Guide for Authors

  • Fast, authoritative and in-depth reports
    Journal of Cardiology Cases (JC Cases) is an official peer-reviewed online journal of the Japanese College of Cardiology (JCC) dedicated to case reports. JC Cases provides an appropriate forum for all cardiologists by publishing without delay their important clinical cases of recent occurrence. Notable articles are also discussed in the journal's editorials. One year after their publication, all articles become accessible, at no cost, also to nonsubscribers.

    Learning from real cases
    Learning from medical cases provides valuable experience not only for clinicians, but also for students and paramedical staff members. Rare medical cases and conditions discovered through the latest methods of examination are often not found in textbooks, but frequently they are quickly reported in JC Cases. Encountering them early will greatly contribute to the acquisition of actual clinical capability by students and staff alike. Furthermore, learning diagnostic processes from medical cases and the interpretation of symptoms is important to train and develop thinking processes used in the clinical field.

    For all medical personnel
    This journal provides paramedical staff members also with opportunities to learn specifically about the role of examinations and ways to manage patients. Therefore JC Cases is the leading such case report journal and should be regularly read by all cardiovascular medical researchers, doctors, and medical personnel.

    From every clinical site
    The journal welcomes contributions from nonmembers of the Society. Please prepare manuscripts in conformance with the Uniform Requirements for Manuscripts Submitted to Biomedical Journals.

    JC Cases will receive materials prepared and submitted according to these instructions. However, we reserve the right to make any changes necessary to make the contribution conform to the editorial standards of the journal, as deemed by the Editorial Board based on the recommendations of the reviewers.

    Any contributions accepted for publication will become the copyright of this journal. No responsibility is assumed by the Editorial Board for the opinions or the ethics expressed by the contributors. The work shall not be published in any other publication in any language without prior written consent of the publisher.

    Manuscript submission

    Submission of an article is understood to imply that the article is original and is not being considered for publication elsewhere. Submission to JC Cases now proceeds online via Elsevier Editorial System— Authors will be guided step-by-step through uploading files directly from their computers. Electronic PDF proofs will be automatically generated from uploaded files, and used for subsequent reviewing.

    Authors submitting hard copy papers will usually be asked to resubmit using Elsevier Editorial System. The Editor-in-Chief may occasionally allow hard copy submissions of some components of an article; please contact him should you consider this necessary, and send any such items to:

    Editor-in-Chief, Journal of Cardiology Cases
    c/o Elsevier Japan, 1-9-15 Higashi-Azabu, Minato-ku, Tokyo 106-0044, Japan
    Tel: +81 3 3589 5037, Fax: +81 3 3589 6364

    Global telephone support is available for e-submission 24/7. A comprehensive Author Support service is also available to answer additional enquiries at

    For The Americas: +1 888 834 7287 (toll-free for US & Canadian customers)
    For Asia & Pacific: +81 3 5561 5032
    For Europe & rest of the world: +353 61 709190

    Copyright transfer

    Upon acceptance of the article by the journal, the author(s) will be asked to transfer the copyright of the article to the publisher. This transfer will ensure the widest possible dissemination of information.

    Multiple authorship

    All authors must have significantly contributed to and have finally approved the submitted article.

    Ethical standards

    Human subject experiments or the usage of human materials (such as tissues) should be in accordance with the ethical standards of a responsible committee at the institute where the research is carried out and with the Helsinki Declaration. Patients should be referred to by number; do not use real names, initials or hospital numbers. Animal studies should be carried out within recognised guidelines for the care of laboratory animals.

    For information on Ethics in publishing and Ethical guidelines for journal publication see and

    Conflict of interest

    All authors must disclose any financial and personal relationships with other people or organisations that could inappropriately influence (bias) their work. Examples of potential conflicts of interest include employment, consultancies, stock ownership, honoraria, paid expert testimony, patent applications/registrations, and grants or other funding. See also

    Article Types

    Case Reports: A case report should describe a new disease, or confirmation of a rare or new disease; a new insight into pathogenesis, etiology, diagnosis, or treatment; or a new finding associated with a currently known disease. The length should ordinarily be less than 1,500 words, with no more than a total of 3 tables and figures and 10 references. This can be exceeded only when justified by extensive special studies. Manuscripts should be written clearly in English.

