Guide for Authors

  • The Journal of Experimental and Clinical Medicine (JECM) aimsto publish high quality scientific research in the field of experimentaland clinical medicine, with the goal of promoting anddisseminating medical science knowledge to improve globalhealth.

    Articles on clinical, laboratory and social research in medicineand other related fields that are of interest to the medicalprofession are eligible for consideration. The JECM publishes special issues,review articles, original articles, short communications,and letters to the editor. The journal is published online ( 2 months, with a total of 6 issues a year.

    The Editorial Board requires authors to be in compliancewith the Uniform Requirements for Manuscripts Submitted toBiomedical Journals (URMs); current URMs are available at

    1. Manuscript Submission

    1.1. Online Submission

    Manuscripts (meaning all submission items, including all text, tables, artwork, cover letter, authorship statement and conflicts of interest disclosures, and any other required documents/material) must be submitted online to the JECM through the Elsevier Editorial System (EES) at If assistance is required, please refer to the tutorials for authors and/or customer support that are available on the EES website; you may also contact the Editorial Office. Please do not post, fax or e-mail your manuscripts to the Editorial Office.

    Editorial Office
    Journal of Experimental and Clinical Medicine
    Taipei Medical University
    250, Wu-Hsing Street
    Taipei, Taiwan 110
    Tel: +886 2 27361661 ext. 7196
    Fax: +886 2 27391797

    Important information

    • Articles submitted should be in Microsoft Word documentformat and prepared in the simplest form possible. Wewill add in the correct font, font size, margins and so onaccording to the journal's style.
    • You may use automatic page numbering, but do NOT useother kinds of automatic formatting such as footnotes,endnotes, headers and footers.
    • Put text, references, and table/figure legends in one file.
    • For the purposes of peer review, please submit your figures in a PowerPoint file. However, should your manuscript be accepted for publication, figures must then be submitted as separate picture files, at thecorrect resolution of a minimum of 600 dpi. The files shouldbe named according to the figure number and format,e.g., "Fig1.tif", "Fig2.jpg".

    Please ensure that the following documents are included (referalso to the checklist that follows these author instructions):

    (1) Cover Letter. It must include your name, address, telephoneand fax numbers, and e-mail address, and statethat all authors have contributed to the paper and havenever submitted the manuscript, in whole or in part, toother journals. Your signature and those of ALL yourcoauthors must be included.

    (2) Authorship & Conflicts of Interest Statement. Each author¡¦s contribution to the manuscript should be listed. Any and all potential and actual conflicts of interest should also be listed (see Section 2 for more information). Please use the JECM Authorship & Conflicts of Interest Statement form that follows these author instructions. Your signature and those of ALL your coauthors must be included.

    (3) Copyright Transfer Agreement. You may use the formthat follows these author instructions.

    (4) Ethics Statement. Articles covering the use of human or animal samples in research, or human or animal experiments must be accompanied by a letter of approval from the relevant review committee or authorities. See Section 3 for more information.

    (5) Signed Statement of Informed Consent. Articles where human subjects can be identified in descriptions,photographs or pedigrees must be accompaniedby a signed statement of informed consent to publish(in print and online) the descriptions, photographs andpedigrees from each subject who can be identified. See Section 4 for more information.

    (6) Copyright Permission. If you have reproduced or adapted material from other copyrighted sources, the letter(s) of permission from the copyright holder(s) to reproduce or adapt the copyrighted sources must be supplied. Otherwise, such material must be removed from your manuscript.

    2. Disclosure of Conflicts of Interest

    A conflict of interest occurs when an individual¡¦s objectivity is potentially compromised by a desire for financial gain, prominence, professional advancement or a successful outcome. JECM Editors strive to ensure that what is published in the Journal is as balanced, objective and evidence-based as possible. Since it can be difficult to distinguish between an actual conflict of interest and a perceived conflict of interest, the Journal requires authors to disclose all and any potential conflicts of interest.

    Conflicts of interest may be financial or non-financial. Financial conflicts include financial relationships such as honoraria; educational grants; participation in speakers¡¦ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; expert testimony or patent-licensing arrangements. Non-financial conflicts include personal or professional relationships, affiliations, academic competition, intellectual passion, knowledge or beliefs that might affect objectivity.

