Author information pack

EuPA Open Proteomics is published by Elsevier on behalf of the European Proteomics Association (EuPA) and is aimed at both European and international protein scientists. It will publish on all aspects of proteomics and cover the complete spectrum from basic to translational proteomics, including bioinformatics and data processing. EuPA Open Proteomics will also accept direct submissions from authors wishing to report on large data sets (submitted to raw data repositories) and descriptive studies. Manuscripts are welcomed from plant, animal, microbial and human studies. All manuscripts are strictly peer reviewed and conform the highest ethical standards. EuPA Open Proteomics also publishes official EuPA reports and notes.

Types of paper

The following types of paper are published:

Original Articles: Original articles are the normal medium of publication. Although there is no fixed length, articles should be as concise as possible, while providing sufficient information for the work to be repeated and for the claims of the authors to be judged by the readers.

Mini-reviews: These are short reviews contributed by scientists who are leading specialists in their field of expertise. Authors wishing to contribute a review paper are advised first to contact the Editor in Chief.

Short Communications:

Technical reports: Technical reports should present brief descriptions of novel apparatus, a new experimental or computational method, test or procedure, or an improvement or noteworthy modification of an already existing technique or platform used in the proteomic workflow. Technical reports should show a realistic application of the methodology described. Theoretical papers dealing with mechanistic aspects of proteomic techniques will also be considered. A technical report should be a short (no more than two pages when published) description written in a continuous style with no more than two figures and one table.

Data reports:

News & Views: News & Views point out the author(s) vision of the character and importance of a new direction in proteome research. They are not intended to be accounts or analyses of an individual's personal research. Although News & Views will usually be invited, they can be submitted without invitation. Author(s) are encouraged to suggest experts in the field who can act as reviewers.

Letters to the Editor: Letters to the Editor are intended to stimulate discussion and debate in areas of general concern and controversy in proteomics, and generally reflect the personal opinions of the author(s). They should be written in a continuous style and should normally not exceed two printed pages and contain no more than one figure or table.

Page charges

This title is fully open access and therefore funded not through library subscription payments but through author fees. If you would like your article to be published open access, but you genuinely cannot afford these fees, then individual waiver requests are considered on a case-by-case basis and may be granted in cases of genuine need. Priority for this waiver programme will be given to applications by authors from countries eligible for the Research4Life programme. See http://www.research4life.org/institutions.html. Note that in 2013 all charges will be waived as an introductory offer.

Ethics in publishing

For information on Ethics in publishing and Ethical guidelines for journal publication see http://www.elsevier.com/publishingethics and http://www.elsevier.com/ethicalguidelines.

Policy and ethics

The work described in your article must have been carried out in accordance with The Code of Ethics of the World Medical Association (Declaration of Helsinki) for experiments involving humans http://www.wma.net/en/30publications/10policies/b3/index.html; EU Directive 2010/63/EU for animal experiments http://ec.europa.eu/environment/chemicals/lab_animals/legislation_en.htm; Uniform Requirements for manuscripts submitted to Biomedical journals http://www.icmje.org. This must be stated at an appropriate point in the article.

Animal experiments
Where animals have been used in a study, the institutional ethical or animal welfare authority under which the work was conducted must be stated, along with the specific authorisation reference number. Circumstances relating to animal experimentation must meet the International Guiding Principles for Biomedical Research Involving Animals, as issued by the Council for the International Organizations of Medical Sciences. These guidelines are obtainable from: Executive Secretary C.I.O.M.S., c/o WHO, Appia, CH-1211 Geneva 27, Switzerland, or at the following URL: http://www.cioms.ch/frame_1985_texts_of_guidelines.htm.

EuPA Open Proteomics will reject any paper where there is reason to believe that animals have been subjected to unnecessary or avoidable pain or distress.

