Chemistry & Biology
Previously published by Current Trends. Now published by Cell Press
Chemistry & Biology publishes reports of novel investigations in all areas at the interface of chemistry and biology. Chemistry & Biology strongly encourages submission of articles in which chemical tools are used to provide unique insight into biological function and mechanism. Studies that illustrate the underlying chemistry of biological processes will also be viewed favorably. Other relevant studies of interest to chemists and biologists will also be considered. In general, to be considered suitable for publication in this journal, investigations that primarily have a genetic, computational, or theoretical focus must contain substantiating experimental data. All articles should not only be of significance to the immediate field but should also be of interest to our diverse readership from the broad chemical-biology community.
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Editors: Ronald Breaker , Michael Famulok , Peter Seeberger , Kevan Shokat , Wolfgang Wohlleben
Impact factor: 5.829
5 year impact factor: 5.971
Imprint: Cell Press
ISSN: 1074-5521
Most cited
Top 10 Cited (articles published in the last five years)
Extracted from Scopus (on Mon May 20)261 Blankman, J.L. | Simon, G.M. | Cravatt, B.F. A Comprehensive Profile of Brain Enzymes that Hydrolyze the Endocannabinoid 2-Arachidonoylglycerol Chemistry and Biology, Volume 14, Issue 12, 2007-12-26, Pages 1347-1356 189 Clausell-Tormos, J. | Lieber, D. | Baret, J.-C. | El-Harrak, A. | Miller, O.J. | Frenz, L. | Blouwolff, J. | Humphry, K.J. | Köster, S. | Duan, H. | Holtze, C. | Weitz, D.A. | Griffiths, A.D. | Merten, C.A. Droplet-Based Microfluidic Platforms for the Encapsulation and Screening of Mammalian Cells and Multicellular Organisms Chemistry and Biology, Volume 15, Issue 5, 2008-05-19, Pages 427-437 167 Hong, S. | Leroueil, P.R. | Majoros, I.J. | Orr, B.G. | Baker Jr., J.R. | Banaszak Holl, M.M. The Binding Avidity of a Nanoparticle-Based Multivalent Targeted Drug Delivery Platform Chemistry and Biology, Volume 14, Issue 1, 2007-01-01, Pages 107-115 166 Gautier, A. | Juillerat, A. | Heinis, C. | Corrêa Jr., I.R. | Kindermann, M. | Beaufils, F. | Johnsson, K. An Engineered Protein Tag for Multiprotein Labeling in Living Cells Chemistry and Biology, Volume 15, Issue 2, 2008-02-22, Pages 128-136 152 Pommier, Y. | Leo, E. | Zhang, H. | Marchand, C. DNA topoisomerases and their poisoning by anticancer and antibacterial drugs Chemistry and Biology, Volume 17, Issue 5, 2010-07-07, Pages 421-433 121 Ahn, K. | Johnson, D.S. | Mileni, M. | Beidler, D. | Long, J.Z. | McKinney, M.K. | Weerapana, E. | Sadagopan, N. | Liimatta, M. | Smith, S.E. | Lazerwith, S. | Stiff, C. | Kamtekar, S. | Bhattacharya, K. | Zhang, Y. | Swaney, S. | Van Becelaere, K. | Stevens, R.C. | Cravatt, B.F. Discovery and Characterization of a Highly Selective FAAH Inhibitor that Reduces Inflammatory Pain Chemistry and Biology, Volume 16, Issue 4, 2009-04-24, Pages 411-420 114 Deacon, S.W. | Beeser, A. | Fukui, J.A. | Rennefahrt, U.E.E. | Myers, C. | Chernoff, J. | Peterson, J.R. An Isoform-Selective, Small-Molecule