    Please ensure that the name of each author listed in your manuscript appears in either Section I or Section II on page 2 of the JECM Authorship & Conflicts of Interest Statement form (an author¡¦s name cannot appear in both Section I and Section II of the form)

    3. Ethical Approval of Studies and Informed Consent

    For human or animal experimental investigations, appropriateinstitutional review board or ethics committee approval isrequired, and such approval should be stated in the methodssection of the manuscript. For those investigators who donot have formal ethics review committees, the principles outlinedin the Declaration of Helsinki should be followed (WorldMedical Association. Declaration of Helsinki: ethical principles formedical research involving human subjects. Available at: ).

    For investigation of human subjects, state explicitly in themethods section of the manuscript that informed consentwas obtained from all participating adult subjects and fromparents or legal guardians for minors or incapacitated adults,together with the manner in which informed consent wasobtained (i.e., oral or written).

    For work involving animals, the guidelines for their care and use that were followed should be stated in the methods section of the manuscript. For those investigators who do not have formal institutional guidelines relating to animal experiments, the European Commission Directive 86/609/EEC for animal experiments (available at should be followed and the same should be stated in the methods section of the manuscript.

    4. Identification of Patients in Descriptions,Photographs and Pedigrees

    A signed statement of informed consent to publish (in printand online) patient descriptions, photographs and pedigreesshould be obtained from all subjects (parents or legal guardiansfor minors) who can be identified (including by thesubjects themselves) in such written descriptions, photographsor pedigrees. Such persons should be shown themanuscript before its submission. Omitting data or making data less specific to de-identify patients is acceptable, butchanging any such data is not acceptable. State explicitly in the methods section of the manuscript that informed consent was obtained from all participating adult subjects or from parents or legal guardians for minors or incapacitated adults, together with the manner in which informed consent was obtained (i.e., oral or written).5. Previous Publication or Duplicate Submission

    Submitted manuscripts are considered with the understandingthat they have not been published previously in printor electronic format (except in abstract or poster form) andare not under consideration in totality or in part by anotherpublication or electronic medium. The retraction policy will be enforced if there is any evidence of scientific misconduct.

    6. Basic Criteria

    Articles should be written in English (using American Englishspelling) and meet the following basic criteria: the material isoriginal, the information is important, the writing is clear andconcise, the study methods are appropriate, the data are valid,and the conclusions are reasonable and supported by the data.

    7. Categories of Articles

    7.1. Review Articles
    These should aim to provide the reader with a balanced overviewof an important and topical subject in the field, and shouldbe systematic and critical assessments of literature and datasources. They should cover aspects of a topic in which scientificconsensus exists as well as aspects that remain controversialand are the subject of ongoing scientific research. All articlesand data sources reviewed should include information aboutthe specific type of study or analysis, population, intervention,exposure, and tests or outcomes. All articles or data sourcesshould be selected systematically for inclusion in the reviewand critically evaluated. The text should not exceed 4500 words.By invitation only. The format for review articles will be jointlydecided by the Editors and the contributing author.

    7.2. Original Articles
    These articles typically include randomized trials, interventionstudies, studies of screening and diagnostic tests, laboratoryand animal studies, cohort studies, cost-effectiveness analyses,case-control studies, and surveys with high response rates,which represent new and significant contributions to the field.

    Section headings should be: Abstract, Introduction,Methods, Results, Discussion, Acknowledgments (if applicable)and References.

    The Introduction should provide a brief background to thesubject of the paper, explain the importance of the study, andstate a precise study question or purpose.

    The Methods section should describe the study designand methods (including the study setting and dates, patients/participants with inclusion and exclusion criteria, or datasources and how these were selected for the study, patientsamples or animal specimens used, explain the laboratory methodsfollowed), and state the statistical procedures employedin the research.

    The Results section should comprise the study results presentedin a logical sequence, supplemented by tables and/orfigures. Take care that the text does not repeat data that arepresented in tables and/or figures. Only emphasize and summarizethe essential features of any interventions, the mainoutcome measures, and the main results.

