PUBLICATION

The Journal of Cardiothoracic and Vascular Anesthesia will consider for publication suitable articles on all topics related to anesthesia for cardiac, vascular, and thoracic surgery. The scope of this Journal is broad and seeks to consolidate all material pertinent to cardiothoracic anesthesiology, including topics from critical care medicine, pharmacology, monitoring, perfusion technology, internal medicine, surgery, and transplantation.

Articles, editorials, letters to the Editor, and other text material in the Journal represent the opinion of the authors and do not necessarily reflect the opinion of the Editor, Editorial Board, or Publisher. The Editors and Publisher deny any responsibility or liability for statements and opinions expressed by the authors. Neither the Editor nor the Publisher guarantees, warrants, or endorses any product or service advertised in this publication, nor do they guarantee any claim made by the manufacturer of such product or service.

Authors submitting a manuscript do so with the understanding that if it is accepted for publication, copyright of the article, including the right to reproduce the article in all forms and media, shall be assigned exclusively to the Publisher. Following acceptance for publication, in order to comply with United States copyright law and the requirementsof the insurance carrier, the Publisher will requireauthors of accepted manuscripts and letters to sign a copyright release form.

SUBMISSION

All submissions must be directed to our web site: http://ees.elsevier.com/jcva. Offline submission is not permitted, unless requested by the Editorial Office. On the home page you will find links not only to this Guide, but also to a Tutorial for Authors, Artwork Guidelines, and general information on the Journal.

First-time Corresponding Authors can register from the home page by clicking on the register link. You will receive e mails guiding you on the basic information for submitting a manuscript. Each page of the web site during the review process contains important information for that step. The Editorial Office will send by e-mail only to the Corresponding Author all communications related to the status of a submission, including the final decision and the scheduled date of publication.

Detailed information on submissions is provided below. Further inquiries and information may be directed to the Editorial Office at: dwalk@louisville.edu.

EDITORIAL POLICIES

Manuscripts are accepted for consideration on the condition that they are contributed solely to the Journal of Cardiothoracic and Vascular Anesthesia. No substantial part of a paper may have been published elsewhere, except for a scientific abstract.

Manuscripts will be reviewed by the Editor in Chief, Section Editors, members of the Editorial Board, and appropriate guest reviewers. Acceptance of a paper for publication is based on the originality and quality of the observation or investigation and the clarity of the presentation. Clinically relevant material is especially desirable. Good English usage is an essential prerequisite for consideration of the paper.

In all cases the authors must accept the responsibility of conforming to the instructions in the sections below. Submissions must conform fully before reviewers will be assigned. Substantial non-conformity may result in outright rejection.

If a submitted article is accepted for publication, editorial revisions may be made to aid clarity and understanding without altering the meaning.

Electronic-only Publication. Letters to the Editor, the Cardiac Calendar, and selected articles from other sections (e.g., Case Reports, Diagnostic Dilemmas, and E-Challenges) are published E-ONLY. Like print articles, E-only articles will be indexed in Medline and elsewhere and will be included on the print issue's Table of Contents.

Experimentation subjects. Papers reporting human experimentation will be reviewed in accordance with the precepts established by the Helsinki Declaration (available at http://www.wma.net/en/30publications/10policies/b3/). Such papers must include a statement that human investigations were performed after approval by a local Human Investigations Committee and after obtaining informed consent from a patient or other responsible individuals. All experimental work with animals must conform to American Physiological Society Guiding Principles for the Care and Use of Vertebrate Animals in Research and Training (http://www.the-aps.org/pa/resources/policyStmnts/paPolicyStmnts_Guide.htm).

Article types. The following may be submitted: Original Research Articles, Case Reports, Review Articles, Emerging Technology Reviews, E-Challenges and Clinical Decisions, Case Conferences, Pro and Con Articles, Diagnostic Dilemmas, Special Articles (those not easily suited to another type), and Correspondence (letters to the Editor).Cardiac Anesthesia Fellows Education (CAFE) articles may be submitted by cardiac fellows and their mentors. The CAFE section is devoted to developing the clinical and publication skills of fellows. Articles for this section may be submitted as any of the above article types and may be augmented by expert commentaries. Case Conferences should be augmented by expert commentaries.Potential authors are invited to e-mail the Editorial Office to contact Editor in regard to interest in a proposed submission.

DETAILS ON ARTICLE TYPES

For examples of all article types, see any recent issue of the Journal.

For all submissions, each table, figure, or video/audio clip is to be included only as a separate Table, Figure, or Video/Audio Clip document, and is not to be placed in the Manuscript (main text) document. Video stills must be submitted as Figures.

Original Research Articles. This article type requires 4 documents: Cover Letter, Title Page, Structured Abstract, and Manuscript.The Structured Abstract is limited to 250 words (including section headings). The abstract should consist of 7 paragraphs:
1. Objective(s): What scientific question was the study designed to answer?
2. Design: A phrase describing whether a study is prospective, randomized, blinded, retrospective, etc.
3. Setting: Type of hospital or laboratory; university or community setting; single or multi-institutional.
4. Participants: Patients, volunteers, animals.
5. Interventions: What interventions were done to the participants?
6. Measurements and Main Results: How was the outcome of the intervention(s) assessed? What were the major finding(s) of interest?
7. Conclusions: What conclusion(s) may be reasonably drawn from the results of the study?

