.
The following list will be useful during the final checking of an article prior to sending it to the journal for review. Please consult this Guide for Authors for further details of any item.
Ensure that the following items are present:
One author has been designated as the corresponding author with contact details:
• E-mail address
• Full postal address
All necessary files have been uploaded, and contain:
• All figure captions
• All tables (including title, description, footnotes)
• Manuscript has been 'spell-checked' and 'grammar-checked'
• References are in the correct format for this journal
• All references mentioned in the Reference list are cited in the text, and vice versa
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DNA sequences and GenBank Accession numbers
Example 1: ''(GenBank accession nos. AI631510, AI631511,AI632198, and BF223228), a B-cell tumor from a chronic lymphatic leukemia (GenBank accession no. BE675048), and a T cell lymphoma (GenBank accession no. AA361117)''. Authors are encouraged to check accession numbers used very carefully. An error in a letter or number can result in a dead link. In the final version of the printed article, the accession number text will not appear bold or underlined (see Example 2 below).
Example 3: ''(GenBank accession nos. AI631510, AI631511, AI632198, and BF223228), a B-cell tumor from a chronic lymphatic leukemia (GenBank accession no. BE675048), and a T-cell lymphoma (GenBank accession no. AA361117)''.
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Letters to the Editor
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The Digital Object Identifier (DOI) may be used to cite and link to electronic documents. The DOI consists of a unique alpha-numeric character string which is assigned to a document by the publisher upon the initial electronic publication. The assigned DOI never changes. Therefore, it is an ideal medium for citing a document, particularly 'Articles in press' because they have not yet received their full bibliographic information. Example of a correctly given DOI (in URL format; here an article in the journal Physics Letters B):
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