Guide for Authors

  • All journal information and instructions compiled in one document (PDF) in just one mouse-click Author information pack

    • Aims and scope of the journal
    • Preliminary scope assessment
    • Page charges
    • Article types
    BEFORE YOU BEGIN
    • Ethics in publishing
    • Human and animal rights
    • Conflict of interest
    • Submission declaration and verification
    • Authorship
    • Changes to authorship
    • Copyright
    • Role of the funding source
    • Funding body agreements and policies
    • Open access
    • Language (usage and editing services)
    • Submission
    • Referees
    • General requirements
    PREPARATION
    • Use of word processing software
    • Article structure
    • Title page
    • Abstract
    • Graphical abstracts
    • Keywords
    • Abbreviations
    • Structure of text
    • Acknowledgements
    • Units
    • Math formulae
    • Footnotes
    • Artwork
    • Illustration services
    • Tables
    • References
    • Supplementary materials
    • Video data
    • AudioSlides
    • Supplementary data
    • Submission checklist
    • Editorial decisions and peer review
    AFTER ACCEPTANCE
    • Use of the Digital Object Identifier
    • Online proof correction
    • Offprints
    • Meeting information
    • Other resources for authors
    AUTHOR INQUIRIES

    Aims and scope of the journal

    The mission of Nanomedicine: Nanotechnology, Biology, and Medicine (Nanomedicine: NBM) is to promote the emerging interdisciplinary field of nanomedicine.
    The scope of the journal is publishing medical research related to nanoscience and nanotechnology in the life sciences, with a special emphasis on theoretical, basic, preclinical, and clinical studies addressing diagnosis, treatment, monitoring, prediction, and prevention of diseases.
    Manuscripts must fit the scope of the journal, i.e., it must be directly or closely related to medicine (diagnosis, treatment, monitoring, prognosis and prevention of diseases) and supporting biology, especially understanding biologic mechanisms related to nanoscience, nano-engineering and nano-technology research, i.e., research of man-made nanoscale objects, materials, and devices that improve medical outcome.
    Preferred topics include mechanistic insight into how nanoparticles influence cellular and sub-cellular mechanisms; improved imaging, diagnostics, and therapeutics; bioavailability, and toxicological assessment of nanomedicines; interactions of synthetic nanomaterials and nanodevices with cells, tissues, and living organisms; tissue- and receptor-specific (targeted) delivery, pharmacokinetics and pharmacodynamics of nanomedicines; regenerative medicine; translational models for nanomedicine research, case studies, and clinical trials in all subfields of human medicine. The journal website also presents important nanomedicine related information, such as future meetings, meeting summaries, Virtual Issues, news, societal subjects, public health, point of care monitoring, and ethical issues of nanomedicine.
    Application of nanoscale characterization techniques, such as STM, AFM, TEM, etc., is itself insufficient to qualify a work as ‘nanomedicine’. In vitro testing of materials and procedures in at least two cell lines is required, but in vivo is preferred with statistical evaluation. Case studies are welcome.

    Preliminary scope assessment

    To ensure that a submitted manuscript fits the scope of the journal, authors may solicit a preliminary scope assessment from the Editor-in-Chief by emailing a brief synopsis (title, topic, authors, and abstract) to both nnbm.editor@yahoo.com and nnbm.editor@gmail.com, and cc their message to nnbm.journaloffice@gmail.com. The purpose is to eliminate those submissions that are undoubtedly out of scope. Only scope is assessed at this stage. This evaluation is merely an advice and neither an invitation nor a rejection. A positive scope assessment does not guarantee acceptance in any way, as adherence to scope is only one of the fundamental requirements.

    Page charges

    Nanomedicine: NBM requires a $100 nonrefundable administrative fee for communications, original articles, scientific reviews, and case studies. Payment must be made through Submission Start. Exempt from this processing fee are Editorials, Perspectives, Letters, and manuscripts in which the corresponding author is an editorial board member or one of the Nanomedicine's top reviewers (those who have completed 5 or more reviews in the previous calendar year, or more than fifteen reviews over several years). In recent years, the number of manuscripts submitted each year has more than doubled, leading to a significant increase in the expenses related to the peer review process; the submission fee will help to offset a small portion of these expenses. Although this is the only fee required by the journal, this fee is nonrefundable.
    NOTE: Elsevier supports developing countries through its Research4Life program (more at: http://www.elsevier.com/about/corporate-responsibility/research-4-life?a=100832). The HINARI list (http://www.who.int/hinari/eligibility/en/) contains the names of eligible countries

    Article types

    Selection of the appropriate article type is very important because requirements do differ.

    COMMUNICATIONS: Communications are to disseminate new observations quickly to the scientific community. Length of communications should not exceed 1,500 words (including body text, and figure legends), and the article should have no more than 5 figures. No more than 25 references should be cited. Include an Abstract of 150 words or less without internal subheadings and citations. Upon acceptance, Communications enjoy priority in publishing and are entered into the next available issue.

    ORIGINAL ARTICLES: Full-length articles describe a full account about hypothesis-based research or theory in nanomedicine. Length should not exceed 5,000 words (including body text and figure legends), and the article should have no more than 8 figures in the main article. No more than 60 references should be cited. Include an Abstract of 150 words or less without internal subheadings and citations. The body text should include the four separate headings: Background, Methods, Results, and Discussion. Use of supplementary materials is recommended for detailed descriptions (see below).

