Guide for Authors

  • All journal information and instructions compiled in one document (PDF) in just one mouse-click Author information pack

    BEFORE YOU BEGIN
    • Ethics in Publishing
    • Conflict of Interest
    • Submission declaration
    • Clinical Trials
    • Copyright
    • Role of the funding source
    • Funding body agreements and policies
    • OA Options
    • Open access
    • Language (usage and editing services)
    • Submission
    • Referees
    PREPARATION
    • Use of word processing software
    • Article structure
    • Graphical abstract
    • Highlights
    • Nomenclature and units
    • Math formulae
    • Artwork
    • Tables
    • References
    • Video data
    • AudioSlides
    • Supplementary data
    • Submission checklist
    • Additional Information
    AFTER ACCEPTANCE
    • Use of the Digital Object Identifier
    • Proofs
    • Offprints
    AUTHOR INQUIRIES


    Cytotherapy publishes original articles, reviews, commentaries, letteres to the editor, short reports, and editorials. All submitted manuscripts will be reviewed by at least two reviewers.

    Aims and Scope Cytotherapy publishes cutting edge findings, clinical trials of cell-based therapies, and news and opinion on all aspects of the rapidly expanding field of cell-based treatments for cancer, degenerative disorders, immunotherapy and stem cell transplantation. The journal focuses especially on the practical translation of scientific developments in the laboratory into clinical practice. Cytotherapy is an essential global resource for clinical researchers, oncologists, hematologists, physicians, and regulatory experts involved in cell processing and therapy. The journal’s scope covers: Stem cell processing and transplantation; cell-based therapies of malignant and non-malignant blood diseases; cancer; stem cell plasticity; autoimmune diseases; immunotherapy; congenital disorders; novel molecular therapies; gene therapy; microvesicle biology and therapeutic application.

    Original Articles: should not exceed 6000 words excluding references (usually less than 50). Typically we allow up to 8 figures and 6 tables. Consider including more data as supplementary figures.

    Short Reports: should not exceed 3000 words excluding references; they may contain up to 3 figures or tables.

    Reviews: Review articles are usually solicited. However, Cytotherapy occasionally publishes unsolicited reviews. Reviews should not exceed 12,000 words excluding references (typically less than 150). They may include up to 6 figures and tables. Mini reviews (less than 5000 words) are accepted.

    Commentaries and Letters to the Editor: are formatted in a series of paragraphs with up to 10 references. Typical length is 300-1000 words. No abstract is required. Letters may include a single figure or table.Letters to the editor: The journal welcomes correspondence. Letters may be submitted as free text. Accompanying references, figures and tables should be submitted using the format for original papers.

    In Focus issues: In Focus editions will contain a guest editorial, reviews and original papers following the guidelines above.

    ISCT Committee Reports A brief introductory paragraph <200 words serving as a summary of the article. The article should be up to 3000 words (max.), arranged in paragraphs (subheadings as appropriate) and a conclusion paragraph; it may include up to three tables/figures and 20 references if needed. Up to 3 Authors of the report, all other members of the committee to be listed as a footnote. Subject to peer review and editorial modifications for style and presentation.

    Other formats: The journal will accept free-text submissions describing meeting reports, regulatory guidelines, classification systems, standard operating procedures and miscellaneous reports. These will be published as "Meeting Reports" or "Letters to the Editor".

    Manuscripts should be submitted online: http://mc.manuscriptcentral.com/cytotherapy. New users should start by creating an account and then follow the instructions provided. Manuscripts are submitted through the Author Centre. Authors for invited articles should follow the instructions given in the invitation e-mail.