Following these 7 paragraphs, repeat the list of Key Words that you have uploaded onto the Key Word page. No references or abbreviations should be used in the abstract. The name or location of the authors’ institution should not be revealed.The Manuscript document must have 4 identified sections: Introduction, Methods, Results, and Discussion. A description of the statistical methods used should be included in the last part of the Methods section. The name or location of the authors' institution should not be revealed in this document.

Case Reports. This article type requires 4 documents: Cover Letter, Title Page, Summary, and Manuscript. The Manuscript document should begin with a short introduction to the clinical context of the case and follow with 2 identified sections: Case Report and Discussion. A 1-paragraph summary should complete the article. In most situations the introduction and final summary can be the basis for the Summary item.

Case Conferences. These articles are handled by a Section Editor for Case Conferences. Some offline communication between authors and editors may be required.

• A Case Conference comprises a Case Report with a Discussion and one or more experts commentaries that provide input from related specialties and/or viewpoint(s) on anesthetic or intensive care management of the case.
• A commentator needs to provide his or her full name, degrees, affiliation, and e-mail address. Commentators will be listed as authors.
• Figures, video clips, tables, and references from the case authors and commentators are desirable to expand the teaching value of the case. Follow the guidelines below for preparing figures, video clips, tables, and references.
• The final version of the Case Conference will have its references compiled into a single consecutively-numbered list.

Review Articles. Review articles may be invited by a Section Editor, but invitation is not necessary for full consideration. This article type requires 3 documents: Cover Letter, Title Page, and Manuscript. The scope and purpose of the review must be clearly defined and accomplished in the Manuscript document. Authors are encouraged to provide relevant table, figure, and video clip documents.

Diagnostic Dilemmas. This cogent article type is in two parts. First, it presents a case with difficult diagnosis, usually resulting from preliminary graphic evidence. The reader is then invited to project a tentative diagnosis. In the second part, the interpretation of futher imaging techniques or other investigation is provided to resolve the dilemma. High quality figures and/or video clips are vital for these submissions.

Letters to the Editor. A Cover Letter and a Title Page are needed separate from the Letter (Manuscript) item. The Letter to the Editor should be double-spaced, brief, and concisely focused. Cited works must have full, accurate references. Figures, video clips, and tables may be included. Letters to the Editor will be published only online.

MANUSCRIPT DETAILS

• All documents (except figures) should be prepared in Microsoft Word for Windows or a fully compatible program, not in .pdf or any graphic format.
• Manuscripts must be double-spaced throughout the document on page sizes 8½ x 11 inches or A4. A margin of about 1 inch (2.5 cm) should be provided on all sides. All type should be 11-13 points in size, except as appropriate in tables and figures. Page numbers are required on Manuscript (main text) documents. Landscape format is acceptable as needed to display tables or figures to advantage.
• Word limits are not imposed on any manuscript types, but allpapers should be concise, yet complete.
• All required or optional items for a submission are identified on the Attach Files page on the online submission form. Every table, figure, or video clip requires a separate electronic file; the "Description" column on the Attach Files page should provide the textual reference (e.g., 'Table 3'); this column is fully editable.
• No document can be submitted "offline."
• Use generic drug names throughout. Brand names may be inserted in parentheses following the generic names.
• The name and city/state/country of a drug or technology manufacturer must be included after the name of the product.
• The author(s) or the name or geographical location of an author's institution(s) must not be identified in the text, header, or footer in the submission except on the Title Page and the Cover Letter.
• Acknowledgments must be placed at the end of the Title Page, not in the Manuscript document.

ONLINE DOCUMENTATION

Online submission requires that the submitted material be uploadedin several separate files. Online instructions will clarify what files are required. Details on preparation of file types follow.