Conflict of interest

All authors are requested to disclose any actual or potential conflict of interest including any financial, personal or other relationships with other people or organizations within three years of beginning the submitted work that could inappropriately influence, or be perceived to influence, their work. See also http://www.elsevier.com/conflictsofinterest. Further information and an example of a Conflict of Interest form can be found at: http://elsevier6.custhelp.com/app/answers/detail/a_id/286/p/7923/.

Submission declaration

Submission of an article implies that the work described has not been published previously (except in the form of an abstract or as part of a published lecture or academic thesis or as an electronic preprint, see http://www.elsevier.com/postingpolicy), that it is not under consideration for publication elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere including electronically in the same form, in English or in any other language, without the written consent of the copyright-holder.

Authorship
All authors should have made substantial contributions to all of the following: (1) the conception and design of the study, or acquisition of data, or analysis and interpretation of data, (2) drafting the article or revising it critically for important intellectual content, (3) final approval of the version to be submitted.

Changes to authorship

This policy concerns the addition, deletion, or rearrangement of author names in the authorship of accepted manuscripts:
Before the accepted manuscript is published in an online issue: Requests to add or remove an author, or to rearrange the author names, must be sent to the Journal Manager from the corresponding author of the accepted manuscript and must include: (a) the reason the name should be added or removed, or the author names rearranged and (b) written confirmation (e-mail, fax, letter) from all authors that they agree with the addition, removal or rearrangement. In the case of addition or removal of authors, this includes confirmation from the author being added or removed. Requests that are not sent by the corresponding author will be forwarded by the Journal Manager to the corresponding author, who must follow the procedure as described above. Note that: (1) Journal Managers will inform the Journal Editors of any such requests and (2) publication of the accepted manuscript in an online issue is suspended until authorship has been agreed.
After the accepted manuscript is published in an online issue: Any requests to add, delete, or rearrange author names in an article published in an online issue will follow the same policies as noted above and result in a corrigendum.

Copyright

Authors will be asked to sign an exclusive publishing agreement that allows them to retain copyright of their work. Authors can choose to publish their work under one of two Creative Common licenses. The first option is the Creative Commons Attribution 3.0 Unported License (or CC BY), which allows users to alter and build upon the article and then distribute the resulting work, even commercially. As with all Creative Commons licenses the work must be attributed to the original author and publisher. This license encourages maximum use and redistribution. The full details of the license are available at http://creativecommons.org/licenses/by/3.0/legalcode. The second option is the Creative Commons Attribution-Noncommercial-ShareAlike Works 3.0 Unported License (or CC BY-NC-SA), which permits non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited. The full details of the license are available at http://creativecommons.org/licenses/by-nc-sa/3.0/legalcode. To provide open access, expenses are offset by a publication fee of 1,700 EUR that will allow EuPA Open Proteomics to support itself in a fully sustainable way. Students from affiliated societies receive a discount.

Retained author rights

Authors retain the copyright of their work.

Role of the funding source

You are requested to identify who provided financial support for the conduct of the research and/or preparation of the article and to briefly describe the role of the sponsor(s), if any, in study design; in the collection, analysis and interpretation of data; in the writing of the report; and in the decision to submit the article for publication. If the funding source(s) had no such involvement then this should be stated. Please see http://www.elsevier.com/funding.

Funding body agreements and policies

Elsevier has established agreements and developed policies to allow authors whose articles appear in journals published by Elsevier, to comply with potential manuscript archiving requirements as specified as conditions of their grant awards. To learn more about existing agreements and policies please visit http://www.elsevier.com/fundingbodies.

Open access

EuPA Open Proteomics follows an author-pays open access model. The charge for publication is 1,700 EUR. Students from affiliated societies receive a discount. This charge is necessary to offset publishing costs - from managing article submission to typesetting, tagging and indexing of articles, hosting articles on dedicated servers, supporting sales and marketing costs to ensure global dissemination via ScienceDirect, and permanently preserving the journal article. The fee excludes any appropriate taxes. Payment is required before the article will be released for publication. Note that in 2013 all charges will be waived as an introductory offer.