    Ethics in Publishing

    Cytotherapy considers research and publication misconduct to be a serious breach of ethics, and will take such actions as necessary to address such misconduct. Authors should refer to the Committee on Publication Ethics (COPE) and the International Committee of Medical Journal Editors for full information. Authors are also encouraged to visit Elsevier's Ethical Guidelines for Journal Publication. Plagiarism and duplicate submission are serious acts of misconduct. Plagiarism is defined as unreferenced use of published or unauthorized use of unpublished ideas, and may occur at any stage of planning, researching, writing, or publication. Plagiarism takes many forms, from 'passing off' another's paper as the author's own paper, to copying or paraphrasing substantial parts of another's paper (without attribution), to claiming results from research conducted by others. Plagiarism in all its forms constitutes unethical publishing behavior and is unacceptable. Duplicate submission/publication occurs when two or more papers, without full cross-reference, share the same hypothesis, data, discussion points, or conclusions. Identifying information should not be published in written declarations, photographs or pedigrees. Do not reveal patients' names, initials or hospital numbers, for example in illustrative material. Photographs of human subjects must be accompanied by informed consent of the person(s) concerned and requires that the person should see the manuscript before publication. Facial features must be unrecognizable. The Editorial Office may request the authors to supply a PDF copy (or paper copy) of an ethical committee approval for articles describing animal experiments or clinical studies/trials (patients, patient material, medical records), including a verified and official translation of such documents. State in the ethics section that the procedures of the study received ethics approval from the relevant and named national, regional or institutional ethics/review committee(s) responsible for human/animal experimentation. Supply the date of issue and registration number. If no ethics approval was received, explain why, including an explanation as to how the study adhered to the Helsinki Declaration. If deemed necessary by the Editors, cases will be submitted to COPE (Committee on Publication Ethics).

    Permissions
    Permission to reproduce material published in other journals must be sought by the authors before publication of the article. A note about permissions granted should be included in the cover letter submitted together with the manuscript. More information can be found at http://www.elsevier.com/wps/find/authorsview.authors/non-elsevier_permissions. Permission to republish material from Cytotherapy can be sought directly online. Look for the article on the journal website and use the "Rights/Permissions" or "Permissions & Reprints" link. For more information please visit: http://www.elsevier.com/wps/find/authorsview.authors/permissionsguide.

    Conflict of Interest

    Authors are responsible for recognizing and disclosing any conflict of interest, or potential conflict of interest, that may bias their work, or could be perceived to bias their work, and acknowledge all financial support and any other personal connections. Cytotherapy adheres to the ICMJE guidelines, including those on Conflict of Interest and Authorship. Please indicate any activities that apply to the past five years and foreseeable future. Authors must complete the Journal's Conflict of Interest form and upload it with their manuscript and figure files during the electronic submission process. See also http://www.elsevier.com/conflictsofinterest.

    Submission declaration

    Submission of an article implies that the work described has not been published previously (except in the form of an abstract or as part of a published lecture or academic thesis or as an electronic preprint, see http://www.elsevier.com/postingpolicy), that it is not under consideration for publication elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere including electronically in the same form, in English or in any other language, without the written consent of the copyright-holder.

    Clinical Trials

    Cytotherapy will not publish clinical trial data unless the manuscript indicates that approval by a local ethical committee, and informed consent has been obtained according to the Helsinki Declaration.

    Copyright

    This journal offers authors a choice in publishing their research: Open access and Subscription.

    For subscription articles
    Upon acceptance of an article, authors will be asked to complete a 'Journal Publishing Agreement' (for more information on this and copyright, see http://www.elsevier.com/copyright). An e-mail will be sent to the corresponding author confirming receipt of the manuscript together with a 'Journal Publishing Agreement' form or a link to the online version of this agreement.
    Subscribers may reproduce tables of contents or prepare lists of articles including abstracts for internal circulation within their institutions. Permission of the Publisher is required for resale or distribution outside the institution and for all other derivative works, including compilations and translations (please consult http://www.elsevier.com/permissions). If excerpts from other copyrighted works are included, the author(s) must obtain written permission from the copyright owners and credit the source(s) in the article. Elsevier has preprinted forms for use by authors in these cases: please consult http://www.elsevier.com/permissions.

    For open access articles
    Upon acceptance of an article, authors will be asked to complete an 'Exclusive License Agreement' (for more information see http://www.elsevier.com/OAauthoragreement). Permitted reuse of open access articles is determined by the author's choice of user license (see http://www.elsevier.com/openaccesslicenses).

    Retained author rights
    As an author you (or your employer or institution) retain certain rights. For more information on author rights for:
    Subscription articles please see http://www.elsevier.com/journal-authors/author-rights-and-responsibilities.
    Open access articles please see http://www.elsevier.com/OAauthoragreement.