    The Discussion section should be used to emphasize thenew and important aspects of the study, placing the resultsin context with published literature, the implications of thefindings, and the conclusions that follow from the study results.

    The text should not exceed 3500 words.

    7.3. Letters to the Editor
    LThis article category is a forum for rapid interactions and discussions between readers and authors. Letters are welcome not only in response to previously published articles, but may also include interesting clinical cases and other communications of general interest between clinical and basic biomedical scientists. Any breakthrough new biomedical idea should be disclosed promptly in a Letter to the Editor. Julius Axelrod shared the 1970 Nobel Prize, based primarily on a 2-page letter to Science to report a breakthrough new idea regarding the inhibition of re-uptake of catecholamines. Moreover, Professors Ignarro and Murad shared the Nobel Prize by publishing their new idea regarding EDRF in the FASEB annual meeting proceedings 4 months prior to Professor Moncade's full article in Nature. It is hoped that the Letters in JECM may help someone to win awards.

    Letters should have a concise title and not more than 5 references, followed by the author names and affiliations. The corresponding author's mailing and e-mail addresses should be listed at the end of the letter. A letter may include 1 figure, and the main text should not exceed 850 words, and thus letters are edited, sometimes extensively, to sharpen their view points. They may be sent for peer review at the discretion of the Editors. Letters are selected based on significance and space.

    7.4. Short Communications
    These reports should be concise presentations of clinical orpreliminary experimental results. The abstract should notexceed 150 words. The text should not exceed 1200 words,with no more than four figures or tables and no more than10 references. The editors reserve the right to decide whatconstitutes a Short Communication.

    8. Manuscript Preparation

    Text should be typed double-spaced on one side of white A4(297 x 210 mm) paper, with outer margins of 2.5 cm. A manuscriptshould include a title page, abstract, text, references,acknowledgments, and figures and tables as appropriate.Each section of the manuscript should begin on a new page.Pages should be numbered consecutively, beginning withthe title page.

    8.1. Title Page
    The title page should contain the following information(in order, from the top to bottom of the page):

    • category of paper
    • article title
    • names (spelled out in full) of all authors*, and the institutionswith which they are affiliated
    • corresponding author details (name, e-mail, mailing address,telephone and fax numbers)
    • running title not exceeding 50 characters

    *The name of each author should be written with the family namelast, e.g., Jing-Long Huang. Authorship is restricted only to directparticipants who have contributed significantly to the work.

    8.2. Abstracts and Key Words
    Abstracts should be no more than 300 words in length.Abstracts for Original Articles should be structured, with thesection headings: Background/Introduction, Purpose(s)/Aim(s),Methods, Results, Conclusion. Abstracts for Case Reports areunstructured, but should include the significance and purposeof the case presentation, the diagnostic methods of the case,the key data, and brief comments and suggestions with regardto the case. For all article categories, 3-5 relevant key wordsshould also be provided in alphabetical order.

    8.3. Main Text
    The text for Original Articles should be organized in sectionsas follows: Background/Introduction, Purpose(s)/Aim(s),Methods, Results and Discussion. Each sectionshould begin on a new page.

    8.3.1. Abbreviations
    Where a term/definition will be continually referred to, it mustbe written in full when it first appears in the text, followed bythe subsequent abbreviation in parentheses. Thereafter, theabbreviation may be used. Restrict the number of abbreviationsto those that are absolutely necessary.

    8.3.2. Units
    Système International (SI) units must be used, with the exceptionof blood pressure values which are to be reported in mmHg.Please use the metric system for the expression of length,area, mass, and volume. Temperatures are to be given in degreesCelsius.

    8.3.3. Names of Drugs, Devices and Other Products
    The generic term should be used, unless the specific tradename is directly relevant to the discussion.

    8.3.4. Statistical Requirements
    Statistical analysis is essential for all research papers exceptcase reports. A p value of < 0.05 is considered statistically significant. Use correct nomenclature of statistical methods(e.g., two sample t test, paired t test). Descriptive statistics shouldfollow the scales used in data description. Inferential statisticsare important for interpreting results and should bedescribed in detail.