    REVIEWS: Critical reviews of selected important topics in nanomedicine research are solicited from opinion leaders. Length of Reviews should not exceed 12,000 words (including body text, and figure legends), and the article should have no more than 15 figures. No more than 200 references should be cited in the review; additional references should be moved to the supplementary file(s). Include an Abstract of 150 words or less without internal subheadings and citations. Authors wishing to submit an unsolicited Review manuscript should send the title of the planned subject and a tentative Table of contents for the specific topics to be covered along with names of authors and a brief, 250-word synopsis to both nnbm.editor@yahoo.com and nnbm.editor@gmail.com and cc the message to nnbm.journaloffice@gmail.com for pre-submission approval by the Editor-in-Chief. .

    PERSPECTIVES IN NANOMEDICINE: Invited articles or brief editorial comments that represent opinions of recognized leaders in nanomedicine research and are written for the general scientific readership. Length should not exceed 3,500 words (including body text and figure legends).
    Authors wishing to submit an unsolicited Perspective manuscript should send the topic and title of the planned content along with names of authors and a brief, 250-word synopsis to nnbm.editor@yahoo.com and nnbm.editor@gmail.com and cc the message to nnbm.journaloffice@gmail.com for pre-submission approval by the Editor-in-Chief.

    LETTERS TO THE EDITOR: Letters to the Editor serves the purpose to comment on research published in Nanomedicine: NBM, including criticism or important comments. Letters may not exceed 500 words with maximum 10 references, one illustration, and one table. Letters and Responses to Letters are published together.

    TECHNICAL AND COMMERCIALIZATION NOTES: Information regarding new technologies, crucial business and regulatory issues, commercialization of new products in the field, including intellectual property and patenting, nanotechnology law, etc. Length of technical notes should not exceed 2,000 words (including body text and figure legends), 5 figures, and 10 references. Include an Abstract of 150 words or less without internal subheadings and citations.

    CASE STUDIES: These articles are descriptive or explanatory reports on actual clinical events based on an in-depth investigation of a single patient or a small group of individuals, related to use of nanomaterials, nanostructures, or nanomedicines in real-life context. Length of case studies should not exceed 3,500 words (including body text, and figure legends) with a maximum of 6 figures and 25 references. Include an Abstract of 150 words or less without internal subheadings and citations. Accepted case studies enjoy priority in publishing.

    For all article types, authors should provide in the manuscript only information essential for the discussion of results and utilize the Supporting Materials file to provide all experimental details and other non-essential supporting information. There are no limitations for length, figures, and references in Supplementary Materials. Communications and Original Articles complete with Supporting Materials must contain sufficient information to reproduce the experiments and data by someone experienced in the art.

    Meeting Announcements, Meeting Proceedings, and Meeting Summaries may be published on the Journal website under a different heading and without typesetting.

    The Journal may provide templates for material that will not receive typesetting. For questions, please contact Vindra Dass at v.dass@elsevier.com.

    Ethics in publishing

    Nanomedicine: NBM considers research and publication misconduct to be a serious breach of ethics, and will take such actions as necessary to address such misconduct. Plagiarism is defined as unreferenced use of published or unauthorized use of unpublished ideas, and may occur at any stage of planning, researching, writing, or publication. Plagiarism takes many forms, from “passing off” another's paper as the author's own paper, to copying or paraphrasing substantial parts of another paper (without attribution), to claiming results from research conducted by others. Plagiarism in all its forms constitutes unethical publishing behavior and is unacceptable. Duplicate submission/publication occurs when two or more papers, without full cross-reference, share the same hypothesis, data, discussion points, or conclusions. All manuscripts submitted to Nanomedicine: NBM are checked by CROSSCHECK, a professional software (http://www.ithenticate.com) before editorial consideration. For information on Ethics in publishing and Ethical guidelines for journal publication see http://www.elsevier.com/publishingethics and http://www.elsevier.com/journal-authors/ethics. Authors may also refer to the Committee on Publication Ethics (COPE) and the International Committee of Medical Journal Editors for full information.

    Permissions
    If any material has been published previously (figure, tables, etc), please provide written permission from the copyright holder to use such material. Authors are responsible for obtaining permission and payment of any fees associated with reuse. For more information, see the Permissions FAQ for Authors. For assistance, please contact Elsevier's Permissions Helpdesk: +1-800-523-4069 x3808; +1-215-239-3805; permissionshelpdesk@elsevier.com.

    Human and animal rights

    If the work involves the use of animal or human subjects, the author should ensure that the work described has been carried out in accordance with The Code of Ethics of the World Medical Association (Declaration of Helsinki) for experiments involving humans http://www.wma.net/en/30publications/10policies/b3/index.html; EU Directive 2010/63/EU for animal experiments http://ec.europa.eu/environment/chemicals/lab_animals/legislation_en.htm; Uniform Requirements for manuscripts submitted to Biomedical journals http://www.icmje.org. Authors should include a statement in the manuscript that informed consent was obtained for experimentation with human subjects. The privacy rights of human subjects must always be observed.
    Authors should include a statement in the manuscript that informed consent was obtained for experimentation with human subjects. The privacy rights of human subjects must always be observed.
    For studies involving human or animal research, indicate approval by the institution's human or animal subject review committee in the Methods section of the manuscript. Include an additional statement of the humane care of the animals with animal studies and a statement of informed consent or exempt classification by the IRB with human studies.

    Conflict of interest

    Authors are required to acknowledge all funding sources that supported their work as well as all institutional or corporate affiliations of the authors. Each submission must also include a publishable statement on the title page disclosing any commercial associations, current and within the past five years that might pose a potential, perceived, or real conflict of interest. These include grants, patent licensing arrangements, consultancies, stock or other equity ownership, advisory board memberships, or payments for conducting or publicizing the study.
    When no competing interests are present, include a statement on the title page. Further information and an example of a Conflict of Interest form can be found at: http://help.elsevier.com/app/answers/detail/a_id/286/p/7923. See also http://www.elsevier.com/conflictsofinterest.
    When no competing interests are present, include a statement on the title page.