    Role of the funding source

    You are requested to identify who provided financial support for the conduct of the research and/or preparation of the article and to briefly describe the role of the sponsor(s), if any, in study design; in the collection, analysis and interpretation of data; in the writing of the report; and in the decision to submit the article for publication. If the funding source(s) had no such involvement then this should be stated.

    Funding body agreements and policies

    Elsevier has established agreements and developed policies to allow authors whose articles appear in journals published by Elsevier, to comply with potential manuscript archiving requirements as specified as conditions of their grant awards. To learn more about existing agreements and policies please visit http://www.elsevier.com/fundingbodies.

    OA Options

    This journal does not ordinarily have publication charges; however, authors can now opt to make their articles available to all (including non-subscribers) via the ScienceDirect platform, for which a standard fee of $3,000 USD for non ISCT members and $2,700 USD for ISCT members applies (for further information on open access see http://www.elsevier.com/about/open-access/open-access-options). Please note that you can only make this choice after receiving notification that your article has been accepted for publication, to avoid any perception of conflict of interest. The fee excludes taxes and other potential costs such as color charges. In some cases, institutions and funding bodies have entered into agreement with Elsevier to meet these fees on behalf of their authors. Details of these agreements are available at http://www.elsevier.com/fundingbodies. Authors of accepted articles, who wish to take advantage of this option, should complete and submit the order form (available at http://www.elsevier.com/locate/openaccessform.pdf). Whatever access option you choose, you retain many rights as an author, including the right to post a revised personal version of your article on your own website. More information can be found here: http://www.elsevier.com/authorsrights.
    Your publication choice will have no effect on the peer review process or acceptance of submitted articles.

    Open access

    This journal offers authors a choice in publishing their research:

    Open Access
    • Articles are freely available to both subscribers and the wider public with permitted reuse
    • An Open Access publication fee is payable by authors or their research funder
    Subscription
    • Articles are made available to subscribers as well as developing countries and patient groups through our access programs (http://www.elsevier.com/access)
    • No Open Access publication fee

    All articles published Open Access will be immediately and permanently free for everyone to read and download. Permitted reuse is defined by the following Creative Commons user license:
    Creative Commons Attribution-NonCommercial-NoDerivs (CC BY-NC-ND): for non-commercial purposes, lets others distribute and copy the article, and to include in a collective work (such as an anthology), as long as they credit the author(s) and provided they do not alter or modify the article.

    Elsevier has established agreements with funding bodies, http://www.elsevier.com/fundingbodies. This ensures authors can comply with funding body Open Access requirements, including specific user licenses, such as CC BY. Some authors may also be reimbursed for associated publication fees. If you need to comply with your funding body policy, you can apply for the CC BY license after your manuscript is accepted for publication.

    To provide Open Access, this journal has a publication fee which needs to be met by the authors or their research funders for each article published Open Access.
    Your publication choice will have no effect on the peer review process or acceptance of submitted articles.

    The open access publication fee for this journal is $3,000, excluding taxes. Learn more about Elsevier's pricing policy: http://www.elsevier.com/openaccesspricing.

    Language (usage and editing services)

    Please write your text in good English (American or British usage is accepted, but not a mixture of these). Authors who feel their English language manuscript may require editing to eliminate possible grammatical or spelling errors and to conform to correct scientific English may wish to use the English Language Editing service available from Elsevier's WebShop (http://webshop.elsevier.com/languageediting/) or visit our customer support site (http://support.elsevier.com) for more information.

    Language
    Either English or American spelling is accepted if used consistently throughout the manuscript. Authors who are not fluent in English should use the help of a colleague or translator who is proficient in medical English before submitting the manuscript for consideration. The quality of the language is the author's responsibility. All manuscripts will undergo copyediting before printing, but significant language editing will not be undertaken. Poor quality of English masks the possible scientific merit of some papers, and can delay publication or lead to outright rejection of the paper. More on language editing and quality may be found at http://www.elsevier.com/wps/find/authorsview.authors/languageediting/, and information on language editing services can be found at http://webshop.elsevier.com/languageediting/.