Inhibitor Targets the Autoregulatory Mechanism of p21-Activated Kinase Chemistry and Biology, Volume 15, Issue 4, 2008-04-21, Pages 322-331 101 Cochrane, J.C. | Lipchock, S.V. | Strobel, S.A. Structural Investigation of the GlmS Ribozyme Bound to Its Catalytic Cofactor Chemistry and Biology, Volume 14, Issue 1, 2007-01-01, Pages 97-105 99 Schneider, C. | Pratt, D.A. | Porter, N.A. | Brash, A.R. Control of Oxygenation in Lipoxygenase and Cyclooxygenase Catalysis Chemistry and Biology, Volume 14, Issue 5, 2007-05-29, Pages 473-488 97 Diggle, S.P. | Matthijs, S. | Wright, V.J. | Fletcher, M.P. | Chhabra, S.R. | Lamont, I.L. | Kong, X. | Hider, R.C. | Cornelis, P. | Cámara, M. | Williams, P. The Pseudomonas aeruginosa 4-Quinolone Signal Molecules HHQ and PQS Play Multifunctional Roles in Quorum Sensing and Iron Entrapment Chemistry and Biology, Volume 14, Issue 1, 2007-01-01, Pages 87-96 - View all items
Most downloaded
Most Read Articles - counted by Article downloads on SciVerse ScienceDirect in the period 01 April 2002 to 30 April 2013
Mon May 201 Anna E Speers | Benjamin F Cravatt Profiling Enzyme Activities In Vivo Using Click Chemistry Methods Chemistry & Biology, Volume 11, Issue 4, April 2004, Pages 535-546 2 Zachary A. Knight | Kevan M. Shokat Features of Selective Kinase Inhibitors Chemistry & Biology, Volume 12, Issue 6, June 2005, Pages 621-637 3 Matthew P Coghlan | Ainsley A Culbert | Darren AE Cross | Stacey L Corcoran | John W Yates | Nigel J Pearce | Oliver L Rausch | Gregory J Murphy | Paul S Carter | Lynne Roxbee Cox | David Mills | Murray J Brown | David Haigh | Robert W Ward | David G Smith | Kenneth J Murray | Alastair D Reith | Julie C Holder Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription Chemistry & Biology, Volume 7, Issue 10, October 2000, Pages 793-803 4 Jochen Schust | Bianca Sperl | Angela Hollis | Thomas U. Mayer | Thorsten Berg Stattic: A Small-Molecule Inhibitor of STAT3 Activation and Dimerization Chemistry & Biology, Volume 13, Issue 11, November 2006, Pages 1235-1242 5 Yves Pommier | Elisabetta Leo | HongLiang Zhang | Christophe Marchand DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs Chemistry & Biology, Volume 17, Issue 5, 28 May 2010, Pages 421-433 6 Laurent Meijer | Alexios-Leandros Skaltsounis | Prokopios Magiatis | Panagiotis Polychronopoulos | Marie Knockaert | Maryse Leost | Xiaozhou P. Ryan | Claudia Alin Vonica | Ali Brivanlou | Rana Dajani | Claudia Crovace | Cataldo Tarricone | Andrea Musacchio | S.Mark Roe | Laurence Pearl | Paul Greengard GSK-3-Selective Inhibitors Derived from Tyrian Purple Indirubins Chemistry & Biology, Volume 10, Issue 12, December 2003, Pages 1255-1266 7 Amy C. Anderson The Process of Structure-Based Drug Design Chemistry & Biology, Volume 10, Issue 9, September 2003, Pages 787-797 8 Arnaud Gautier | Alexandre Juillerat | Christian Heinis | Ivan Reis Corrêa Jr. | Maik Kindermann | Florent Beaufils | Kai Johnsson An Engineered Protein Tag for Multiprotein Labeling in Living Cells Chemistry & Biology, Volume 15, Issue 2, 22 February 2008, Pages 128-136 9 Min-Jia Tan | Ji-Ming Ye | Nigel Turner | Cordula Hohnen-Behrens | Chang-Qiang Ke | Chun-Ping Tang | Tong Chen | Hans-Christoph Weiss | Ernst-Rudolf Gesing | Alex Rowland | David E. James | Yang Ye Antidiabetic Activities of Triterpenoids Isolated from Bitter Melon Associated with Activation of the AMPK Pathway Chemistry & Biology, Volume 15, Issue 3, 21 March 2008, Pages 263-273 10 Ipsita Roy | Munishwar Nath Gupta Smart Polymeric Materials Emerging Biochemical Applications Chemistry & Biology, Volume 10, Issue 12, December 2003, Pages 1161-1171 - View all items
Recent articles
Mon May 201 Byron Hetrick | Min Suk Han | Luke A. Helgeson | Brad J. Nolen Small Molecules CK-666 and CK-869 Inhibit Actin-Related Protein 2/3 Complex by Blocking an Activating Conformational Change Chemistry & Biology, Available online 25 April 2013 2 Farzana Miah | Hendrik Koliwer-Brandl | Martin Rejzek | Robert A. Field | Rainer Kalscheuer | Stephen Bornemann Flux through Trehalose Synthase Flows from Trehalose to the Alpha Anomer of Maltose in Mycobacteria Chemistry & Biology, Volume 20, Issue 4, 18 April 2013, Pages 487-493 3 Carrie Shiau | Michael J. Trnka | Alen Bozicevic | Idelisse Ortiz Torres | Bassem Al-Sady | Alma L. Burlingame | Geeta J. Narlikar | Danica Galonić Fujimori Reconstitution of Nucleosome Demethylation and Catalytic Properties of a Jumonji Histone Demethylase Chemistry & Biology, Volume 20, Issue 4, 18 April 2013, Pages 494-499 4 Neda Nasheri | Michael Joyce | Yanouchka Rouleau | Pengyu Yang | Shao Yao | D. Lorne Tyrrell | John Paul Pezacki Modulation of Fatty Acid Synthase Enzyme Activity and Expression during Hepatitis C Virus Replication Chemistry & Biology, Volume 20, Issue 4, 18 April 2013, Pages 570-582 5 Carolin Anders | Yusuke Higuchi | Kristin Koschinsky | Maria Bartel | Benjamin Schumacher | Philipp Thiel | Hajime Nitta | Regina Preisig-Müller | Günter Schlichthörl | Vijay Renigunta | Junko Ohkanda | Jürgen Daut | Nobuo Kato | Christian Ottmann A Semisynthetic Fusicoccane Stabilizes a Protein-Protein Interaction and Enhances the Expression of K+ Channels at the Cell Surface Chemistry & Biology, Volume 20, Issue 4, 18 April 2013, Pages 583-593 6 Takaaki Taguchi | Masaki Yabe | Hitomi Odaki | Miki Shinozaki | Mikko Metsä-Ketelä | Takao Arai | Susumu Okamoto | Koji Ichinose Biosynthetic Conclusions from the Functional Dissection of Oxygenases for Biosynthesis of Actinorhodin and Related Streptomyces Antibiotics Chemistry & Biology, Volume 20, Issue 4, 18 April 2013, Pages 510-520 7 Marcel Zimmermann | Julian D. Hegemann | Xiulan Xie | Mohamed A. Marahiel The Astexin-1 Lasso Peptides: Biosynthesis, Stability, and Structural Studies Chemistry & Biology, Volume 20, Issue 4, 18 April 2013, Pages 558-569 8 Steven H.L. Verhelst Probing Functional Tyrosines Chemistry & Biology, Volume 20, Issue 4, 18 April 2013, Pages 457-458 9 Kiril Mishev | Wim Dejonghe | Eugenia Russinova Small Molecules for Dissecting Endomembrane Trafficking: A Cross-Systems View Chemistry & Biology, Volume 20, Issue 4, 18 April 2013, Pages 475-486 10 Wendy Wolfson Epigenetic Cancer Therapies Emerge out of the Lab into the Limelight Chemistry & Biology, Volume 20, Issue 4, 18 April 2013, Pages 455-456 - View all items