    Letters to the Editor: These should be up to 1,000 words in length, and should be submitted in response to material published in the journal to make small clinical points or to introduce a point of view. They can be accompanied by up to 5 references but no illustrations.

    Editorial: The editors will solicit all editorials. Instructions pertaining to the writing of an editorial will be included with the request from the editorial office.

    General Preparation
    - All submissions should be prepared with the following files:
    Cover letter
    Authorship Agreement
    Tables (if any)
    Figures (if any)
    - Manuscripts should be double-spaced and include page numbers.
    - Manuscripts should including Title page, Abstract, Learning Objective, Text, Acknowledgments (if applicable), Conflict of interest, References, and Figure Legends.
    - Provide the Cover letter, Manuscripts and Tables files in Word format (.doc, .docx).

    Authorship Agreement
    When submitting a paper, authors must complete the Authorship Agreement form download from
    As of April 1st, 2014, the Authorship Agreement form has been updated.
    For all new submissions after April 1st, 2014, please use the new Authorship Agreement form.

    Cover Letter
    Manuscripts must be submitted with a cover letter stating that: 1) the paper is not under consideration elsewhere; 2) none of the paper's contents have been previously published; 3) all authors have read and approved the manuscript; and 4) the full disclosure of any relationship with industry. A short paragraph telling the editors why the authors think their paper merits publication priority may be included in the cover letter. Potential reviewers may be suggested in the cover letter, as well as reviewers to avoid.

    Preparing a manuscript

    Title page: All manuscripts must be covered with a title page including the following information:
    - Title of the article (within 25 words)
    - Every authors' full and complete names, degrees, and institutions
    - Corresponding author's Full name, postal address, e-mail, telephone and fax numbers
    - Up to 3-6 keywords or phrases suitable for use in an index.
    - Word count - excluding title page, abstract, references, figures and tables.

    Abstract: Within 200 words, briefly state in non-structured style a summary of the text, including background and purpose, methods and subjects, essential results, and principal conclusions. The abstract may be republished by information retrieval services in another forum.

    Learning objective: The learning objective should explain the educational value of this case report within 80 words. It is the take-home message and should be easily understood whether the report has or has not been read.
    Example: New drugs have become available for the specific treatment of pulmonary arterial hypertension. However, the treatment of portopulmonary hypertension (PoPH) has not been established. An acute vasoreactivity test of sildenafil may be useful for determining a choice of drugs in the treatment of PoPH.

    Introduction: Clearly and briefly describe the study's background and rational objective, with a review of earlier publications. It is recommended that previous studies described be only the most relevant. Avoid an exhaustive review of the literature.

    Case report: Clearly describe the subjects and sample size, the experimental procedures and apparatus (manufacturer's name and address) used in the study. In the case of experiments on human or animal subjects, give an account that the methods were regarded as ethically sound. In the event of an original design, the details should be provided. Otherwise, references accompanied by sufficient information for interdisciplinary evaluation will suffice. The type of statistical analysis used must be stated in this section as well as the commercial software. Do not include discussion in this section. Demonstrate precisely all drugs and chemicals used, including generic names, doses, and routes of administration. Present the essential results in the text in a clear and concise manner. Use tables and figures to compare and contrast the findings. Do not repeat in the text all the detailed data in the tables or figures. Do not include discussion in this section. In describing the statistical analysis, please define the probability values and prove that the differences reported were found to be statistically significant.

    Discussion: Demonstrate the objective reliability of the results as well as the propriety and limitations of the experimental procedures and subjects used. Point out the significance and the limitations of the study, including implications for future research. Describe and evaluate the results with a scientifically critical view, and discuss your findings in the context of other publications, including opposing views. The introduction or the details of the results should not be repeated in this section. Subjective comments can be made only in this section; however, speculation must be identified as such. Link the conclusions with the objectives of the study, as stated in the introduction.

    Acknowledgments: Acknowledgments, the scientific meeting at which the data has already been presented, the sources of funding for the study, and/or any other special mention may be stated before the References section.

    Conflict of interest: Authors must disclose all potential conflict of interest or state explicitly of its non-existence.

