Vertebrate Endocrinology book cover

Vertebrate Endocrinology

Vertebrate Endocrinology represents more than just a treatment of the endocrine system-it integrates hormones with other chemical bioregulatory agents not classically included with the endocrine system. It provides a complete overview of the endocrine system of vertebrates by first emphasizing the mammalian system as the basis of most terminology and understanding of endocrine mechanisms and then applies that to non-mammals. The serious reader will gain both an understanding of the intricate relationships among all of the body systems and their regulation by hormones and other bioregulators, but also a sense of their development through evolutionary time as well as the roles of hormones at different stages of an animal's life cycle.

Hardbound, 580 Pages

Published: June 2013

Imprint: Academic Press

ISBN: 978-0-12-394815-1


  • "…what makes this book particularly useful for many aspects of the study of life science lies in its synthesis, its making of links between different aspects of biology."--The Biologist,Vol 61, No 6

    "This book will be useful for graduate students interested in comparative endocrinology…As an instructor of veterinary endocrinology, I found this book to be a good source for both illustrations and basic information, and a complement for clinical and animal management discussions in endocrinology."--Journal of American Veterinary Medicine Association, December 15, 2013
    "…constitutes a major and unique contribution to this area…contains a wealth of factual information…[and] admirably succeeds in stimulating the scientific curiosity of readers and in conveying a sense of fascination for the intricate mechanisms and importance of endocrinology."--General and Comparative Endocrinology
    "…a good text for comparative endocrinology classes or classes composed of students from a wide variety of disciplines…this book is well written and organized. Concepts are explained in a manner that should be easily understandable to beginning endocrinology students."--Trends in Endocrinology and Metabolism


