Table of ContentsVaccines and Diagnostics: Historic and Contemporary Perspectives:M.C. Horzinek, Vaccination--A Philosophical View.I. Tizzard, Grease, Anthraxgate, and Kennel Cough: A Revisionist History of Veterinary Vaccines.J.F. Evermann and I.S. Eriks, Diagnostic Medicine: The Challenge of Differentiating Infection from Disease and Making Sense for the Veterinary Clinician.Concepts in Immunology and Vaccinology:B.N. Wilke and B.A. Mallard, Genetic Effects on Vaccination.M.E. Cook, Nutritional Effects on Vaccination.M.G. Kehrli, J.L. Burton, B.J. Nonnecke, and E.K. Lee, Effects of Stress on Leukocyte Trafficking and Immune Responses: Implication for Vaccination.M.P. Murtaugh and D.L. Foss, The Role of Macrophage Cytokines in Mucosal Adjuvanticity.M.W. Russell, H-Y. Wu, G. Hajishengallis, S.K. Hollingshead, and S. Michalek, Cholera Toxin B Subunit as an Immunomodulator for Muscosal Vaccine Delivery.P.L. Nara, Deceptive Imprinting: Insights into Mechanisms of Immune Evasion and Vaccine Development.I.M. Orme, Vaccination Against Tuberculosis: Recent Progress.M. Sheppard, Viral Vectors for Veterinary Vaccines.L.A. Babiuk, J. Lewis, S. van den Hurk, and R. Braun, DNA Immunization: Present and Future.Bovine Vaccines and Diagnostics:J.T. van Oirschot, Bovine Viral Vaccines, Diagnostics and Eradication: Past, Present and Future.L. B. Corbeil, Immunization and Diagnosis in Bovine Reproductive Tract Infections.E.N.T. Meeusen and J.F. Maddox, Progress and Expectations for Helminth Vaccines.R.J. Yancey, Jr., Vaccines and Diagnostic Methods for Bovine Mastitis: Fact and Fiction.C.J. Howard, R.A. Collins, P. Sopp, G.P. Brooke, L.S. Kwong, K.R. Parsons, V. Weynants, J.J. Letesson, and G.P. Bembridge, T Cell Responses and the Influence of Dendritic Cells in Cattle.Canine and Feline Vaccines:L.E. Carmichael, Canine Viral Vaccines at a Turning Point: A Personal Perspective.M. Appel, Forty Years of Canine Vaccination.M.J. Hosie and O. Jarrett, Analysis of the Protective Immunity Induced by FIV Vaccination.C.W. Olsen, Vaccination of Cats Against Emerging and Re-Emerging Zoonotic Pathogens.F.W. Scott, Evaluation of Risks and Benefits Associated with Vaccination Against Coronavirus Infections in Cats. Equine Vaccines and Diagnostics:P. Desmettre, Diagnosis and Prevention of Equine Infections Diseases: Present Status-Potential & Challenges for the Future.J.A. Mumford, The Equine Influenza Surveillance Programme.D.W. Horohov, C.E. Swidinski, T.R. Klei, R.W. Folsom, S.S. Pourciau, A Chapman, M.R. Chapman, R.M. Moore, J.R. McClure, and H.W. Taylor, Vaccination Against Strongyles vulgaris in Ponies: Comparison of the Humoral and Cytokine Responses of Vaccinates and Nonvaccinates.B. Morein, M. Villacres-Eriksson, J. Ekstrom, K. Hu, S. Behboudi, and K. Lovgren-Bengtsson, ISCOM--A Delivery System for Neonates and for Mucosal Administration.P.S. Morley, An Epidemiologic Approach to Evaluating the Importance of Immunoprophylaxis.Porcine Vaccines:L. Backstrom, Present Use and Experiences of Swine Vaccines.L.J. Saif, Enteric Viral Infections of Pigs and Strategies for Induction of Mucosal Immunity.F. Zuckermann, S. Martin, R.J. Husmann, and J. Brandt, The Use of IL-12 to Enhance the Cellular Immune Response of Swine to an Inactivated Herpesvirus Vaccine.D.N. Tripathy, Swinepox Virus as a Vaccine Vector for Swine Pathogens.Poultry Vaccines:J.M. Sharma, Introduction of Poultry Vaccines and Immunity.C.A. Ricks, A. Avakian, T. Bryan, R. Gildersleeve, E. Haddad, R. Ilich, S. King, L. Murray, P. Phelps, R. Poston, C. Whitfill, and C. Williams, In Ovo Vaccination Technology.M.W. Jackwood, Current and Future Recombinant Viral Vaccines for Poultry.Fish, Exotic and Wildlife Vaccines:P.H. Klesius and C.A. Shoemaker, The Development and Use of Modified Live Edwardsiella ictaluri Vaccine Against Enteric Septicemia of Catfish.S. Vinitnantharat, K. Gravningen, and E. Greger, Fish Vaccines.J.F. Curlee, Cross Species Vaccination in Wild and Exotic Animals.J.R. Gorham, Some Experiments and Field Observations of Distemper in Mink and Ferrets.Regulation, Licensing, and Standardization of Vaccines and Diagnostics:D.A. Espeseth and T.J. Myers, Authorities and Procedures for Licensing Veterinary Biological Products in the United States.P.P. Pastoret and F. Falize, Licensing Procedure for Immunological Veterinary Medicinal Production in the European Union.D. Gaudry, International Association of Biological Standardization and International Harmonization.P. Vannier, Technical Requirements for the Licensing of Pseudorabies (Aujesky's Disease) Vaccines in the European Union.D.L. Sutton, Specific Licensing Considerations for Modified Live Pseudorabies Vaccines in the United States.D.R. Hustead, Why Do Vaccine Labels Say the Funny Things They Do?P.D. Eckersall, S. Duthie, M.J.M. Toussaint, E. Gruys, P. Heegaard, M. Alava, C. Lipperheide, and F. Madec, Standardization of Diagnostic Assays for Animal Acute Phase Proteins.S. Martinod, Vaccination Practices in Veterinary Medicine: Standardization vs. Tailored to Needs?P.F. Wright, International Harmonization Standards for Diagnostic Tests and Vaccines: Role of the Office International des Epizooties (OIE).Adverse Vaccine Reactions and Failures and Postmarketing Surveillance:J.A. Roth, Mechanistic Bases for Adverse Vaccine Reactions and Vaccine Failures.L.T. Glickman, Weighing the Risks and Benefits of Vaccination.W.J. Dodds, More Bumps on the Vaccine Road.H. Hogenesch, J. Azcona-Olivera, C. Scott-Moncrieff, P.W. Snyder, and L.T. Glickman, Vaccine-Induced Autoimmunity in the Dog.D. Siev, An Introduction to Analytical Methods for the Postmarketing Surveillance of Veterinary Vaccines.Subject Index.