Language (usage and editing services)

Please write your text in good English (American or British usage is accepted, but not a mixture of these). Authors who feel their English language manuscript may require editing to eliminate possible grammatical or spelling errors and to conform to correct scientific English may wish to use the English Language Editing service available from Elsevier's WebShop http://webshop.elsevier.com/languageediting/ or visit our customer support site http://support.elsevier.com for more information.

Submission

Submission to this journal proceeds totally online and you will be guided stepwise through the creation and uploading of your files. The system automatically converts source files to a single PDF file of the article, which is used in the peer-review process. Please note that even though manuscript source files are converted to PDF files at submission for the review process, these source files are needed for further processing after acceptance. All correspondence, including notification of the Editor's decision and requests for revision, takes place by e-mail removing the need for a paper trail.

Submit your article

Please submit your article via http://ees.elsevier.com/euprot.

Referees

Please provide the names and addresses of 4 - 5 suitable potential reviewers. If there are compelling reasons for excluding some individuals as potential reviewers, these can be mentioned. However, choice of reviewers is at the Editors' discretion.

Use of wordprocessing software

It is important that the file be saved in the native format of the wordprocessor used. The text should be in single-column format. Keep the layout of the text as simple as possible. Most formatting codes will be removed and replaced on processing the article. In particular, do not use the wordprocessor's options to justify text or to hyphenate words. However, do use bold face, italics, subscripts, superscripts etc. When preparing tables, if you are using a table grid, use only one grid for each individual table and not a grid for each row. If no grid is used, use tabs, not spaces, to align columns. The electronic text should be prepared in a way very similar to that of conventional manuscripts (see also the Guide to Publishing with Elsevier: http://www.elsevier.com/guidepublication). Note that source files of figures, tables and text graphics will be required whether or not you embed your figures in the text. See also the section on Electronic artwork.
To avoid unnecessary errors you are strongly advised to use the 'spell-check' and 'grammar-check' functions of your wordprocessor.

To assist in the reviewing of your paper, please add line numbering to your manuscript file.

Article structure

Original articles are usually divided into the sections Introduction, Materials and methods, Results, Discussion and Conclusions:

Introduction
This is a short section in which the authors should state the reasons for performing the work, with brief reference to relevant previous work.

Material and methods
Provide sufficient detail to allow the work to be reproduced. Methods already published should be indicated by a reference: only relevant modifications should be described.

Results
Results should be clear and concise.

Discussion
This should explore the significance of the results of the work, not repeat them. A combined Results and Discussion section is often appropriate. Avoid extensive citations and discussion of published literature.

Conclusions
The main conclusions of the study may be presented in a short Conclusions section, which may stand alone or form a subsection of a Discussion or Results and Discussion section.

Technical reports, News & Views, Letters to the Editor
These types of papers are not divided into sections after the summary, except for the reference list. The first paragraph serves as an introduction; acknowledgments are added as a final paragraph before the reference list.

Essential title page information

• Title. Concise and informative. Titles are often used in information-retrieval systems. Avoid abbreviations and formulae where possible.
• Author names and affiliations. Where the family name may be ambiguous (e.g., a double name), please indicate this clearly. Present the authors' affiliation addresses (where the actual work was done) below the names. Indicate all affiliations with a lower-case superscript letter immediately after the author's name and in front of the appropriate address. Provide the full postal address of each affiliation, including the country name and, if available, the e-mail address of each author.
• Corresponding author. Clearly indicate who will handle correspondence at all stages of refereeing and publication, also post-publication. Ensure that phone numbers (with country and area code) are provided in addition to the e-mail address and the complete postal address. Contact details must be kept up to date by the corresponding author.
• Present/permanent address. If an author has moved since the work described in the article was done, or was visiting at the time, a 'Present address' (or 'Permanent address') may be indicated as a footnote to that author's name. The address at which the author actually did the work must be retained as the main, affiliation address. Superscript Arabic numerals are used for such footnotes.