    Submission

    Submission to this journal proceeds totally online and you will be guided stepwise through the creation and uploading of your files. The system automatically converts source files to a single PDF file of the article, which is used in the peer-review process. Please note that even though manuscript source files are converted to PDF files at submission for the review process, these source files are needed for further processing after acceptance. All correspondence, including notification of the Editor's decision and requests for revision, takes place by e-mail removing the need for a paper trail.

    Referees

    Please submit the names and institutional e-mail addresses of several potential referees. For more details, visit our Support site. Note that the editor retains the sole right to decide whether or not the suggested reviewers are used.

    Additional Information
    A Cover Letter should be provided, where authors vouch for the accuracy of the manuscript according to the guidelines given here. This is also the place where authors may inform the editors of any special circumstances or details regarding the submitted material, including prior publication of the material/parts of the material in a minority language. Authors are welcome to recommend reviewers in the cover letter, particularly if they are Cytotherapy editorial board members. Associate Editors should not be recommended as reviewers.

    Use of word processing software

    It is important that the file be saved in the native format of the word processor used. The text should be in single-column format. Keep the layout of the text as simple as possible. Most formatting codes will be removed and replaced on processing the article. In particular, do not use the word processor's options to justify text or to hyphenate words. However, do use bold face, italics, subscripts, superscripts etc. When preparing tables, if you are using a table grid, use only one grid for each individual table and not a grid for each row. If no grid is used, use tabs, not spaces, to align columns. The electronic text should be prepared in a way very similar to that of conventional manuscripts (see also the Guide to Publishing with Elsevier: http://www.elsevier.com/guidepublication). Note that source files of figures, tables and text graphics will be required whether or not you embed your figures in the text. See also the section on Electronic artwork.
    To avoid unnecessary errors you are strongly advised to use the 'spell-check' and 'grammar-check' functions of your word processor.

    Article structure

    Manuscript files should be structured as follows: (1) Title page; (2) Abstract; (3) Keywords; (4) Abbreviations; (5) Main text; (6) Acknowledgments; (7) Disclosure of Interest; (8) References; (9) Legends of Figures and Tables; and (10) Tables and/or Figures.

    Manuscript Style
    The text should be double-spaced with generous margins. Times New Roman in 12 pt size is the preferred font style. Smaller spacing and font may be used for references, tables and figure legends. Subheadings may be used for clarification in the Material and Methods and Results sections, and must clearly differentiate from the main text using appropriate font style.

    The Title page hould include: (a) Full title (avoid abbreviations in the title); (b) Running title (for page heading, maximum of 50 characters); (c) All contributing authors with full name, title and affiliation; and (d) Corresponding author details with e-mail address (to which all decision letters and page proofs will be communicated).

    Should be 250 words or less and divided into subheadings: (1) Background; (2) Methods; (3) Results; (4) Discussion; and (5) Keywords. Only approved abbreviations may be used in the abstract without definition. Review Articles should include a "block style" nonstructured abstract.

    Graphical abstract

    A Graphical abstract is optional and should summarize the contents of the article in a concise, pictorial form designed to capture the attention of a wide readership online. Authors must provide images that clearly represent the work described in the article. Graphical abstracts should be submitted as a separate file in the online submission system. Image size: Please provide an image with a minimum of 531 × 1328 pixels (h × w) or proportionally more. The image should be readable at a size of 5 × 13 cm using a regular screen resolution of 96 dpi. Preferred file types: TIFF, EPS, PDF or MS Office files. See http://www.elsevier.com/graphicalabstracts for examples.
    Authors can make use of Elsevier's Illustration and Enhancement service to ensure the best presentation of their images also in accordance with all technical requirements: Illustration Service.

    Highlights

    Highlights are a short collection of bullet points that convey the core findings of the article. Highlights are optional and should be submitted in a separate file in the online submission system. Please use 'Highlights' in the file name and include 3 to 5 bullet points (maximum 85 characters, including spaces, per bullet point). See http://www.elsevier.com/highlights for examples.

    After the abstract, please include 3-10 keywords placed in alphabetical order and according to the Medical Subject Headings list of Index Medicus.