    Submission declaration and verification

    Submission of an article implies that the work described has not been published previously (except in the form of an abstract or as part of a published lecture or academic thesis or as an electronic preprint, see http://www.elsevier.com/postingpolicy), that it is not under consideration for publication elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere in the same form, in English or in any other language, including electronically without the written consent of the copyright-holder. To verify originality, your article may be checked by the originality detection service CrossCheck http://www.elsevier.com/editors/plagdetect.

    Authorship

    The corresponding author must certify that all listed authors meet the Authorship and Contributorship criteria of the International Committee of Medical Journal Editors detailed at http://www.icmje.org/ethical_1author.html, according to which each participant:
    1) made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data;
    2) drafted the article or revised it critically for important intellectual content; and
    3) gives approval of the submitted manuscript and subsequent versions.

    All authors of a submitted manuscript must sign a form declaring that they meet all of the above criteria for authorship, approve the most recent submitted version of the manuscript, and take full responsibility for the manuscript. This form will be provided to the corresponding author when the Editors reach a decision that the manuscript may be potentially publishable. Those who do not meet all the criteria for authorship may be listed in the Acknowledgments. Examples of contributors listed in acknowledgements include a person who provided purely technical help, writing assistance, assistance with study desgn, data collection, or a department chairperson who provided only general support.

    Changes to authorship

    This policy concerns the addition, deletion, or rearrangement of author names in the authorship of accepted manuscripts:
    Before the accepted manuscript is published in an online issue: Requests to add or remove an author, or to rearrange the author names, must be sent to the Journal Manager from the corresponding author of the accepted manuscript and must include: (a) the reason the name should be added or removed, or the author names rearranged and (b) written confirmation (e-mail, fax, letter) from all authors that they agree with the addition, removal or rearrangement. In the case of addition or removal of authors, this includes confirmation from the author being added or removed. Requests that are not sent by the corresponding author will be forwarded by the Journal Manager to the corresponding author, who must follow the procedure as described above. Note that: (1) Journal Managers will inform the Journal Editors of any such requests and (2) publication of the accepted manuscript in an online issue is suspended until authorship has been agreed.
    After the accepted manuscript is published in an online issue: Any requests to add, delete, or rearrange author names in an article published in an online issue will follow the same policies as noted above and result in a corrigendum.

    Copyright

    This journal offers authors a choice in publishing their research: Open access and Subscription.

    For subscription articles
    Upon acceptance of an article, authors will be asked to complete a 'Journal Publishing Agreement' (for more information on this and copyright, see http://www.elsevier.com/copyright). An e-mail will be sent to the corresponding author confirming receipt of the manuscript together with a 'Journal Publishing Agreement' form or a link to the online version of this agreement.
    Subscribers may reproduce tables of contents or prepare lists of articles including abstracts for internal circulation within their institutions. Permission of the Publisher is required for resale or distribution outside the institution and for all other derivative works, including compilations and translations (please consult http://www.elsevier.com/permissions). If excerpts from other copyrighted works are included, the author(s) must obtain written permission from the copyright owners and credit the source(s) in the article. Elsevier has preprinted forms for use by authors in these cases: please consult http://www.elsevier.com/permissions.

    For open access articles
    Upon acceptance of an article, authors will be asked to complete an 'Exclusive License Agreement' (for more information see http://www.elsevier.com/OAauthoragreement). Permitted reuse of open access articles is determined by the author's choice of user license (see http://www.elsevier.com/openaccesslicenses).

    Retained author rights
    As an author you (or your employer or institution) retain certain rights. For more information on author rights for:
    Subscription articles please see http://www.elsevier.com/journal-authors/author-rights-and-responsibilities.
    Open access articles please see http://www.elsevier.com/OAauthoragreement.

    Role of the funding source

    You are requested to identify who provided financial support for the conduct of the research and/or preparation of the article and to briefly describe the role of the sponsor(s), if any, in study design; in the collection, analysis and interpretation of data; in the writing of the report; and in the decision to submit the article for publication. If the funding source(s) had no such involvement then this should be stated.

    Funding body agreements and policies

    Elsevier has established agreements and developed policies to allow authors whose articles appear in journals published by Elsevier, to comply with potential manuscript archiving requirements as specified as conditions of their grant awards. To learn more about existing agreements and policies please visit http://www.elsevier.com/fundingbodies.

    Open access

    This journal offers authors a choice in publishing their research:

    Open access
    • Articles are freely available to both subscribers and the wider public with permitted reuse
    • An open access publication fee is payable by authors or their research funder
    Subscription
    • Articles are made available to subscribers as well as developing countries and patient groups through our access programs (http://www.elsevier.com/access)
    • No open access publication fee

    All articles published open access will be immediately and permanently free for everyone to read and download. Permitted reuse is defined by your choice of one of the following Creative Commons user licenses:
    Creative Commons Attribution-NonCommercial-ShareAlike (CC BY-NC-SA): for non-commercial purposes, lets others distribute and copy the article, to create extracts, abstracts and other revised versions, adaptations or derivative works of or from an article (such as a translation), to include in a collective work (such as an anthology), to text and data mine the article, as long as they credit the author(s), do not represent the author as endorsing their adaptation of the article, do not modify the article in such a way as to damage the author's honor or reputation, and license their new adaptations or creations under identical terms (CC BY-NC-SA).
    Creative Commons Attribution-NonCommercial-NoDerivs (CC BY-NC-ND): for non-commercial purposes, lets others distribute and copy the article, and to include in a collective work (such as an anthology), as long as they credit the author(s) and provided they do not alter or modify the article.

