Editorial Policies
The Journal of the American Society of Hypertension publishes peer-reviewed articles on the topics of basic, applied, and translational research on blood pressure, hypertension, and related cardiovascular, vascular, and renal disorders and factors. Original research studies, reviews, hypotheses, editorial commentary, and special reports spanning the spectrum of human and experimental animal and tissue research will be considered. All research studies involving animals must have been conducted following animal welfare guidelines such as the National Institutes of Health (NIH) Guide for the Care and Use of Laboratory Animals, or equivalent documents. Studies involving human subjects or tissues must adhere to the Declaration of Helsinki and Title 45, US Code of Federal Regulations, Part 46, Protection of Human Subjects, and must have received approval of the appropriate institutional committee charged with oversight of human studies. Informed consent must be obtained.

Manuscript Submission
Original works will be accepted with the understanding that they are contributed solely to the Journal, are not under review by another publication, and have not previously been published except in abstract form. Accepted manuscripts become the sole property of the Journal and may not be published elsewhere without the consent of the Journal. A form stating that the authors transfer all copyright ownership to the Journal will be sent from the Publisher when the manuscript is accepted; this form must be signed by all authors of the article.

All manuscripts must be submitted through the Journal of the American Society of Hypertension's online submission and review website (http://ees.elsevier.com/jash/ ). Submission items include a cover letter (required), the manuscript (required), and any figures and tables. Revised manuscripts should be accompanied by a unique file (separate from the cover letter) that provides responses to the reviewers' comments. The preferred order for uploading files is as follows: cover letter, response to reviewers (revised manuscripts only), manuscript file(s), table(s), figure(s). Files should be labeled with appropriate and descriptive file names (e.g., SmithText.doc, Fig1.eps, Table3.doc).

Text, tables, and figures should be uploaded as separate files. (Multiple figure files can be compressed into a Zip file and uploaded in one step; the system will then unpack the files and prompt the naming of each figure. See www.WinZip.com for a free trial.) Figures and tables should not be imported into the text document. Text and tables must be submitted as Word files. Complete instructions for electronic artwork submission, including acceptable file formats, can be found on the Author Gateway, accessible through the Journal home page (www.ashjournal.com). Figures will be tested by an artwork quality check tool and authors asked to view the results before the submission can be completed. Figures can be forwarded for manuscript review if not up to production standards, but high-quality figures are required if the manuscript is accepted for publication.

Authors who are unable to provide an electronic version or have other circumstances that prevent online submission must contact the Editorial Office prior to submission to discuss alternate options (jash@ash-us.org).

Cover Letter
The cover letter should be saved as a separate file for upload. In it, the authors should (1) state that the manuscript, or parts of it, have not been and will not be submitted elsewhere for publication; (2) state that all authors have read and approved the manuscript; and (3) disclose any financial or other relations that could lead to a conflict of interest. If a potential conflict exists, its nature should be stated for each author. When there is a stated potential conflict of interest a footnote will be added indicating the author's equity interest in or other affiliation with the identified commercial firms.

All sources of financial support for the study should be stated in the cover letter, including federal or state agencies, nonprofit organizations, and pharmaceutical or other commercial sources.

Manuscript Preparation
Title Page
The title page should include (1) a brief and descriptive title of the article, (2) a short title of less than 65 characters with spaces, (3) the authors' names, academic degrees, and hospital and academic affiliations, (4) acknowledgment of grants and other support, (5) a word count, (6) the number of figures and tables, and (7) the name and address (including zip code), telephone, fax, and email address of the individual responsible for editorial correspondence and proofreading.

All authors must disclose any financial or other relations that could lead to a conflict of interest. If a potential conflict exists, its nature should be stated for each author. When there is a stated potential conflict of interest a footnote will be added indicating the author's equity interest in or other affiliation with the identified commercial firms.

All sources of financial support for the study should be cited on the title page, including federal or state agencies, nonprofit organizations, and pharmaceutical or other commercial sources.

Abstract
The article should include a brief abstract of no more than 200 words. The abstract should be structured with the following headings: Background, Methods and Results, and Conclusions. The Background section should describe the rationale for the study. Methods and Results should briefly describe the methods and present the significant results. Conclusions should succinctly state the interpretation of the data.

Key Words
Authors should supply a list of up to four key words not appearing in the title, which will be used for indexing. The key words should be listed immediately after the Abstract.

Text
The text of original research papers should be organized as follows: Introduction, Methods, Results, Discussion. The Introduction should describe the purpose of the study and its relation to previous work in the field; it should not include an extensive literature review. Methods should be concise but sufficiently detailed to permit repetition by other investigators. Previously published methods and modifications should be cited by reference. Results should present positive and relevant negative findings of the study, supported when necessary by reference to tables and figures. The Discussion should interpret the results of the study, with emphasis on their relation to the original hypotheses and to previous studies. The importance of the study and its limitations should also be discussed.

Reviews, Hypotheses, and State-of-the Art papers should be organized as follows: Introduction, other appropriate subject headings, Conclusion. The Editor invites brief Letters to the Editor commenting on papers appearing in the Journal and on other issues.

Acknowledgments
Acknowledgment of those who contributed to the research or preparation of the paper should follow the text.

