Veterinary Toxicology

Basic and Clinical Principles

Edited by
  • Ramesh Gupta, Murray State University, Breathitt Veterinary Center, Hopkinsville, KY, USA
  • Ramesh Gupta, Murray State University, Breathitt Veterinary Center, Hopkinsville, KY, USA

Veterinary Toxicology is a unique single reference that teaches the basic principles of veterinary toxicology to any student at the DVM, MS or PhD level and will continue to serve as a clinical reference for practicing veterinary toxicologists, poison control centers, marine biologists, environmentalists, and animal scientists. While most comparable texts are primarily directed toward the field of human toxicology, this is the one text needed to thoroughly prepare future veterinarians on the newest approaches for diagnosing poisoning cases in all animals from chemicals and plants of a diverse nature as a result of inadvertent, accidental, or malicious intents. Many chapters are provided on topics not covered in any previous books such as target organ toxicity, radiation and radioactive materials, FDA regulatory issues, and ethics in veterinary toxicology.

Audience
Professors and students (DVM, MS, or PhD level) in the area of veterinary toxicology, practicing veterinarians, veterinary toxicologists, poison control centers, marine biologists, environmentalists, animal scientists, schools/ colleges of veterinary medicine, and college and university libraries

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Published: March 2007

Imprint: Academic Press

ISBN: 978-0-12-370467-2

Reviews

  • "A lot of in-depth information in 1 text, including some not readily available elsewhere. A number of topics included are contemporary, which increases its value for toxicologists who are not specifically veterinary toxicologists. There is more extensive coverage of pathology than is typical of toxicology texts."
    - Marion Ehrich, PhD, DABT, in Journal of American Veterinary Medical Association

     "A useful source of information for the veterinary clinician, student, and toxicologist. The strengths of this book comprise the inclusion of large and small animal species; the broad range of topics encompassing regulatory, diagnostic, pathologic, and clinical toxicology; and the affordable cost. A nice addition to any veterinarian’s library and is well worth the price."
    - The Canadian Veterinary Journal

    "A unique single reference that teaches the basic principles of veterinary toxicology to any student at the DVM, MS or PhD level and will continue to serve as a clinical reference for practicing veterinary toxicologists, poison control centers, marine biologists, environmentalists, and animal scientists. While most comparable texts are primarily directed toward the field of human toxicology, this is the one text needed to thoroughly prepare future veterinarians on the newest approaches for diagnosing poisoning cases in all animals from chemicals and plants of a diverse nature as a result of inadvertent, accidental, or malicious intents. Many chapters are provided on topics not covered in any previous books such as target organ toxicity, radiation and radioactive materials, FDA regulatory issues, and ethics in veterinary toxicology...many newer topics including chemicals of terrorism, estrogenic toxicants, and nanoparticles are included. Overall, the information provided is well organized and comprehensive...generous and relevant references at the end of each chapter allow the opportunity to further pursue each topic.

    This book can be considered a cornerstone upon which a deeper understanding of the issues and individual toxicants in veterinary toxicology can be based. The topics covered are of interest to not only toxicologists and researchers, but also to clinicians who do not have an extensive background in toxicology. This book is a fine addition to any veterinary professional's library, but it is important to realize that after becoming familiar with this material, the readers' interests will then determine if more focused, additional resources are needed."
    - Paul A. Eubig, DVM, MS, DABT (University of Illinois College of Veterinary Medicine), in DOODY'S REVIEWS

    "The book is reasonably priced, rich and rewarding and I can warmly recommend it as a useful reference book to all practicing toxicologists."
    - Roy Forster, CIT, France - The British Toxicology Society Newsletter


Contents

  • ForewordGeneralIntroduction General Principles of Veterinary ToxicologyPharmacokinetics in Veterinary ToxicologyPhysiologically Based Pharmacokinetic Modeling Mechanism of ToxicityToxicological Testing: In Vitro & In Vivo ModelsEpidemiology of Poisoning CasesChemical TerrorismRegulatory Considerations in Veterinary ToxicologyLegal & Ethical Considerations in Veterinary ToxicologyOrgan ToxicityNervous System ToxicityHepatic ToxicityRenal ToxicityRespiratory ToxicityCardiovascular ToxicityEndocrine DisruptionReproductive ToxicityPlacental Toxicity Dermal ToxicityHematopoietic System ToxicityImmunotoxicityNanoparticles, Radiation & CarcinogenesisBiomedical responses & Toxicity of NanoparticlesOxidative Stress & NeurodegenerationRadiation & Radioactive MaterialsCarcinogenesis: Molecular mechanism & ModelsDrugs of Use & AbuseToxicity of Over -the-Counter DrugsToxicity of Drugs of AbuseMetals & MicronutrientsArsenicCadmiumCopperFluorideIronLeadMercuryMolybdenumPhosphorusSeleniumSodium ChlorideSulfurZincOther Elements (Aluminum, Chromium, Cobalt, Iodine, Manganese, Tin)InsecticidesOrganophosphates & CarbamatesOrganochlorinesPyrethrins, Pyrethroids & others InsecticidesRodenticidesAnticoagulant RodenticidesNon-anticoagulant Rodenticides Herbicides & FungicidesToxicity of HerbicidesToxicity of FungicidesToxic Gases & SmokeToxic GasesSmoke InhalationIndustrial ToxicantsEthylene glycol and OxalatesDetergents, Soaps, Surfactants & Other Household ProductsPetroleum ProductsDioxin, PCBs & PBBsEnvironmental ToxicologyAvian ToxicologyEcotoxicityAquatic ToxicologyBlue-Green Algae ToxinsToxicology of Marine ToxinsBacterial ToxinsBotulinum ToxinEnterotoxinsPoisonous & Venomous OrganismsCaterpillars & Mare Reproductive Loss SyndromeZootoxinsEstrogenic ToxicantsPhytoestrogensChemical-Induced EstrogenecityPoisonous PlantsPoisonous PlantsCyanogenic PlantsNitrate & Nitrite Accumulating PlantsFescue ToxicosisMushroom ToxinsCotton Seed ToxicityTaxus PoisoningMycotoxinsAflatoxinsTrichothecenesVomitoxinZearalenoneFumonisinsPenicillium MycotoxinsTremorgenic MycotoxinsSlaframineErgotFeed & Water ContaminantsIonophoresUrea & Ammonia Chicken LitterWater Quality & ContaminantsDiagnostic ToxicologyAnalytical Toxicology PrinciplesSample Submission for Toxicological AnalysisAnalytical Instrumentation Applied in the Veterinary Toxicology LaboratoryToxicoproteomics in Diagnostic ToxicologyMicroscopic Analysis of Toxic Substances in Feed & IngestaRole of Pathology in Diagnosing Toxicological CasesInterpretation of Analytical ResultsTherapeutic MeasuresPrevention & Treatment of Poisonings

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