  • 1. An Overview of Chemical Bioregulation in Vertebrates

    I. The Comparative Vertebrate Approach

    II. The Origins of Bioregulation

    III. Categories of Bioregulators

    IV. General Organization of Bioregulatory Systems

    V. Cell and Tissue Organization of Bioregulatory Systems

    VI. Homeostasis

    VII. Organization and Goals for This Textbook

    Study Questions

    Suggested Reading

    2. Methods to Study Bioregulation

    I. The Scientific Method

    II. Methods of Endocrine Analysis

    III. Molecular Biology and Bioregulation

    IV. Animal Models

    Study Questions

    Suggested Reading

    3. Synthesis, Metabolism, and Actions of Bioregulators

    I. Amino Acids, Amines, Peptides, and Proteins

    II. Steroid Bioregulators

    III. Thyroid Hormones

    IV. Eicosanoids

    V. Summary

    Study Questions

    Suggested Reading

    4. Organization of the Mammalian Hypothalamus-Pituitary Axes

    I. The Mammalian Pituitary

    II. The Mammalian Hypothalamus

    III. Tropic Hormones of the Adenohypophysis

    IV. Regulation of Tropic Hormone Secretion in Mammals

    V. The Nonapeptide Hormones

    VI. The Pineal Gland

    VII. Clinical Aspects of the NeuroendocrineSystem

    VIII. Summary

    Study Questions

    Suggested Readings

    5. The Hypothalamuse Pituitary System in Non-Mammalian Vertebrates

    I. The Pituitary Gland of Fishes: Anatomical Considerations

    II. The Pituitary of Tetrapod Vertebrates: Anatomical Considerations

    III. The Hypothalamus of Non-Mammalian Vertebrates

    IV. Tropic Hormones of Non-Mammalian Vertebrates

    V. Comparative Aspects of Hypothalamic Control of Pituitary Function in Non-Mammals

    VI. Nonapeptide Neurohormones of the Non-Mammalian Pars Nervosa

    VII. The Epiphysial Complex of Non-Mammals

    VIII. Summary

    Study Questions

    Suggested Reading

    6. The Hypothalamus-Pituitary-Thyroid (HPT) Axis of Mammals

    I. Some Historical Aspects of Thyroid Physiology

    II. Development and Organization of the Mammalian Thyroid Gland

    III. Synthesis, Secretion, Action, and Metabolism of Thyroid Hormones

    IV. Factors That Influence Thyroid Function in Mammals

    V. Biological Actions of Thyroid Hormones in Mammals

    VI. Clinical Aspects of Thyroid Function

    VII. Summary

    Study Questions

    Suggested Reading

    7. The Hypothalamuse-Pituitary-Thyroid (HPT) Axis of Non-Mammalian Vertebrates

    I. Evolution of the Thyroid Gland and Its Functions

    II. Comparative Thyroid Physiology

    III. Summary

    Study Questions

    Selected Reading

    8. The Mammalian Adrenal Glands: Cortical and Chromaffin Cells

    I. The Mammalian Adrenal Cortex

    II. Biosynthesis and Transport of Corticosteroids

    III. Secretion and Actions of Glucocorticoids

    IV. Allostasis and Allostatic Load

    V. Aldosterone: The Principal Mammalian ""Mineralocorticoid""

    VI. Endocrine Disruption of Adrenal Cortex Function

    VII. Clinical Aspects of the Adrenal Axis

    VIII. The Mammalian Adrenal Medulla

    IX. Summary

    Study Questions

    Suggested Reading

    9. Comparative Aspects of Vertebrate Adrenals

    I. Comparative Aspects of Adrenocortical Tissue

    II. Physiological Roles for Corticosteroids in Non-Mammalian Vertebrates

    III. RenineAngiotensin System in Non-Mammals

    IV. Natriuretic Peptides (NPs) in Non-Mammalian Vertebrates

    V. Evolution of Chromaffin Tissue and Adrenal Medullary Hormones

    VI. Endocrine Disruption of Corticosteroid Functions in Non-Mammalian Vertebrates

    VII. Summary

    Study Questions

    Suggested Reading

    10. The Endocrinology of Mammalian Reproduction

    I. General Features of Mammalian Reproduction

    II. Reproduction in Monotremes and Marsupials

    III. Reproduction in Eutherian Mammals

    IV. Endocrine Regulation in Eutherian Males

    V. Endocrine Regulation in Eutherian Females

    VI. Reproductive Cycles in Selected Eutherian Females

    VII. Endocrine Disruptors and Mammalian Reproduction

    VIII. Major Human Endocrine Disorders Related to Reproduction

    IX. Summary

    Study Questions

    Suggested Reading

    11. Comparative Aspects of Vertebrate Reproduction

    I. Some General Features of Vertebrate Reproduction

    II. Reproduction in Agnathan Fishes: Cyclostomes

    III. Reproduction in Chondrichthyean Fishes

    IV. Reproduction in Bony Fishes

    V. Reproduction in Amphibians

    VI. Reproduction in Reptiles

    VII. Reproduction in Birds

    VIII. Endocrine Disruption of Reproduction in Non-Mammalian Vertebrates

    IX. Summary

    Study Questions

    Suggested Reading

    12. Chemical Regulation of Feeding, Digestion and Metabolism

    I. Regulation of Feeding

    II. Regulation of Digestion

    III. The Mammalian Pancreas

    IV. Hormones Regulating Mammalian Metabolism

    V. Clinical Aspects of Pancreatic Function

    VI. Summary

    Study Questions

    Suggested Reading

    13. Comparative Aspects of Feeding, Digestion, and Metabolism

    I. Hormones and Feeding in Non-Mammals

    II. Hormones and Digestion in Non-Mammals

    III. Comparative Aspects of the Endocrine Pancreas

    IV. Summary

    Study Questions

    Suggested Reading

    14. Regulation of Calcium and Phosphate Homeostasis

    I. Importance of Calcium and Phosphate

    II. Bone Formation and Resorption in Mammals

    III. Endocrine Regulation of Calcium and Phosphate Homeostasis in Mammals

    IV. Major Clinical Disorders Associated with Calcium Metabolism

    V. Calcium and Phosphate Homeostasis in Non-Mammalian Vertebrates

    VI. Summary

    Study Questions

    Suggested Reading



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