Abstract

A concise and factual abstract is required. The abstract should state briefly the purpose of the research, the principal results and major conclusions. An abstract is often presented separately from the article, so it must be able to stand alone. For this reason, References should be avoided, but if essential, then cite the author(s) and year(s). Also, non-standard or uncommon abbreviations should be avoided, but if essential they must be defined at their first mention in the abstract itself.

Graphical abstract

A Graphical abstract is mandatory for this journal. It should summarize the contents of the article in a concise, pictorial form designed to capture the attention of a wide readership online. Authors must provide images that clearly represent the work described in the article. Graphical abstracts should be submitted as a separate file in the online submission system. Image size: please provide an image with a minimum of 531 × 1328 pixels (h × w) or proportionally more. The image should be readable at a size of 5 × 13 cm using a regular screen resolution of 96 dpi. Preferred file types: TIFF, EPS, PDF or MS Office files. See http://www.elsevier.com/graphicalabstracts for examples.
Authors can make use of Elsevier's Illustration and Enhancement service to ensure the best presentation of their images also in accordance with all technical requirements: Illustration Service.

Graphical Abstract should allow readers to quickly gain an understanding of the main take-home message of the paper and is intended to encourage browsing, promote interdisciplinary scholarship, and help readers identify more quickly which papers are most relevant to their research interests. The Graphical Abstract should summarize the contents of the paper in a concise, pictorial form designed to capture the attention of a wide readership. Authors must provide images that clearly represent the work described in the paper. A key, summarising figure taken from the original paper can also be submitted as a graphical abstract.

Graphical Abstracts should be submitted as a separate file in EES by selecting "Graphical Abstract" from the drop-down box when uploading files.

Highlights

Highlights are mandatory for this journal. They consist of a short collection of bullet points that convey the core findings of the article and should be submitted in a separate file in the online submission system. Please use 'Highlights' in the file name and include 3 to 5 bullet points (maximum 85 characters, including spaces, per bullet point). See http://www.elsevier.com/highlights for examples.

Database linking

Elsevier encourages authors to connect articles with external databases, giving their readers one-click access to relevant databases that help to build a better understanding of the described research. Please refer to relevant database identifiers using the following format in your article: Database: xxxx (e.g., TAIR: AT1G01020; CCDC: 734053; PDB: 1XFN). See http://www.elsevier.com/databaselinking for more information and a full list of supported databases.

Artwork

Electronic artwork
General points

• Make sure you use uniform lettering and sizing of your original artwork
• Save text in illustrations as "graphics" or enclose the font
• Only use the following fonts in your illustrations: Arial, Courier, Times, Symbol
• Number the illustrations according to their sequence in the text
• Use a logical naming convention for your artwork files
• Provide captions to illustrations separately
• Produce images near to the desired size of the printed versio
• Submit each figure as a separate file.

A detailed guide on electronic artwork is available on our website: http://www.elsevier.com/artworkinstructions You are urged to visit this site; some excerpts from the detailed information are given here.

Formats

Regardless of the application used, when your electronic artwork is finalised, please "save as" or convert the images to one of the following formats (note the resolution requirements for line drawings, halftones, and line/halftone combinations given below):

EPS: Vector drawings. Embed the font or save the text as "graphics".
TIFF: color or grayscale photographs (halftones): always use a minimum of 300 dpi.
TIFF: Bitmapped line drawings: use a minimum of 1000 dpi.
TIFF: Combinations bitmapped line/half-tone (color or grayscale): a minimum of 500 dpi is required.
DOC, XLS or PPT: If your electronic artwork is created in any of these Microsoft Office applications please supply "as is".
Please do not:

• Supply embedded graphics in your wordprocessor (spreadsheet, presentation) document;
• Supply files that are optimised for screen use (like GIF, BMP, PICT, WPG); the resolution is too low;
• Supply files that are too low in resolution;
• Submit graphics that are disproportionately large for the content.