    8.3.5. Acknowledgments
    General acknowledgments for consultations, statistical analysis,etc., should be listed concisely at the end of the text,including the names of the individuals who were directlyinvolved. Consent should be obtained from those individualsbefore their names are listed in this section.

    All financial and material support for the research andwork from internal or external agencies, including commercialcompanies, should be clearly and completely identified.Ensure that any conflicts of interest are explicitly declared.

    8.4. References

    8.4.1. In the Main Text, Tables, Figure Legends

    • References should be identified using superscripted numbers,and numbered consecutively in order of appearancein the text and placed after punctuation.
    • References cited in tables or figure legends should beincluded in sequence at the point where the table or figureis first mentioned in the main text.
    • Do not cite uncompleted work or work that has not yet beenaccepted for publication (i.e., "unpublished observation","personal communication") or non-peer reviewed web pages or information as references.
    • Do not cite abstracts unless they are the only availablereference to an important concept.

    8.4.2. In the References Section
    • References should be limited to those cited in the textand listed in numerical order, NOT alphabetical order.
    • References should include, in order, author names, articletitle, journal name, year, volume and inclusive page numbers.The last names and initials of all the authors up to 7should be included, but when authors number 8 or more,list the first 7 authors only followed by "et al".
    • Abbreviations for journal names should conform to thoseused in MEDLINE.
    • If citing critical information from a website, provide the author information, article title, website address and the date you accessed theinformation. However, if citing non-peer reviewed information from a website, the website address and date you accessed it should be provided in the main text and not listed in the References.
    • Reference to an article that is in press must state thejournal name and, if possible, the year and volume.

    Authors are responsible for the accuracy and completeness oftheir references and for correct text citation.

    Examples are given below.

    Standard journal article
    Chen Z, Fan M, Bian Z, Zhang Q, Zhu Q, Lu P. Immunolocalizationof heat shock protein 70 during reparative dentinogenesis.Chin J Dent Res 2000;3:50-5.

    Journal supplement
    Kaplan NM. The endothelium as prognostic factor and therapeutictarget: what criteria should we apply? J CardiovascPharmacol 1998;32(Suppl 3):S78-80.

    Journal article not in English but with English abstract
    Kawai H, Ishikawa T, Moroi J, Hanyu N, Sawada M, KobayashiN, Mutou T, et al. Elderly patient with cerebellar malignantastrocytoma. No Shinkei Geka 2008;36:799-805. [In Japanese,English abstract]

    Bradley EL. Medical and Surgical Management. Philadelphia:Saunders, 1982:72-95.

    Book chapter in book with editor and edition
    Greaves M, Culligan DJ. Blood and bone marrow. In:Underwood JCE, ed. General and Systematic Pathology, 4thed. London: Churchill Livingstone, 2004:615-72.

    Conference proceedings
    Pacak K, Aguilera G, Sabban E, Kvetnansky R, eds. Stress:Current Neuroendocrine and Genetic Approaches. 8th Symposiumon Catecholamines and Other Neurotransmitters inStress, June 28-July 3, 2003, Smolenice Castle, Slovakia. NewYork: New York Academy of Sciences, 2004.

    Ayers AJ. Retention of Resin Restorations by Means ofEnamel Etching and by Pins. MSD thesis, Indiana University,Indianapolis, 1971.

    American Association of Oral and Maxillofacial Surgeons.Wisdom Teeth. Rosemont, IL: AAOMS, 2008. Available at: [Date accessed:November 15, 2008]

    Company/manufacturer publication/pamphlet
    Eastman Kodak Company, Eastman Organic Chemicals.Catalog No. 49. Rochester, NY: Eastman Kodak, 1977:2-3.

    8.5. Tables
    Tables should supplement, not duplicate, the text. They shouldhave a concise table heading, be self-explanatory, and numberedconsecutively in the order of their citation in the text.Information requiring explanatory footnotes should bedenoted using these symbols (in order of appearance): *,†, ‡, §, ∥, ¶, #, **, ††, ‡‡, §§, etc. Abbreviations used in the table must bedefined and placed after the footnotes. If you include a blockof data or table from another source, whether published orunpublished, you must acknowledge the original source. Any one table should not exceed 8.5 x 8.5 cm in size.

