The Journal publishes peer-reviewed original articles emphasizing comparative and environmental biology, pharmacology, toxicology and endocrinology of animals. Adaptation and evolution as organizing principles are encouraged. Studies on mammalian biochemistry and physiology will be considered if approached in a comparative context.
The Journal receives editorial direction from all the major societies in the field (European Society for Comparative Physiology and Biochemistry,the Japanese Society for Comparative Physiology and Biochemistry, Canadian Society of Zoologists (CBP Section), the Society for Experimental Biology, the Society for Integrative and Comparative Biology (formerly the American Society for Zoologists), the Australian and New Zealand Society for Comparative Physiology and Biochemistry, the South American Society for Comparative Physiology & Biochemistry, the Russian Physiological Society, and the Chinese Association for Physiological Sciences)
PART A: MOLECULAR & INTEGRATIVE PHYSIOLOGY This section deals with molecular, cellular, integrative, and ecological physiology. Topics include bioenergetics, circulation, development, excretion, ion regulation, endocrinology, neurobiology, nutrition, respiration, and thermal biology. Study on regulatory mechanisms at any level of organization such as signal transduction and cellular interactions and control of behavior are encouraged.
PART B: BIOCHEMISTRY & MOLECULAR BIOLOGY covers biochemical and molecular biology aspects of metabolism, enzymology, regulation, nutrition, signal transduction, promoters, gene structure and regulation, metabolite and cell constituents, macromolecular structures, adaptational mechanisms and evolutionary principles.
PART C: TOXICOLOGY & PHARMACOLOGYis concerned with chemical and drug action at different levels of organization, biotransformation ofxenobiotics, mechanisms of toxicity, including reactive oxygenspecies and carcinogenesis, endocrine disruptors, natural products chemistry, and signal transduction with a molecular approach to these fields.
PART D: GENOMICS & PROTEOMICScovers the broader comprehensive approaches to comparative biochemistry and physiology that can be generally termed as " -omics", e.g., genomics, functional genomics (transcriptomics), proteomics, metabolomics, and underlying bioinformatics. Papers dealing with fundamental aspects and hypotheses in comparative physiology and biochemistry are encouraged rather than studies whose main focus is purely technical or methodological.