References
References should be double-spaced in numerical sequence according to standard Vancouver style, using Index Medicus abbreviations for journal titles. The first six authors should be listed in each reference citation (if there are more than six authors, "et al" should be used following the sixth). Periods are not used in authors' initials or journal abbreviations.

Journal Article
McClean D, Aragon J, Jamali A, Kar S, Ritzema-Carter J, Troughton R, et al. Noninvasive calibration of cardiac pressure transducers in patients with heart failure: an aid to implantable hemodynamic monitoring and therapeutic guidance. J Cardiac Fail 2006;12:568-76.

Book
Topol EJ. Textbook of interventional cardiology. Philadelphia: WB Saunders, 1999.

Chapter in Edited Book
Schiffrin EL, Intengan H. Remodeling of resistance arteries in hypertension. In: Weber MA, Oparil S, editors. Hypertension, 2nd ed. Philadelphia: WB Saunders, 2005. p 132-6.

References should be typed in parentheses and cited in numerical order in the text and listed at the end of the article in citation order. References to unpublished materials or personal communications should be cited in the text in parentheses and include relevant researchers. Further information about Vancouver reference style is available at www.icmje.org.

Figures and Legends
All figures should be cited in the text and numbered in order of appearance. Figures should be uploaded as individual files and named accordingly (ie, Figure 1.tiff, Figure 2.tiff) They should be saved in either tiff or eps file formats only, PowerPoint files will be sent back to the author. Color illustrations are not accepted for print publication unless the author agrees to pay all costs associated with producing color art. The cost is $650 per page of color illustrations. However, all illustrations submitted in color will be published in color online, at no cost to the author.

Legends should be supplied for each figure and should be brief and not repetitive of the text. Any source notation for borrowed figures should appear at the end of the legend. The magnification of any photograph should be omitted unless it is not generally apparent (as in an electron photograph). Legends should be double-spaced on a separate page within the manuscript, with all abbreviations and symbols appearing on the illustration described.

Tables
Tables should be comprehensible without reference to the text and should not be repetitive of descriptions in the text. Every table should consist of two or more columns; tables with only one column will be treated as lists and incorporated into the text. All tables must be cited in the text and numbered in order of appearance. Tables should include a short title. Each table submitted should be double-spaced, each on its own page. Each table should be saved as its own file as a Word Document. Explanatory matter and source notations for borrowed tables should be placed in the table footnote.

Permissions
To use tables or figures borrowed from another source, permission must be obtained from the copyright holder, usually the publisher. Authors are responsible for applying for permission for both print and electronic rights for all borrowed materials and are responsible for paying any fees related to the applications of these permissions. This is necessary even if you are an author of the borrowed material. It is essential to begin the process of obtaining permission early, as a delay may require removing the copyrighted material from the article. The source of a borrowed table should be noted in a footnote and of a borrowed figure in the legend. It is essential to use the exact wording required by the copyright holder. A copy of the letter granting permission, identified by table or figure number, should be sent along with the manuscript. A permission request form is provided for the authors use in requesting permission from copyright holders.

Page Proofs
Page proofs are sent from the Publisher electronically and must be returned within 48 hours to avoid delay of publication. Reprints are ordered from the Publisher at the time page proofs are returned.

Open Access
This journal offers you the option of making your article freely available to all via the ScienceDirect platform. To prevent any conflict of interest, you can make this choice only after receiving notification that your article has been accepted for publication. The fee of $3,000 excludes taxes and other potential author fees such as color charges. In some cases, institutions and funding bodies have entered into agreement with Elsevier to meet these fees on behalf of their authors. Details of these agreements are available at http://www.elsevier.com/fundingbodies. Authors of accepted articles who wish to take advantage of this option should complete and submit the order form (available at http://www.elsevier.com/locate/openaccessform.pdf). Whatever access option you choose, you retain many rights as an author, including the right to post a revised personal version of your article on your own website. More information can be found here: http://www.elsevier.com/authorsrights.

AUTHOR'S CHECKLIST When submitting manuscripts to the Journal of the American Society of Hypertension please remember to include the following:

Cover Letter

• The authors should (1) state that the manuscript, or parts of it, have not been and will not be submitted elsewhere for publication; (2) state that all authors have read and approved the manuscript; and (3) disclose any financial or other relations that could lead to a conflict of interest. If a potential conflict exists, its nature should be stated for each author.
• All sources of financial support for the study should be stated including federal or state agencies, nonprofit organizations, and pharmaceutical or other commercial sources.
• Manuscript, including
  - Title page
  - Article title
  - Short title (less than 65 characters w/ spaces)
  - Authors' names, academic degrees, affiliations
  - Acknowledgment of grants and other financial support
  - Word count
  - Number of figures and tables
  - Name, address, telephone, fax, and email address of corresponding author
  - All authors must disclose any financial or other relations that could lead to a conflict of interest. If a potentional conflict exists, its natureshould be stated for each author. When there is a stated potential conflict of interest a foote note will be added indicating the author's equity interest in or other affiliation with the identified commercial firms.
  - All sources of financial support for the study should be stated including federal or state agencies, nonprofit organizations, and pharmaceutical or other commercial sources.
• Abstract
• Key words
• Text
• Acknowledgments
• References

Ashley Buron, Managing Editor
Journal of the American Society of Hypertension
45 Main Street, Suite #712
Brooklyn, NY 11201
Tel: 212-696-9099
Fax: 347-916-0267
E-mail: jash@ash-us.org