    8.6. Figures
    The number of figures should be restricted to the minimumnecessary to support the textual material. They should havean informative figure legend and be numbered in the orderof their citation in the text. All symbols and abbreviationsshould be defined in the legend. Patient identification shouldbe obscured. All lettering should be done professionally andshould be in proportion to the drawing, graph or photograph.Photomicrographs must include an internal scale marker, thetype of specimen, original magnification and stain. Figures should not be larger than 8.5 x 8.5 cm in size.

    For the purposes of peer review, please submit your figures in a PowerPoint file. However, should your manuscript be accepted for publication, figures must then be submitted as separate picture files(e.g., TIF, JPG, etc.) at the correct resolution of a minimum of600 dpi. The files should be named according to the figurenumber and format, e.g., "Fig1.tif", "Fig2.jpg".9. The Editorial and Peer Review Process

    As a general rule, the receipt of a manuscript will be acknowledgedwithin 2 weeks of submission, and authors will beprovided with a manuscript reference number for future correspondence with a pre-screening editorial checklist.If such an acknowledgment is not received ina reasonable period of time, the author should contact theEditorial Office.

    Manuscripts are reviewed by the Editorial Office to ensurethat the submission contains all parts. The Editorial Office willnot accept a submission if the author has not supplied allparts of the manuscript as outlined in this document.

    Manuscripts are then forwarded to the Editor-in-Chief, whomakes an initial assessment of it. If the manuscript does notappear to be of sufficient merit or is not appropriate for theJournal, then the manuscript will be rejected without review.Rejected manuscripts will not be returned to authors unlessrequested.

    Manuscripts that appear meritorious and appropriate forthe Journal are reviewed by at least two Editorial Board membersor expert consultants assigned by the Editor-in-Chief.Authors will usually be notified within 10 weeks of whetherthe submitted article is accepted for publication, rejected, orsubject to revision before acceptance. However, do note thatdelays are sometimes unavoidable.

    10. Preparation for Publication

    Once a manuscript has been accepted for online publication, theauthors should submit the final version of their manuscriptthrough Elsevier's online submission system-EES.

    Accepted manuscripts are copyedited according to thejournal's style and the galley proofs in the form of a PDF fileare e-mailed by the Publisher to the corresponding author forfinal approval. Authors are responsible for all statements madein their work, including changes made by the copy editor.

    Proofreading is solely the authors¡¦ responsibility. The corresponding author should e-mail their revisions (if any; only minor revisions are allowed at this stage) and approval of the proofs to the Publisher within 48 hours. Note that the Editorial Board reserves the right to make revisions to the manuscript and the Publisher may proceed with the publication of your article if no response from the author(s) is received.

    10.1. Changes to Authorship
    This policy concerns the addition, deletion, or rearrangement of author names in the authorship of accepted manuscripts. Before the accepted manuscript is published online, requests to add or remove an author, or to rearrange the author names, must be sent to the Journal Manager from the corresponding author of the accepted manuscript and must include: (i) the reason the name should be added or removed, or the author names rearranged; and (ii) an updated Authorship & Conflicts of Interest Statement with signatures from all authors that they agree with the addition, removal or rearrangement. In the case of addition or removal of author names, this must include confirmation from the author(s) being added or removed. Requests that are not sent by the corresponding author will be forwarded by the Journal Manager to the corresponding author, who must follow the procedures as described above.
    Note that: (1) Journal Managers will inform the Journal Editors of any such requests and (2) online publication of the accepted manuscript is suspended until authorship has been agreed.
    After the accepted manuscript is published online, any requests to add, remove, or rearrange author names in an article will follow the same policies as detailed above and result in a corrigendum.

    11. Copyright

    The JECM is an official peer-reviewed publication of TaipeiMedical University, Taipei, Taiwan. Published manuscriptsbecome the permanent property of Taipei Medical Universityand may not be published elsewhere in any form withoutwritten permission.

    Updated on Jun 2014


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