Figure captions
Ensure that each illustration has a caption. Supply captions separately, not attached to the figure. A caption should comprise a brief title (not on the figure itself) and a description of the illustration. Keep text in the illustrations themselves to a minimum but explain all symbols and abbreviations used.

Tables

Number tables consecutively in accordance with their appearance in the text. Place footnotes to tables below the table body and indicate them with superscript lowercase letters. Avoid vertical rules. Be sparing in the use of tables and ensure that the data presented in tables do not duplicate results described elsewhere in the article.

References

Citation in text
The numerical system of references should be used. References in the text should be cited by numbers in square brackets in the order of their citation.

References are listed together in their order of appearance in a separate section at the end of the text under the heading References. All references should be numbered consecutively. References to journals should contain initials and names of all authors, article title, abbreviation of the name of the journal according to the List of Serial Title World Abbreviations (International Series Data System, 20, rue Bachaumont, 75002 Paris, France. ISBN 2-904938-02-8), year of publication, volume number, and page numbers. References to books should also include the title (of series and volumes), initials and names of the editor(s), the publisher and place of publication.

Examples:

Reference to a journal publication:

[1] Resing KA, Ahn NG. Proteomics strategies for protein identification. FEBS Letters 2005;579:885-9.

Reference to a book:

[2] Rehm H. Protein Biochemistry and Proteomics. San Diego: Academic Press/Elsevier Inc; 2006.

Reference to a chapter in an edited book or book series:

[3] Morgan JW, Hettick JM, Russell DH. Peptide sequencing by MALDI 193-nm photodissociation TOF MS. In: Burlingame AL, editor. Methods in Enzymology, vol 402: Biological Mass Spectrometry. San Diego: Academic Press/Elsevier Inc; 2005, p.186-209.

Reference to a paper as "in press" implies that it has been accepted for publication. Evidence (e.g., a photocopy of the note of acceptance from the journal concerned) should accompany the submitted typescript. Papers that are "in press" should be included as a number in the text. Other papers submitted before or simultaneously with the paper in question should be included as a number in the text and in the References section, stating the name of the journal. Copies of papers that are submitted elsewhere should be provided for inspection by the Editors. Omission of this information will delay publication and may lead to redating of a submitted manuscript. Papers presented at scientific meetings that are not available in published form should not be cited as references in the References section.

Unpublished results should not be listed in the References section. In the text they are mentioned as follows: "(Tervoort MV and Glimcher J, unpublished data)". When unpublished results are cited, the data should be provided for the Editors' information when essential for proper evaluation, or if requested.

A personal communication should be mentioned in the text as follows: "(Tervoort MV, personal communication)". Authors should not make unauthorized use of personal communications. Personal communications are not to be included in the Reference section.

Reference management software
This journal has standard templates available in key reference management packages EndNote (http://www.endnote.com/support/enstyles.asp) and Reference Manager (http://refman.com/support/rmstyles.asp). Using plug-ins to wordprocessing packages, authors only need to select the appropriate journal template when preparing their article and the list of references and citations to these will be formatted according to the journal style which is described below.

Reference style
Text: Indicate references by number(s) in square brackets in line with the text. The actual authors can be referred to, but the reference number(s) must always be given.
Example: '..... as demonstrated [3,6]. Barnaby and Jones [8] obtained a different result ....'
List: Number the references (numbers in square brackets) in the list in the order in which they appear in the text.
Examples:
Reference to a journal publication:
[1] J. van der Geer, J.A.J. Hanraads, R.A. Lupton, The art of writing a scientific article, J. Sci. Commun. 163 (2010) 51–59.
Reference to a book:
[2] W. Strunk Jr., E.B. White, The Elements of Style, fourth ed., Longman, New York, 2000.
Reference to a chapter in an edited book:
[3] G.R. Mettam, L.B. Adams, How to prepare an electronic version of your article, in: B.S. Jones, R.Z. Smith (Eds.), Introduction to the Electronic Age, E-Publishing Inc., New York, 2009, pp. 281–304.