    Elsevier has established agreements with funding bodies, http://www.elsevier.com/fundingbodies. This ensures authors can comply with funding body open access requirements, including specific user licenses, such as CC BY. Some authors may also be reimbursed for associated publication fees. If you need to comply with your funding body policy, you can apply for the CC BY license after your manuscript is accepted for publication.

    To provide open access, this journal has a publication fee which needs to be met by the authors or their research funders for each article published open access.
    Your publication choice will have no effect on the peer review process or acceptance of submitted articles.

    The open access publication fee for this journal is $3,000, excluding taxes. Learn more about Elsevier's pricing policy: http://www.elsevier.com/openaccesspricing.

    Language (usage and editing services)

    Please write your text in good English (American or British usage is accepted, but not a mixture of these). Authors who feel their English language manuscript may require editing to eliminate possible grammatical or spelling errors and to conform to correct scientific English may wish to use the English Language Editing service available from Elsevier's WebShop (http://webshop.elsevier.com/languageediting/) or visit our customer support site (http://support.elsevier.com) for more information.

    Submission

    Our online submission system guides you stepwise through the process of entering your article details and uploading your files. The system converts your article files to a single PDF file used in the peer-review process. Editable files (e.g., Word, LaTeX) are required to typeset your article for final publication. All correspondence, including notification of the Editor's decision and requests for revision, is sent by e-mail.

    Submit your article
    Please submit your article via http://ees.elsevier.com/nano/.

    Referees

    Please submit the names and institutional e-mail addresses of several potential referees. For more details, visit our Support site. Note that the editor retains the sole right to decide whether or not the suggested reviewers are used.

    General requirements

    1) The manuscript must be of INTERDISCIPLINARY nature, representing the overlapping fields nanoscience and nanotechnology with biology, and medicine.
    2) NOVELTY and ORIGINALITY are of primary importance. The results presented must significantly advance the field and improve scientific knowledge. Manuscripts with similar approaches that have already been undertaken by other groups should be submitted to appropriate journals. Originality of submissions is routinely checked by the editors using professional software.
    3) SIGNIFICANCE: Accounts of research must appeal to a broad readership. In the cover letter, authors should provide a paragraph explaining how the work differs from the knowledge available in the literature and describe how it improves or has the potential to improve medicine.
    4) REPRODUCIBILITY: Methods and materials should be reproducible and - in general - results and conclusions must move the field forward. Experimental studies must include at least in vitro results (one of them in an appropriately selected healthy cell line), although in vivo is preferred. Accordingly, synthesis and characterization of nanotechnology-based medicines (i.e., substances that promote healing) must accompany bioavailability and toxicity data and their comprehensive evaluation.
    Manuscripts that do not satisfy these general requirements will not be sent out for peer review and will be returned to the authors.

    Use of word processing software

    It is important that the file be saved in the native format of the word processor used. The text should be in single-column format. Keep the layout of the text as simple as possible. Most formatting codes will be removed and replaced on processing the article. In particular, do not use the word processor's options to justify text or to hyphenate words. However, do use bold face, italics, subscripts, superscripts etc. When preparing tables, if you are using a table grid, use only one grid for each individual table and not a grid for each row. If no grid is used, use tabs, not spaces, to align columns. The electronic text should be prepared in a way very similar to that of conventional manuscripts (see also the Guide to Publishing with Elsevier: http://www.elsevier.com/guidepublication). Note that source files of figures, tables and text graphics will be required whether or not you embed your figures in the text. See also the section on Electronic artwork.
    To avoid unnecessary errors you are strongly advised to use the 'spell-check' and 'grammar-check' functions of your word processor.

    NEW: At first submission, manuscripts may be submitted as single Word or PDF files, including references, figure legends, figures, and tables. All manuscript components need to be included to allow for evaluation of your manuscript. Graphical Abstract files are required at initial submission. If the editors determine that the work is potentially publishable, source files of the manuscript, figures, and tables will be required as well as other submission elements such as permissions and the authorship agreement form (see below). Include a cover letter and title page with counts as specified below.

    Article structure

    Submission items include a cover letter, a list of suggested reviewers, text for the graphical abstract, image for the graphical abstract, the manuscript (including title page, abstract, manuscript text [divided into Background, Methods, Results, and Discussion for Original Articles], references, and figure legends), tables, and figures. Authors are advised to upload supporting information in Supplementary Material and permissions (see below) if needed. Revised manuscripts should also be accompanied by a unique file (separate from the cover letter) with responses to reviewers’ comments. The preferred order of files is as follows: cover letter, suggested reviewers, response to reviews (revised manuscripts only), graphical abstract files, manuscript file, table(s), figure(s), supplementary material, permission(s), if needed. Files should be labeled with appropriate and descriptive file names (e.g., SmithManuscript.doc, Figure1.eps, Table3.doc, Supplementary.pdf). If a revision is requested, upload text, tables, and figures as separate files. Do not embed figures or tables into the text document. Please upload your revised text as a Word file, and upload text-based Supplementary Materials as a PDF. All manuscripts must conform to Uniform Requirements for Manuscripts Submitted to Biomedical Journals. Cover letter Be sure to state that the manuscript, or any part of it, has not been published and will not be submitted elsewhere for publication while being considered by the journal Nanomedicine: NBM in the cover letter. If there is any overlap between the submission and any other material, published or submitted, detail the nature of and reason for the overlap; as relevant, upload a copy of the other material.