    References: All publications cited in the text should be presented in a list of references following the text of the manuscript. References should be numbered consecutively in the order in which they are first mentioned. In the text they should be cited with Arabic numerals between square brackets. For listing references, follow the Vancouver Style, abbreviating names of journals according to the list in PubMed. List all authors/editors but if there are more than fifteen, list first fifteen plus et al.


    [1] Matsumura K, Kubota S, Serizawa T, Nakase E. Coronary hemodynamics in vasospastic angina: Quantitative analysis by digital subtraction angiography. J Cardiol 1991;21:507–16 (in Japanese).
    [2] Braunwald E. Pathology of pulmonary embolism. In: Braunwald E, editor. Heart disease: A textbook of cardiovascular medicine. 5th ed. Philadelphia: WB Saunders; 1997. p. 1582–5.

    Figure Legends: Figure legends should be typed double-spaced, in numerical order, on a new page after References. Each figure legend should include a short title for the entire figure and descriptors for each panel. There should be sufficient experimental details in the legend to make the figure intelligible without reference to the text.
    Written permission must be obtained and supplied from the original author(s) and the original publisher (copyright holder) for the use of any figures, charts, graphs, and tables previously published in other journals or books either by reproduction or with any modification. Credit must be given in legends and/or text for borrowed materials.

    Tables: Tables should be submitted online as a separate file, bear a concise title, and be numbered with Arabic numerals. Tables should be cited in the text. Column headings should be brief, but sufficiently explanatory. Standard abbreviations of units of measurement should be added between parentheses. Vertical lines should not be used to separate columns.

    • The number of figures used to present data essential to illustrate or prove a point should be kept to a minimum.
    • Reference should be made in the text to each illustration. Figures will be reduced to fit to the size of one column (8.5 cm) or two columns (17.5 cm), and any lettering should be large enough to allow this reduction without becoming illegible.
    • Photographs should be as high in contrast as possible.
    • Indicate the magnification of photomicrographs in bar scales on the illustration itself instead of numerical magnification factors.
    • Make sure you use uniform lettering and sizing of your original artwork.
    • Save text in illustrations as "graphics" or enclose the font.
    • Only use the following fonts in your illustrations: Arial, Courier, Helvetica, Times, Symbol.
    • Number the illustrations according to their sequence in the text.
    • Use a logical naming convention for your artwork files.
    • Provide all illustrations as separate files.
    • Provide captions to illustrations separately.
    • Produce images near to the desired size of the printed version.

    A detailed guide on electronic artwork is available on our website:

    You are urged to visit this site; some excerpts from the detailed information are given here.

    File formats:

    Regardless of the application used, when your electronic artwork is finalised, please "save as" or convert the images to one of the following formats. Note the resolution requirements for line drawings, halftones, and line/halftone combinations given below.

    EPS: Vector drawings. Embed the font or save the text as "graphics".
    TIFF: Colour or greyscale photographs (halftones): always use a minimum of 300 dpi.
    TIFF: Bitmapped line drawings: use a minimum of 1000 dpi.
    TIFF: Combinations bitmapped line/half-tone (colour or greyscale): a minimum of 500 dpi is required.
    DOC, XLS or PPT: If your electronic artwork is created in any of these Microsoft Office applications please, supply "as is" (in native format).

    Please do not:

    • Supply embedded graphics in your wordprocessor (spreadsheet, presentation) document.
    • Supply files that are optimised for screen use (like GIF, BMP, PICT, WPG); the resolution is too low.
    • Supply files that are too low in resolution.
    • Submit graphics that are disproportionately large for the content.

    Colour illustrations:

    If, together with your accepted article, you submit usable colour figures, Elsevier will ensure that these figures will appear in colour completely free-of-charge in the electronic version of your paper.

    Supplementary data. JC Cases accepts electronic supplementary material such as high-resolution images, background datasets, sound clips, video material, animation sequences and more to support and enhance your scientific research and to evade the limit of manuscript length. Supplementary files supplied will be published online alongside the electronic version of your article. For more detailed instructions please visit our artwork instruction pages at Authors should submit the material as an e-component in electronic format together with the article and supply a concise and descriptive caption for each file.

    Video, animation and audio - Preferred specifications:

    To ensure that the majority of potential users are able to access, view and playback the data, Elsevier recommends the submission of material in the specified 'preferred' formats.