Video data

Elsevier accepts video material and animation sequences to support and enhance your scientific research. Authors who have video or animation files that they wish to submit with their article are strongly encouraged to include links to these within the body of the article. This can be done in the same way as a figure or table by referring to the video or animation content and noting in the body text where it should be placed. All submitted files should be properly labeled so that they directly relate to the video file's content. In order to ensure that your video or animation material is directly usable, please provide the files in one of our recommended file formats with a preferred maximum size of 50 MB. Video and animation files supplied will be published online in the electronic version of your article in Elsevier Web products, including ScienceDirect: http://www.sciencedirect.com. Please supply 'stills' with your files: you can choose any frame from the video or animation or make a separate image. These will be used instead of standard icons and will personalize the link to your video data. For more detailed instructions please visit our video instruction pages at http://www.elsevier.com/artworkinstructions. Note: since video and animation cannot be embedded in the print version of the journal, please provide text for both the electronic and the print version for the portions of the article that refer to this content.

Supplementary data

Elsevier accepts electronic supplementary material to support and enhance your scientific research. Supplementary files offer the author additional possibilities to publish supporting applications, high-resolution images, background datasets, sound clips and more. Supplementary files supplied will be published online alongside the electronic version of your article in Elsevier Web products, including ScienceDirect: http://www.sciencedirect.com. In order to ensure that your submitted material is directly usable, please provide the data in one of our recommended file formats. Authors should submit the material in electronic format together with the article and supply a concise and descriptive caption for each file. For more detailed instructions please visit our artwork instruction pages at http://www.elsevier.com/artworkinstructions.

Submission checklist

The following list will be useful during the final checking of an article prior to sending it to the journal for review. Please consult this Guide for Authors for further details of any item.
Ensure that the following items are present:
One author has been designated as the corresponding author with contact details:
• E-mail address
• Full postal address
• Telephone number

All necessary files have been uploaded, and contain:
• Keywords
•Graphical abstract
• Highlights
• STARD, REMARKS and/or CONSORT checklists
• Mass spectrometry checklist
• Minimum information for biological and biomedical investigation checklists
• All figure captions
• All tables (including title, description, footnotes)

Further considerations
• Manuscript has been 'spell-checked' and 'grammar-checked'
• References are in the correct format for this journal
• All references mentioned in the Reference list are cited in the text, and vice versa
• Permission has been obtained for use of copyrighted material from other sources (including the Web)
• Line numbers have been added to your manuscript file.

Use of the Digital Object Identifier

The Digital Object Identifier (DOI) may be used to cite and link to electronic documents. The DOI consists of a unique alpha-numeric character string which is assigned to a document by the publisher upon the initial electronic publication. The assigned DOI never changes. Therefore, it is an ideal medium for citing a document, particularly 'Articles in press' because they have not yet received their full bibliographic information. Example of a correctly given DOI (in URL format; here an article in the journal Physics Letters B):
http://dx.doi.org/10.1016/j.physletb.2010.09.059
When you use a DOI to create links to documents on the web, the DOIs are guaranteed never to change.

Offprints

The corresponding author, at no cost, will be provided with a PDF file of the article via e-mail. The PDF file is a watermarked version of the published article and includes a cover sheet with the journal cover image and a disclaimer outlining the terms and conditions of use.

Additional information

Appendix

Standard abbreviations allowed to be used without explanation or definition in all articles published in EuPA Open Proteomics.