    Abbreviations used in the text should all be explained and listed on a separate page after the Abstract. A phrase is spelled out when used for the first time followed by an appropriate abbreviation in parentheses. Abbreviations must be spelled out in figure legends and footnotes of tables. If the article contains many non-standard abbreviations, a separate list with explanations must be provided. A list of standard abbreviations is given at our website.

    Include only those who have made a valuable contribution to the work presented but who do not qualify as authors, with their contribution described. This may include a patient population and funding bodies. Use plain language and avoid adjectives. If appropriate, funding for publication, for writing or editorial assistance may be added.

    Nomenclature and units

    Follow internationally accepted rules and conventions: use the international system of units (SI). If other quantities are mentioned, give their equivalent in SI. You are urged to consult IUPAP: Symbols, Units, Nomenclature and Fundamental Constants in Physics: http://www.iupap.org/ for further information.

    Math formulae

    Present simple formulae in the line of normal text where possible and use the solidus (/) instead of a horizontal line for small fractional terms, e.g., X/Y. In principle, variables are to be presented in italics. Powers of e are often more conveniently denoted by exp. Number consecutively any equations that have to be displayed separately from the text (if referred to explicitly in the text).

    Artwork

    Electronic Artwork
    The number of figures should be kept to a minimum. There should preferably not be any repetition/overlap of information given in figures and text. Figures should be submitted as separate files in their native file format in the best possible quality. Figures must be numbered and quoted consecutively in the text. Format: EPS or TIFF preferred. Resolution: 1200 dpi greyscale mode for black and white images such as graphs and log scales, 600 dpi greyscale mode for images such as gels or blots, and 300 dpi CMYK mode for colour images. A figure should be no larger than 160mm in width and 200mm in height at the appropriate resolution. Figures with resolution lower than specified will not reproduce correctly and could delay publication. For more information on submission guidelines for figures, visit http://www.elsevier.com/artworkinstructions.

    Color Artwork
    For illustrations in color in the printed version of the journal, the authors are required to pay the charges at USD 650 for the first color figure, and USD 100 for each additional color figure. However, illustrations may be printed in black and white in the hard copy and published in color in the online version of the journal without charge.

    Figure Captions
    Include the figure number in the figure caption (in Arabic numerals). Every panel appearing in the artwork should be defined in the legend. Define scale bars in figure legends, not in the artwork. Legends should be intelligible without reference to the text. Abbreviations defined in the text do not have to be defined again in the figure legends.

    Tables

    As with figures, the number of tables should be kept to a minimum and preferably not repeat information already found in the text. Tables should be intelligible without reference to the text and should supplement, not duplicate it. Each table should be included in the main manuscript file on a separate page after the references. If tables are uploaded separately, they must be in Word or Excel. The title should be typed above the first line of the table, and should include the number of the table (Roman numerals). Footnotes are indicated by using lower case alphabets as superscripts. P values are given as numbers (not as *, **, ***). Abbreviations defined in the text do not have to be defined again in the table key.

    References

    The total number of references should not exceed 100. Number references consecutively in the order in which they are first mentioned in the text. Identify references in the text, tables and legends by Arabic numerals within parentheses, i.e. (1). References cited in tables and legends to figures should be numbered in accordance with a sequence established by the first identification in the text of the particular table or illustration. The titles of the journals should be abbreviated according to the style used in Index Medicus. List all authors when 6 or fewer; when 7 or more, list the first six and add 'et al'. If a journal carries continuous pagination throughout a volume the month and issue number are omitted in the reference list. Page numbers are given as "2284-90", not "2284-2290." The use of abstracts in the list of references should be avoided. Manuscripts accepted but not yet published are designated 'in press.' Unpublished observations as well as manuscripts submitted but not yet accepted should be cited in the text only as 'unpublished observations' with the authors' initials, surname and institution as well as the year when the observation was made. The references must be verified by the authors against the original documents.

    Citation in text
    Please ensure that every reference cited in the text is also present in the reference list (and vice versa). Any references cited in the abstract must be given in full. Unpublished results and personal communications are not recommended in the reference list, but may be mentioned in the text. If these references are included in the reference list they should follow the standard reference style of the journal and should include a substitution of the publication date with either 'Unpublished results' or 'Personal communication'. Citation of a reference as 'in press' implies that the item has been accepted for publication and a copy of the title page of the relevant article must be submitted.