    Title page

    Essential title page information
    Title. Concise and informative. Titles are often used in information-retrieval systems. Avoid abbreviations and formulae where possible. A title should describe the article's content clearly and precisely and allow the reader to decide whether it would be appropriate to consult the article further. The title is the advertisement for the article; a poorly titled article may never reach its target audience, so be specific. Omit unnecessary words such as “Novel,” “New,” “A study of,” “Investigations of,” “Observations on,” etc. Do not use abbreviations and jargon. Avoid overinflated, bombastic “marketing” titles. Indexing and abstracting services depend on the accuracy of the title and keywords used in cross-referencing are extracted from the title itself.
    Author names and affiliations. Where the family name may be ambiguous (e.g., a double name), please indicate this clearly. Present the authors' affiliation addresses (where the actual work was done) below the names. Indicate all affiliations with a lower-case superscript letter immediately after the author's name and in front of the appropriate address. Provide the full postal address of each affiliation, including the country name and, if available, the e-mail address of each author.
    Corresponding author. Clearly indicate who will handle correspondence at all stages of refereeing and publication, also post-publication. Ensure that phone numbers (with country and area code) are provided in addition to the e-mail address and the complete postal address. Contact details must be kept up to date by the corresponding author.
    Present/permanent address. If an author has moved since the work described in the article was done, or was visiting at the time, a 'Present address' (or 'Permanent address') may be indicated as a footnote to that author's name. The address at which the author actually did the work must be retained as the main, affiliation address. Superscript Arabic numerals are used for such footnotes.
    The title page must include the word count for abstract; complete manuscript word count (including body text and figure legends, but excluding abstract, title page, and references), and number of figures/tables. There is no length limit on Supplementary Material. Manuscripts with over-the-limit word counts will be returned to the authors without further review. The title page must include statements of funding or conflicts of interest. Please make note of any prior presentation of abstracts at meetings regarding the research.

    Abstract

    A concise and factual summary of 150 words or less without internal subheadings and citations is required. The abstract should state briefly the purpose of the research, the principal results, and major conclusions. An abstract is often presented separately from the article, so it must be able to stand alone. For this reason, references and abbreviations should be avoided, but, if essential, they must be defined at their first mention in the abstract itself. Insert 3 to 5 key words after the abstract. Be sure to include the abstract in the manuscript file.

    Graphical abstracts

    Authors are required to submit a graphical abstract for their article containing one image and a short description; both should briefly summarize the essence of the paper in a concise form designed to capture the attention of a wide readership and for compilation of databases. Graphical abstracts should be submitted as a separate file in the online submission system.
    The image should present the key points of the paper in a concise, pictorial form designed to seize the attention of readers and should not contain more than four panels. Please submit one image (in .tif or .eps format); see below for further resolution requirements. The text component should be ~50-100 words in .doc format, and it should not be the same as the abstract in the manuscript. If a figure in the manuscript is used as the graphical abstract image, please note this at the end of the abstract (i.e.: Graphical Abstract: Figure 2), and refer to the system's instructions for uploading.
    Examples of successful graphical abstract images and a link to Graphical Abstract Polishing can be found at http://www.elsevier.com/wps/find/authorsview.authors/graphicalabstracts; see also a recent issue of the Journal, particularly Example 1, Example 2, Example 3.
    Authors can make use of Elsevier's Illustration and Enhancement service to ensure the best presentation of their images also in accordance with all technical requirements: Illustration Service.

    Keywords

    Immediately after the abstract, provide a maximum of 6 keywords, using American spelling and avoiding general and plural terms and multiple concepts (avoid, for example, 'and', 'of'). Be sparing with abbreviations: only abbreviations firmly established in the field may be eligible. These keywords will be used for indexing purposes.

    Abbreviations

    Define abbreviations that are not standard in this field in a footnote to be placed on the first page of the article. Such abbreviations that are unavoidable in the abstract must be defined at their first mention there, as well as in the footnote. Ensure consistency of abbreviations throughout the article.

    Structure of text

    For Communications and Original Articles, the text should include the headings Background, Methods, Results, and Discussion. Only essential data and descriptions should be provided in the Methods and Results. All experimental details including synthetic and analytical procedures must be provided as SUPPLEMENTARY MATERIALS (see details below). All pages must be numbered. Abbreviations must be parenthetically notated at first mention in the text. Each table and figure must be mentioned in the text. Reports of studies on humans and animals must indicate that each study has been approved by an institutional review committee and the procedures followed are in accordance with institutional guidelines. Provide generic rather than trademarked names of drugs.

    Acknowledgements

    The acknowledgments section recognizes substantive contributions of individuals who do not meet the criteria for authorship (see below). The Editorial Office must receive written, signed consent from each person recognized in the acknowledgments to be mentioned in the article because acknowledgment can imply endorsement of data and conclusions. (See a sample of an Acknowledgement.) Upload each permission separately in the online system. Do not include statements of funding, conflicts, or other disclosures in the Acknowledgments; these must appear on the title page.

    Units

    Follow internationally accepted rules and conventions: use the international system of units (SI). If other units are mentioned, please give their equivalent in SI.

    Math formulae

    Present simple formulae in the line of normal text where possible and use the solidus (/) instead of a horizontal line for small fractional terms, e.g., X/Y. In principle, variables are to be presented in italics. Powers of e are often more conveniently denoted by exp. Number consecutively any equations that have to be displayed separately from the text (if referred to explicitly in the text).