A absorbance

ACES 2-[(2-amino-2-oxoethyl)amino] ethanesulphonic acid

CAN acetonitrile

A/D analog to digital converter

AEBSF 4-(2-aminoethyl)benzenesulphonyl fluoride

amu atomic mass unit

ANOVA analysis of variance

API atmospheric pressure ionization

AUC area under curve

Bis N,N'-methylenebisacrylamide

bp base pairs

BSA bovine serum albumin

%C cross-linking agent (g/100 mL)/%T

CAPS 3-(cyclohexylamino)-1-propanesulphonic acid

CBB Coomassie Brilliant Blue

CCD charge-coupled device

CD circular dicroism

CE capillary electrophoresis

CEC capillary electrochromatography

CFE continuous flow electrophoresis

CHAPS 3-[(3-cholamidopropyl)dimethylamonio]-1-propanesulphonate

CHCA ?-cyano-4-hydroxycinnamic acid

CHES 2-(N-cyclohexylamino)ethanesulphonic acid

CID collision-induced dissociation

CIEF capillary isoelectric focusing

CMC critical micelle concentration

Con A Concanavalin A

CNS central nervous system

cpm counts per minute

CTAB etyltrimethylammonium bromide

CV coefficient of variation

CZE capillary zone electrophoresis

1-D one-dimensional

2-D two-dimensional

Da dalton (molecular mass)

2-DE two-dimensional electrophoresis

DIGE fluorescence difference gel electrophoresis

DGGE denaturing gradient gel electrophoresis

DMEM Dulbecco's modified Eagle medium

DMF N,N-dimethylformamide

DMSO dimethyl sulphoxide

DOC sodium deoxycholate

dsDNA double-stranded DNA

DTE dithioerithriol

DTT dithiothreitol

ECL enhanced chemiluminescence

EDTA ethylenediaminetetraacetic acid

EEO electroendosmosis

EGTA ethylene glycol-bis(?-aminoethylether)-N,N,N',N'-tetraacetic acid

EKC electrokinetic chromatography

ELISA enzyme-linked immunosorbent assay

EMSA electrophoretic mobility shift assay

EOF electroosmotic flow

ER endoplasmic reticulum

ESI electrospray ionization

EST expressed sequence tag

EUPA European Proteome Association

FAB fast atom bombardment

FACS fluorescence activated cell sorting

FBS fetal bovine serum

FCS fetal calf serum

FIGE field inversion gel electrophoresis

FITC fluorescein isothiocyanate

FT Fourier transform

FT-ICR Fourier transform-ion cyclotron resonance

GC gas chromatography

GIF graphic interchange format

GRAVY grand average hydrophobicity

GSH glutathione

GST glutathione-S-transferase

HE hematoxylin and eosin

HEPES N-(2-hydroxyethyl)piperazine-2'-(2-ethanesulphonic acid)

HPCE high-performance capillary electrophoresis

HPLC high-performance liquid chromatography

HRP horseradish peroxidase

HSA human serum albumin

HSP heat shock protein

HTML hypertext mark-up language

HUPO Human Proteome Organisation

HVR hypervariable region

ICAT isotop-coded affinity tag

ICR ion cyclotron resonance

id inside diameter

IEF isoelectric focusing

Ig immunoglobulin

IMAC immobilized metal affinity capture

IPG immobilized pH gradient

IT ion trap

iTRAQ isobaric tag for relative and absolute quantitation

kbp kilobase pairs

kDa kilodalton (molecular mass)

LC liquid chromatography

LED light-emitting diode

LOD limit of detection

LOQ limit of quantitation

mAb monoclonal antibody

MALDI-MS matrix-assisted laser-desorption ionization-mass spectrometry

Mbp megabase

MEKC micellar electrokinetic capillary chromatography

MES 2-(N-morpholino)ethanesulphonic acid

MHC major histocompatibility complex

MOPS 3-(N-morpholino)propanesulphonic acid

Mr relative molecular mass (dimensionless)

MS mass spectrometry

MS/MS tandem mass spectromet

For inquiries relating to the submission of articles (including electronic submission) please visit this journal's homepage. For detailed instructions on the preparation of electronic artwork, please visit http://www.elsevier.com/artworkinstructions. Contact details for questions arising after acceptance of an article, especially those relating to proofs, will be provided by the publisher. You can track accepted articles at http://www.elsevier.com/trackarticle. You can also check our Author FAQs at http://www.elsevier.com/authorFAQ and/or contact Customer Support via http://support.elsevier.com.