    Reference links
    Increased discoverability of research and high quality peer review are ensured by online links to the sources cited. In order to allow us to create links to abstracting and indexing services, such as Scopus, CrossRef and PubMed, please ensure that data provided in the references are correct. Please note that incorrect surnames, journal/book titles, publication year and pagination may prevent link creation. When copying references, please be careful as they may already contain errors. Use of the DOI is encouraged.

    Web references
    As a minimum, the full URL should be given and the date when the reference was last accessed. Any further information, if known (DOI, author names, dates, reference to a source publication, etc.), should also be given. Web references can be listed separately (e.g., after the reference list) under a different heading if desired, or can be included in the reference list.

    References in a special issue
    Please ensure that the words 'this issue' are added to any references in the list (and any citations in the text) to other articles in the same Special Issue.

    Reference formatting
    There are no strict requirements on reference formatting at submission. References can be in any style or format as long as the style is consistent. Where applicable, author(s) name(s), journal title/book title, chapter title/article title, year of publication, volume number/book chapter and the pagination must be present. Use of DOI is highly encouraged. The reference style used by the journal will be applied to the accepted article by Elsevier at the proof stage. Note that missing data will be highlighted at proof stage for the author to correct. If you do wish to format the references yourself they should be arranged according to the following examples:

    Reference style
    Text: Indicate references by number(s) in square brackets in line with the text. The actual authors can be referred to, but the reference number(s) must always be given.
    List: Number the references (numbers in square brackets) in the list in the order in which they appear in the text.
    Examples:
    Reference to a journal publication:
    [1] Van der Geer J, Hanraads JAJ, Lupton RA. The art of writing a scientific article. J Sci Commun 2010;163:51–9.
    Reference to a book:
    [2] Strunk Jr W, White EB. The elements of style. 4th ed. New York: Longman; 2000.
    Reference to a chapter in an edited book:
    [3] Mettam GR, Adams LB. How to prepare an electronic version of your article. In: Jones BS, Smith RZ, editors. Introduction to the electronic age, New York: E-Publishing Inc; 2009, p. 281–304.
    Note shortened form for last page number. e.g., 51–9, and that for more than 6 authors the first 6 should be listed followed by 'et al.' For further details you are referred to 'Uniform Requirements for Manuscripts submitted to Biomedical Journals' (J Am Med Assoc 1997;277:927–34) (see also http://www.nlm.nih.gov/bsd/uniform_requirements.html).

    Video data

    Elsevier accepts video material and animation sequences to support and enhance your scientific research. Authors who have video or animation files that they wish to submit with their article are strongly encouraged to include links to these within the body of the article. This can be done in the same way as a figure or table by referring to the video or animation content and noting in the body text where it should be placed. All submitted files should be properly labeled so that they directly relate to the video file's content. In order to ensure that your video or animation material is directly usable, please provide the files in one of our recommended file formats with a preferred maximum size of 50 MB. Video and animation files supplied will be published online in the electronic version of your article in Elsevier Web products, including ScienceDirect: http://www.sciencedirect.com. Please supply 'stills' with your files: you can choose any frame from the video or animation or make a separate image. These will be used instead of standard icons and will personalize the link to your video data. For more detailed instructions please visit our video instruction pages at http://www.elsevier.com/artworkinstructions. Note: since video and animation cannot be embedded in the print version of the journal, please provide text for both the electronic and the print version for the portions of the article that refer to this content.

    AudioSlides

    The journal encourages authors to create an AudioSlides presentation with their published article. AudioSlides are brief, webinar-style presentations that are shown next to the online article on ScienceDirect. This gives authors the opportunity to summarize their research in their own words and to help readers understand what the paper is about. More information and examples are available at http://www.elsevier.com/audioslides. Authors of this journal will automatically receive an invitation e-mail to create an AudioSlides presentation after acceptance of their paper.

    Supplementary data

    Cytotherapyaccepts supplementary data files to accompany the online article, allowing authors to support and enhance their papers. Supplementary materials may include additional images, tables, datasets, video clips, etc. All supplementary materials are subject to peer review, however, supplementary materials will not be edited, and will be posted as provided by the authors. There are no limitations for length, figures and references in Supplementary Materials. All Supplementary Materials should be cited within the text of the manuscript.