    Footnotes

    Do not use footnotes in the text.

    Artwork

    Electronic artwork
    Figures must be of professional quality and suitable for evaluation purposes. Be sure all font is at a readable size. When possible, please use first-generation artwork. If a revision is requested, source files must be provided: Figures must be submitted in electronic figure file format: .tif, .eps, or .jpg format. Figures may be black and white line art, graphs, halftones (photographs), or color. Line art (black lines on a white background) must have a minimum resolution of 1,000 ppi. Combination line art (e.g., line art with gray fill patterns) must be created at 500 ppi. Black and white or color photographs must have a minimum resolution of 300 ppi. Illustrations should be saved at the recommended resolution setting and sized as close to a column width (3 to 4 inches) as possible. Create figures in scale with each other to the extent possible. Avoid background gridlines and other formatting that do not convey information (e.g., superfluous use of 3-dimensional formatting, background shadings). Use uniform lettering and sizing of all original artwork. As a general rule the lettering on the artwork should have a finished, printed size of 7 points. Smaller lettering will yield barely legible text. Recommended font choices include Arial, Helvetica, or Symbol. Labeling of multipart figures (eg, A, B, C...) should use capital letters only and should be done consistently, preferably using uppercase type (Arial, Helvetica or Universe, 11 or 12 points) in the lower-right corner of the figure. Avoid headings on the figure when possible. Additional information on preparation of electronic artwork can be found in the Artwork Instructions available at http://www.elsevier.com/authors. For best results, please follow these guidelines carefully. There is no charge for publication of color illustrations. General points
    • Make sure you use uniform lettering and sizing of your original artwork.
    • Embed the used fonts if the application provides that option.
    • Aim to use the following fonts in your illustrations: Arial, Courier, Times New Roman, Symbol, or use fonts that look similar.
    • Number the illustrations according to their sequence in the text.
    • Use a logical naming convention for your artwork files.
    • Provide captions to illustrations separately.
    • Size the illustrations close to the desired dimensions of the printed version.
    • Submit each illustration as a separate file.
    A detailed guide on electronic artwork is available on our website: http://www.elsevier.com/artworkinstructions
    Please do not:
    • Supply files that are optimized for screen use (e.g., GIF, BMP, PICT, WPG); these typically have a low number of pixels and limited set of colors;
    • Supply files that are too low in resolution;
    • Submit graphics that are disproportionately large for the content.

    Illustration services

    Elsevier's WebShop (http://webshop.elsevier.com/illustrationservices) offers Illustration Services to authors preparing to submit a manuscript but concerned about the quality of the images accompanying their article. Elsevier's expert illustrators can produce scientific, technical and medical-style images, as well as a full range of charts, tables and graphs. Image 'polishing' is also available, where our illustrators take your image(s) and improve them to a professional standard. Please visit the website to find out more.

    Figure captions
    Ensure that each illustration has a caption. Supply captions separately, not attached to the figure. A caption should comprise a brief title (not on the figure itself) and a description of the illustration. Keep text in the illustrations themselves to a minimum but explain all symbols and abbreviations used.

    Tables

    Number tables consecutively in accordance with their appearance in the text. Table numbers should be Arabic, followed by a period and a brief title. Upload each table as a separate file. Use the same type size as in the text where possible. Supply a brief heading for each column. Do not use vertical lines between columns. Use horizontal lines above and below the column headings and at the bottom of the table only. Use extra space to delineate sections within the table. Abbreviations used in the table must be defined in a footnote to the table. Indicate footnotes in this order: *, †, ‡, §, ||, ¶, #, **, ††, ‡‡, §§, ||||, ¶¶, etc. Be sparing in the use of tables and ensure that the data presented in tables do not duplicate results described elsewhere in the article.

    References

    Citation in text
    Cite references in numeric order according to the first mention in the text. Accuracy of reference data is the responsibility of the author. Verify all references against original sources. “In press” citations must have been accepted for publication and the name of the journal or book publisher must be included; these citations must be updated before publication. Unpublished results and personal communications should not appear in the reference list but may be mentioned in the text. Authors wishing to cite unpublished material must have a letter of permission from the originator of the communication to do so. This letter should be submitted with the manuscript. Please ensure that every reference cited in the text is also present in the reference list (and vice versa).

    Reference links
    Increased discoverability of research and high quality peer review are ensured by online links to the sources cited. In order to allow us to create links to abstracting and indexing services, such as Scopus, CrossRef and PubMed, please ensure that data provided in the references are correct. Please note that incorrect surnames, journal/book titles, publication year and pagination may prevent link creation. When copying references, please be careful as they may already contain errors. Use of the DOI is encouraged.

    Web references
    As a minimum, the full URL should be given and the date when the reference was last accessed. Any further information, if known (DOI, author names, dates, reference to a source publication, etc.), should also be given. Web references can be listed separately (e.g., after the reference list) under a different heading if desired, or can be included in the reference list.

    References in a special issue
    Please ensure that the words 'this issue' are added to any references in the list (and any citations in the text) to other articles in the same Special Issue.

    Reference style
    References can be in any style or format as long as the style is consistent. Author(s) name(s), journal title/book title, article title, year of publication, volume and issue or book chapter and the pagination must be present. The reference style required by the journal will be applied to the published version by Elsevier.

    For those who wish to format the references, if using EndNote software, the journal reference style is Embellished Vancouver (Style 3a). Reference format should conform to the examples shown below, and journal abbreviations should conform to the style used in the Cumulated Index Medicus.