1. A Cover Letter addressed to the Editor in Chief. The letter must include at the end a list of all authors as if for signature. Cover letters scanned from official letterhead with all signatures are strongly encouraged. The cover letter must state that the authors agree with and are responsible for the data presented. The letter should also describe or deny any potential conflicts of interest including commercial relationships such as consultation and equity interests.
2. Title page with (a) title of paper; (b) authors' full names with advanced degrees; (c) name(s) and geographical location of institution(s) in which work was done; (d) description of research support, if any; (e) information on the corresponding author: full name and advanced degrees, a reliable e-mail address, complete street address (not only P.O. box), telephone and fax numbers, and (f) any personal acknowledgements.
3. For an Original Research article, a Structured Abstract; but for a Case Report, a Summary (max. 200 words to indicate the clinical context and significance of the case, recapitulate the essential features, its outcome, and likely consequences for further study or clinical practice). A Structured Abstract will be published; a Summary is not published but is circulated to invited reviewers.
4. Manuscript/main text The Figure Legend list should be provided after the list of references and double-spaced. The Figures should be followed by Video Clips in this list. Each legned should include a title, notes to gloss abbreviations, and a permission statement for use of any copyrighted materials. Titles and notes for tables should not be in this list. Automatic reference systems may be used but are not required. The first reference to each source must be in Arabic numerical order. The reference list at the end of the article must also be in numerical order. The list headed "REFERENCES" should begin on a new page of the Manuscript document and be double-spaced. Use NLM-recognized title abbreviations for periodicals throughout as available listed online at http://www.ncbi.nlm.nih.gov/journals . (based on those previously published by Index Medicus). References to abstracts, journal supplements, and letters to editors must be identified as such. Inclusive page numbers of references are required.Online references should be integrated numerically with the other media in the References list; do not submit them parenthetically or as footnotes.
5. Tables. A separate file is required for each table, including its number and title at the top and any notes at the end. The notes should provide definition of abbreviations used in the table and permission notices for use of copyrighted materials. Tables should be formatted as Microsoft Word tables or Excel spreadsheets, not in any graphic format. A table may be continued on multiple pages if necessary; do not repeat column headers on the additional pages.
6. Figures. A separate file is required for each figure, except for figures cited together and preferably to be seen adjacently (a-b etc.) It is strongly preferred that figures be submitted in .tif (300 dpi), .eps, or .pdf format. The highest possible quality is expected. Authors are responsible to meet the graphic standards in Publisher's Author Artwork Instructions ( http://www.elsevier.com/artworkinstructions).A link to these Instructions is also provided on the Journal's home page. Authors are strongly advised to consult these Instructions for detailed information before preparing figures.The Publisher automatically provides for every submission or revision an Artwork Quality Assessment to inform authors of any likely problems with their figures. Figures not properly prepared will be returned to the contributor for revision or will be reworked with the cost charged to the contributor.Color figures are acceptable for papers dealing with color imaging; however, as color printing is costly, it will be used at the discretion of the Editor. Color used in bar, line, and pie graphs is discoraged; please substitute distinct shades of gray and /or patterned lines and shapes. If color images are to be reproduced in black and white, the contributor should submit the prints in black and white for best results.
7. Video/audio clips. The preferred movie/video format is .mpg, and the preferred audio format is .mp3. For additional information, follow the link to Author Artwork Guidelines on the home page of this web site. Video stills must be submitted as Figures.

SAMPLE REFERENCES

Journal article, one to three authors
1. Beutler E: The effect of methemoglobin formation on sickle celldisease. J Clin Invest 40:1856-1858, 1961
2. Karpatkin S, Smith K, Charmatz A: Heterogeneity of humanplatelets. III. Glycogen metabolism in platelets of different sizes. Br JHaematol 19:135-137, 1970

Journal article, four or more authors
3. Golomb HM, Vardiman J, Sweet DL, et al: Hairy cell leukemia:Evidence for the existence of a spectrum of functional capabilities. Br JHaematol 38:161-162, 1968

Journal article in press
4. O'Malley JE, Eisenberg L: The hyperkinetic syndrome. SeminPsychiatry (in press)
(Note: A copy of the in-press article must be included as a Supplementary Manuscript file, described as "In-press, Reference [#].")

Complete book
5. Lillie RD: Histopathologic Technic and Practical Histochemistry(ed 4). New York, NY, Blakiston, 1965, pp 39-41

Chapter of book
6. Moore G, Minowada J: Human hemopoietic cell lines: A progressreport, in Farnes P (ed): Hemic Cells in Vitro, vol 4. Baltimore, MD,Williams & Wilkins, 1969, pp 100-105

Chapter of book that is part of published meeting
7. Hatvg JB, Kunkel HG, Gedde-Dahl T Jr: Genetic studies of theheavy chain sub-groups of gamma globulin, in Killander J (ed):Gamma Globulins, Proceedings of the Third Nobel Symposium. NewYork, NY, Wiley, 1967, pp 19-26

Chapter of book that is part of unpublished meeting
8. Polliak A: A morphologic study of the lymphoproliferative lesionsinduced by excess vitamin A. First Meeting, European Division,International Society of Hematology, Milan, Italy, 1971, p 181

Abstract
9. Curnutte JT, Karnovsky ML, Babior BM: Manganese-dependentNADPH oxidation by a particulate preparation from guinea pig granulocytes:An alternative interpretation. Clin Res 23:371A, 1975

Letter to Editor
10. Seeler RA: Sickle cell anemia monthly variations. Blood 47:879, 1976

PROOFREADING

Contributors are provided with electronic galley proofs and are expected promptly to proofread them for typesetting errors and to answer all queries. Important changes in data areallowed, but authors will be charged for excessive alterations in proof.

REPRINTS

Reprints of articles can be furnished to contributors when ordered inadvance of publication. An order form is sent in advance of proofs.Individuals wishing to obtain reprints of an article that appears in the Journal can do so bycontacting the author at the address given in the Journal. Electronic copies may be purchased from the Publisher.

CARDIAC CALENDAR

Announcements of meetings, conferences, and the like that are ofinterest to the readership of the Journal should be sent to the Section Editor for Cardiac Calendar,Dr. George Silvay (george.silvay@mountsinai.org), at least 3 monthsbefore the intended appearance of the notice. These announcements will be published only online.

Updated Sept. 2012