    Submission checklist

    The following list will be useful during the final checking of an article prior to sending it to the journal for review. Please consult this Guide for Authors for further details of any item.
    Ensure that the following items are present:
    One author has been designated as the corresponding author with contact details:
    • E-mail address
    • Full postal address
    • Phone numbers
    All necessary files have been uploaded, and contain:
    • Keywords
    • All figure captions
    • All tables (including title, description, footnotes)
    Further considerations
    • Manuscript has been 'spell-checked' and 'grammar-checked'
    • References are in the correct format for this journal
    • All references mentioned in the Reference list are cited in the text, and vice versa
    • Permission has been obtained for use of copyrighted material from other sources (including the Web)
    • Color figures are clearly marked as being intended for color reproduction on the Web (free of charge) and in print, or to be reproduced in color on the Web (free of charge) and in black-and-white in print
    • If only color on the Web is required, black-and-white versions of the figures are also supplied for printing purposes
    For any further information please visit our customer support site at http://support.elsevier.com.

    Submission to ScholarOne
    Authors must upload their files to ScholarOne in the following order: Approval for submission form (signed by every author); conflict of interest form (signed by co-author); title page, abstract and key words; body; references; tables (in Word); figures legends (in Word); and figure files (sequentially as Fig1, Fig2, Fig3, etc). The author approval for submission form and conflict of interest form can be found on the Cytotherapy Manuscript Central page.

    Additional Information

    Manufactured reagents: When referring to manufactured reagents, please list company name, city, state, and country in brackets following the name of the product/item.

    Use of statistics: The results should be quantified and presented with appropriate indicators of measurement error or uncertainty (e.g. confidence intervals). The mean and standard deviation (SD) should be given at a minimum; a sole reliance on the use of P values is not acceptable. The statistical method(s) and/or package used should also be stated. The Results should be presented in a logical sequence, and the Discussion should commence with a presentation of the major findings of the study and conclude with the implications and/or applications of the findings. Review Articles are structured more freely, yet the above instructions on statistics should be applied, when relevant.

    Use of the Digital Object Identifier

    The Digital Object Identifier (DOI) may be used to cite and link to electronic documents. The DOI consists of a unique alpha-numeric character string which is assigned to a document by the publisher upon the initial electronic publication. The assigned DOI never changes. Therefore, it is an ideal medium for citing a document, particularly 'Articles in press' because they have not yet received their full bibliographic information. Example of a correctly given DOI (in URL format; here an article in the journal Physics Letters B):
    http://dx.doi.org/10.1016/j.physletb.2010.09.059
    When you use a DOI to create links to documents on the web, the DOIs are guaranteed never to change.

    Proofs

    One set of page proofs (as PDF files) will be sent by e-mail to the corresponding author (if we do not have an e-mail address then paper proofs will be sent by post) or, a link will be provided in the e-mail so that authors can download the files themselves. Elsevier now provides authors with PDF proofs which can be annotated; for this you will need to download Adobe Reader version 9 (or higher) available free from http://get.adobe.com/reader. Instructions on how to annotate PDF files will accompany the proofs (also given online). The exact system requirements are given at the Adobe site: http://www.adobe.com/products/reader/tech-specs.html.
    If you do not wish to use the PDF annotations function, you may list the corrections (including replies to the Query Form) and return them to Elsevier in an e-mail. Please list your corrections quoting line number. If, for any reason, this is not possible, then mark the corrections and any other comments (including replies to the Query Form) on a printout of your proof and return by fax, or scan the pages and e-mail, or by post. Please use this proof only for checking the typesetting, editing, completeness and correctness of the text, tables and figures. Significant changes to the article as accepted for publication will only be considered at this stage with permission from the Editor. We will do everything possible to get your article published quickly and accurately – please let us have all your corrections within 48 hours. It is important to ensure that all corrections are sent back to us in one communication: please check carefully before replying, as inclusion of any subsequent corrections cannot be guaranteed. Proofreading is solely your responsibility. Note that Elsevier may proceed with the publication of your article if no response is received.

    Offprints

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