    The style of citation should be as follows:

    Journals: authors' last names and initials; title of article; journal name; date; volume number, and inclusive pages (list all authors when six or fewer; when seven or more, list six and add et al):
    1. Graeber GM, Gupta NC, Murray GF. Positron emission tomographic imaging with fluorodeoxyglucose is efficacious in evaluating malignant pulmonary disease. J Thorac Cardiovasc Surg 1999;117:719-27.
    2. Lytle BW, Blackstone EH, Loop FD, Houghtaling PL, Arnold JH, Akhrass R, et al. Two internal thoracic artery grafts are better than one. J Thorac Cardiovasc Surg 1999;117:855-72.

    Books: authors' last names and initials; chapter title, editor's name, book title, edition, city, publisher, date, and pages:
    1. Mollnes TE. Analysis of in vivo complement activation: In: Herzenberg LA, Weir DM, Herzenberg LA, Blackwell C, editors. Weir's handbook of experimental immunology. Volume 78, 5th ed. Boston: Blackwell Science; 1997, p. 1-8.

    Journal abbreviations source
    Journal names should be abbreviated according to the List of Title Word Abbreviations: http://www.issn.org/services/online-services/access-to-the-ltwa/.

    Supplementary materials

    Nanomedicine: NBM accepts supplementary data files to accompany the online article, allowing authors to support and enhance their papers. Supplementary materials may include experimental details, additional images, background datasets, video clips, etc. Experiments should be described in such detail that someone trained in the art could repeat the experiment or measurement. Please provide text-based data as a separate PDF file when submitting your manuscript. All supplementary materials are subject to peer review but will not be edited by Nanomedicine: NBM and will be posted as provided by the authors. There are no limitations for length, figures, and references in Supporting Materials.

    Video data

    Elsevier accepts video material and animation sequences to support and enhance your scientific research. Authors who have video or animation files that they wish to submit with their article are strongly encouraged to include links to these within the body of the article. This can be done in the same way as a figure or table by referring to the video or animation content and noting in the body text where it should be placed. All submitted files should be properly labeled so that they directly relate to the video file's content. In order to ensure that your video or animation material is directly usable, please provide the files in one of our recommended file formats with a preferred maximum size of 50 MB. Video and animation files supplied will be published online in the electronic version of your article in Elsevier Web products, including ScienceDirect: http://www.sciencedirect.com. Please supply 'stills' with your files: you can choose any frame from the video or animation or make a separate image. These will be used instead of standard icons and will personalize the link to your video data. For more detailed instructions please visit our video instruction pages at http://www.elsevier.com/artworkinstructions. Note: since video and animation cannot be embedded in the print version of the journal, please provide text for both the electronic and the print version for the portions of the article that refer to this content.

    AudioSlides

    The journal encourages authors to create an AudioSlides presentation with their published article. AudioSlides are brief, webinar-style presentations that are shown next to the online article on ScienceDirect. This gives authors the opportunity to summarize their research in their own words and to help readers understand what the paper is about. More information and examples are available at http://www.elsevier.com/audioslides. Authors of this journal will automatically receive an invitation e-mail to create an AudioSlides presentation after acceptance of their paper.

    Supplementary data

    Elsevier accepts electronic supplementary material to support and enhance your scientific research. Supplementary files offer the author additional possibilities to publish supporting applications, high-resolution images, background datasets, sound clips and more. Supplementary files supplied will be published online alongside the electronic version of your article in Elsevier Web products, including ScienceDirect: http://www.sciencedirect.com. In order to ensure that your submitted material is directly usable, please provide the data in one of our recommended file formats. Authors should submit the material in electronic format together with the article and supply a concise and descriptive caption for each file. For more detailed instructions please visit our artwork instruction pages at http://www.elsevier.com/artworkinstructions.

    Submission checklist

    The order of the documents should be as follows:
    • Cover letter stating that the manuscript or any part of it has not and will not be submitted or published elsewhere (initial submission)
    • Suggestions for potential reviewers (initial submission)
    • Point-by-point response to reviewers and editors (revised submissions)
    • Graphical Abstract (text in .doc format; image in .eps, .tif, or .jpg format depending on article type)
    Manuscript (in .doc format for revised submissions):
    • Title page
    • Title of article
    • Full names(s), academic degree(s), affiliation(s) and titles of author(s)
    • Author to whom correspondence, proof, and reprint requests are to be sent, including address and business and home telephone numbers, fax number, and e-mail address
    • Any conflict of interest statement(s), disclosure(s), and/or financial support information, including donations
    • Word count for the abstract, a complete manuscript word count (to include body text and figure legends), number of references, and number of figures and/or tables
    • Abstract (double-spaced as part of manuscript file)
    • Article proper (double-spaced)
    • Acknowledgments, if any
    • References (double-spaced on a separate page of the manuscript file)
    • Figure legends (double-spaced on a separate page of the manuscript file)

    • Tables (uploaded separately as .doc files for revised submissions)
    • Figures (uploaded as separate files in .eps, .tif, or .jpg for revised submissions)
    • Supplementary Material and/or Videos, properly formatted (uploaded as separate files)

    •Signed permission to reproduce any previously published material, in all forms and media (scanned in as a file and uploaded as Permission)
    • Signed permission from person(s) named in Acknowledgments (scanned in as a file and uploaded as Permission)
    • Authorship agreement form (revised submissions)
    For any further information please visit our customer support site at http://support.elsevier.com.