    MP3.mp3• MPEG-1 or MPEG-2 format required
    • Highest possible quality required
    If submitting audio, the following specifications are a guideline for authors/contributors
    • Audio Bit rate: at least 128 kbps


    MPG.mpg• MPEG-1 or MPEG-2 format required
    • Highest possible quality required
    MP4.mp4• Acceptable video format
    • Highest possible quality required
    Apple• Acceptable video format
    • Highest possible quality required
    Microsoft Audio/Video Interlaced format.avi• Acceptable video format
    • Highest possible quality required
    Compuserve GIF.gif• Expected to be nonphotographic animationbased data
    If submitting video, the following specifications are a guideline for authors/contributors
    • Frame rate: 15 frames per second minimum
    • NTSC (4:3) size and frame rate, de-interlaced
    • Video Codec: MPEG2 or MPEG4 (MPEG4 preferred)
    • Video Bit rate: at least 260 kbps (750 kbps preferred)
    • Resolution: 492×276 recommended
    • Time: no more than 5 minutes

    If the software used for the creation of your video(s)/animation(s) cannot deliver one of the above formats, then please save them in one of the accepted formats. Any alternative format supplied may be subject to conversion (if technically possible) prior to online publication.


    All contributions and all communications relating to the publication should be addressed to:

    Editor-in-Chief of Journal of Cardiology Cases
    c/o Elsevier Japan, 1-9-15 Higashi-Azabu, Minato-ku, Tokyo 106-0044, Japan
    Fax: +81 3 3589 6364, Tel:: +81 3 3589 5037, E-mail:

    Author rights

    As an author you (or your employer or institution) may do the following:

    - make copies (print or electronic) of the article for your own personal use, including for your own classroom teaching use
    - make copies and distribute such copies (including through e-mail) of the article to research colleagues, for the personal use by such colleagues (but not commercially or systematically, e.g., via an e-mail list or list server)
    - post a pre-print version of the article on Internet websites including electronic pre-print servers, and to retain indefinitely such version on such servers or sites
    - post a revised personal version of the final text of the article (to reflect changes made in the peer review and editing process) on your personal or institutional website or server, with a link to the journal homepage (on
    - present the article at a meeting or conference and to distribute copies of the article to the delegates attending such a meeting
    - for your employer, if the article is a "work for hire", made within the scope of your employment, your employer may use all or part of the information in the article for other intra-company use (e.g., training)
    - retain patent and trademark rights and rights to any processes or procedure described in the article
    - include the article in full or in part in a thesis or dissertation (provided that this is not to be published commercially)
    - use the article or any part thereof in a printed compilation of your works, such as collected writings or lecture notes (subsequent to publication of your article in the journal)
    - prepare other derivative works, to extend the article into book-length form, or to otherwise re-use portions or excerpts in other works, with full acknowledgement of its original publication in the journal

    Funding body agreements and policies

    Elsevier has established agreements and developed policies to allow authors who publish in Elsevier journals to comply with potential manuscript archiving requirements as specified as conditions of their grant awards. To learn more about existing agreements and policies please visit

    US National Institutes of Health (NIH) voluntary posting ("Public Access") policy

    Elsevier facilitates author response to the NIH voluntary posting request (referred to as the NIH "Public Access Policy"; see by posting the peer-reviewed author's manuscript directly to PubMed Central on request from the author, 12 months after formal publication. Upon notification from Elsevier of acceptance, we will ask you to confirm via e-mail (by e-mailing us at that your work has received NIH funding and that you intend to respond to the NIH policy request, along with your NIH award number to facilitate processing. Upon such confirmation, Elsevier will submit to PubMed Central on your behalf a version of your manuscript that will include peer-review comments, 12 months after formal publication. This will ensure that you will have responded fully to the NIH request policy. There will be no need for you to post your manuscript directly with PubMed Central, and any such posting is prohibited.

    Proofs and e-offprint (Print-version offprints are not supplied)

    Proofs will be sent to the corresponding author. If an e-mail address is supplied, proofs will be sent as e-mail attachment in PDF format, together with instructions. Authors are requested to return corrections by e-mail or fax within 48 hours. Authors will be charged for extensive alterations in the proofs. E-offprint (PDF) of each article will be supplied with no charge to the author.

    Journal of Cardiology Cases does not have page charges.


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