    Editorial decisions and peer review

    Editorial decisions
    REJECT WITH INTERNAL REVIEW: Manuscripts may be rejected based on an internal editorial review if the manuscript does not fit the scope of the journal or did not achieve a sufficient score considering originality, reproducibility, and/or initial quality to be sent to external reviewers.
    REVISE: Authors are expected to address the concerns of the Editor and the reviewers in a constructive way. A request to submit a revised manuscript does not guarantee its acceptance only that it will be reconsidered by the same editor. Revised manuscripts should be submitted by or before the deadline specified in the letter; authors may request an extension to the deadline if needed.
    REJECT WITH HOPE: The manuscript is promising, but it requires significant modifications and/or additional experimental work. Authors can decide whether to submit a new version of the topic to the journal; the new version cannot be resubmitted earlier than 60 days from the date of the decision, but otherwise there is no deadline for submission. These new manuscripts should be accompanied by a unique file (separate from the cover letter and the body of the text) addressing previous reviewers’ comments. NOTE: Nanomedicine: NBM does not have minor and major revision categories, only REVISE. In the case of “REJECT WITH HOPE” decision the copyright goes back to the authors and they can elect to whether consider the comments and submit a new manuscript of the same topic to Nanomedicine NBM, or go to another journal. RwH manuscripts of the same topic that are sent to us again, are new manuscripts and all requirements for a new submission apply including processing fee. These manuscripts may or may not go back to the same editor and/or to the same reviewers, although the editors are provided with the responses in your renewed manuscript.
    REJECT: Manuscripts may be rejected if it does not fulfill all the requirements of the journal. Manuscripts with REJECT decisions (except for REJECT WITH HOPE) will not be reconsidered and should not be resubmitted to the Journal. Generally, these manuscripts are recommended for submission elsewhere.
    ACCEPT: The manuscript is accepted for publication and is sent to production.

    Peer review
    The purpose of the peer-review is to advise the editors regarding the value, originality, and significance of the manuscript.
    All manuscripts will be first evaluated for adherence to submission guidelines, assessed by the editors for originality and initial quality, and may then undergo a peer-review process at the discretion of the editors. Reviewers evaluate strengths and weaknesses of the work, but provide only advice. Identified weaknesses must be addressed i.e., accepted and corrected, or may be argued by the authors. Evaluation of any manuscript is based on its actual content, and responding to peer-review may not immediately be sufficient to earn publication. Provisional or final acceptance is based on scope, originality, scientific merit, relevance, reproducibility, clarity, and topical balance of the Journal.
    Editors may make a justified decision at any point of the review process. However, when peer review is solicited, at least two critiques are required. Final decisions are made by two editors and are communicated to the corresponding author by e-mail.

    Use of the Digital Object Identifier

    The Digital Object Identifier (DOI) may be used to cite and link to electronic documents. The DOI consists of a unique alpha-numeric character string which is assigned to a document by the publisher upon the initial electronic publication. The assigned DOI never changes. Therefore, it is an ideal medium for citing a document, particularly 'Articles in press' because they have not yet received their full bibliographic information. Example of a correctly given DOI (in URL format; here an article in the journal Physics Letters B):
    http://dx.doi.org/10.1016/j.physletb.2010.09.059
    When you use a DOI to create links to documents on the web, the DOIs are guaranteed never to change.

    Online proof correction

    Authors should carefully check all proofs, as it is their responsibility to see that all errors are corrected and queries answered. The authors have final responsibility for the accuracy of the publication.
    Corresponding authors will receive an e-mail with a link to our ProofCentral system, allowing annotation and correction of proofs online. The environment is similar to MS Word: in addition to editing text, you can also comment on figures/tables and answer questions from the Copy Editor. Web-based proofing provides a faster and less error-prone process by allowing you to directly type your corrections, eliminating the potential introduction of errors.
    If preferred, you can still choose to annotate and upload your edits on the PDF version. All instructions for proofing will be given in the e-mail we send to authors, including alternative methods to the online version and PDF. We will do everything possible to get your article published quickly and accurately - please upload all of your corrections within 48 hours. It is important to ensure that all corrections are sent back to us in one communication. Please check carefully before replying, as inclusion of any subsequent corrections cannot be guaranteed. Proofreading is solely your responsibility. Note that Elsevier may proceed with the publication of your article if no response is received.

    Offprints

    The corresponding author, at no cost, will be provided with a PDF file of the article via e-mail (the PDF file is a watermarked version of the published article and includes a cover sheet with the journal cover image and a disclaimer outlining the terms and conditions of use). For an extra charge, paper offprints can be ordered via the offprint order form which is sent once the article is accepted for publication. Both corresponding and co-authors may order offprints at any time via Elsevier's WebShop (http://webshop.elsevier.com/myarticleservices/offprints). Authors requiring printed copies of multiple articles may use Elsevier WebShop's 'Create Your Own Book' service to collate multiple articles within a single cover (http://webshop.elsevier.com/myarticleservices/booklets).

    Meeting information

    MEETING INFORMATION (announcements regarding upcoming nanomedicine conferences) and MEETING SUMMARIES will be posted on www.nanomedjournal.com separately from the scientific contents of the Journal.

    Other resources for authors

    How to Get Published: downloadable guide at
    http://www.elsevier.com/wps/find/authors.authors/authorpacks
    How to Write a Scientific Article:
    http://www.elsevier.com/framework_authors/pdfs/2_How_to_write_a_scientific_article_Author_Pack.pdf



    You can track your submitted article at http://help.elsevier.com/app/answers/detail/a_id/89/p/8045/. You can track your accepted article at http://www.elsevier.com/trackarticle. You are also welcome to contact Customer Support via http://support.elsevier.com.

    Last updated September 2014

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