Vaccines book cover


Expert Consult - Online and Print

2013 BMA Medical Book Awards Highly Commended in Public Health!

Apply the latest vaccination knowledge with a reference that Bill Gates calls "an indispensable guide to the enhancement of the well-being of our world." Inside Vaccines, you’ll find comprehensive and current coverage of every aspect of vaccination, from the development of each vaccine to its use in reducing disease. This medical reference book offers the expert information you need to apply the very latest techniques and information in your practice!

Hardbound, 1570 Pages

Published: October 2012

Imprint: Saunders

ISBN: 978-1-4557-0090-5


  • "Widely regarded as The Bible for vaccinologists… the book remains the work of reference that every person working in the field of vaccines and those with an interest in infectious diseases should have."

    The Lancet: Infectious Diseases, June 2008

    "For anyone wishing to know everything important about existing vaccines, this book provides an indispensable source of authoritative information."

    Immunology News, February 2009

    "The new foreword by Bill Gates emphasizes the importance of vaccines and the value of this book.  This is the leading reference that covers all aspects of vaccinology.  There are no comparable books available.  In the rapidly evolving field of vaccinology, this new edition is essential."

    - Archana NMI Chatterjee, MD PhD, Creighton University

    5 Star - Doody's Rating, March 2013 


  • Contents

    Foreword ix

    Preface to the first edition x

    Preface to the sixth edition x

    Preface by Editor in Chief xi

    List of Contributors xii

    Dedication xix

    Acknowledgements xix

    SECTION 1: General aspects of vaccination

    1 A short history of vaccination 1

    Susan L. Plotkin, Stanley A. Plotkin

    2 Vaccine immunology 14

    Claire-Anne Siegrist

    3 The vaccine industry 33

    R. Gordon Douglas, Vijay B. Samant

    4 Vaccine manufacturing 44

    Phillip L. Gomez, James M. Robinson, Joseph A. Rogalewicz

    5 Evolution of adjuvants across the centuries 58

    Nathalie Garçon, Stanley Hem, Martin Friede

    6 Vaccine additives and manufacturing residuals in the United States:

    licensed vaccines 71

    Theresa M. Finn, William Egan

    7 Passive immunization 80

    E. Richard Stiehm, Margaret A. Keller

    8 General immunization practices 88

    Andrew T. Kroger, William L. Atkinson, Larry K. Pickering

    SECTION 2: Licensed vaccines

    9 Adenovirus vaccines 113

    Gregory C. Gray

    10 Anthrax vaccines 127

    Arthur M. Friedlander, John D. Grabenstein, Phillip S. Brachman

    11 Cholera vaccines 141

    John D. Clemens, Sunheang Shin, Binod K. Sah, David A. Sack

    12 Diphtheria toxoid 153

    Tejpratap S. P. Tiwari, Melinda Wharton

    13 Haemophilus influenzae vaccines 167

    Aruna Chandran, James P. Watt, Mathuram Santosham

    14 Hepatitis A vaccines 183

    Trudy V. Murphy, Stephen M. Feinstone, Beth P. Bell

    15 Hepatitis B vaccines 205

    Pierre Van Damme, John Ward, Daniel Shouval, Steven Wiersma, Alessandro Zanetti

    16 Human papillomavirus vaccines 235

    John T. Schiller, Douglas R. Lowy, Lauri E. Markowitz

    17 Inactivated influenza vaccines 257

    Anthony E. Fiore, Carolyn B. Bridges, Jacqueline M. Katz, Nancy J. Cox

    18 Influenza vaccine-live 294

    Catherine J. Luke, Seema S. Lakdawala, Kanta Subbarao

    19 Japanese encephalitis vaccines 312

    Scott B. Halstead, Julie Jacobson, Katrin Dubischar-Kastner

    20 Measles vaccines 352

    Peter M. Strebel, Mark J. Papania, Amy Parker Fiebelkorn, Neal A. Halsey

    21 Meningococcal vaccines 388

    Dan M. Granoff, Stephen Pelton, Lee H. Harrison

    22 Mumps vaccine 419

    Steven A. Rubin, Stanley A. Plotkin

    23 Pertussis vaccines . 447

    Kathryn M. Edwards, Michael D. Decker

    24 Plague vaccines 493

    E. Diane Williamson, Petra C. F. Oyston

    25 Pneumococcal conjugate vaccine and pneumococcal common protein vaccines 504

    Keith P. Klugman, Steven Black, Ron Dagan, Richard Malley, Cynthia G. Whitney

    26 Pneumococcal polysaccharide vaccines 542

    Lisa A. Jackson

    27 Poliovirus vaccine-inactivated . 573

    Emmanuel Vidor, Stanley A. Plotkin

    28 Poliovirus vaccine-live 598

    Roland W. Sutter, Olen M. Kew, Stephen L. Cochi, R. Bruce Aylward

    29 Rabies vaccines .646

    Charles E. Rupprecht, Stanley A. Plotkin

    30 Rotavirus vaccines . 669

    H. Fred Clark, Paul A. Offit, Umesh D. Parashar

    31 Rubella vaccine 688

    Susan E. Reef, Stanley A. Plotkin

    32 Smallpox and vaccinia 718

    Richard B. Kennedy, J. Michael Lane, Donald A. Henderson, Gregory A. Poland

    33 Tetanus toxoid 746

    Martha H. Roper, Steven G. F. Wassilak, Tejpratap S. P. Tiwari, Walter A. Orenstein

    34 Tick-borne encephalitis virus vaccines 773

    P. Noel Barrett, Daniel Portsmouth, Hartmut J. Ehrlich

    35 Tuberculosis vaccines 789

    Kim Connelly Smith, Ian M. Orme, Jeffrey R. Starke

    36 Typhoid fever vaccines 812

    Myron M. Levine

    37 Varicella vaccine 837

    Anne A. Gershon, Michiaki Takahashi, Jane F. Seward

    38 Yellow fever vaccine 870

    Thomas P. Monath, Mark Gershman, J. Erin Staples, Alan D. T. Barrett

    39 Zoster vaccine 969

    Myron J. Levin

    40 Combination vaccines 981

    Michael D. Decker, Kathryn M. Edwards, Hugues H. Bogaerts

    SECTION 3: Vaccines in development and new vaccine strategies

    41 Biodefense and special pathogen vaccines 1008

    Phillip R. Pittman, Stanley A. Plotkin

    42 Therapeutic cancer vaccines 1018

    Neil L. Berinstein, Jeffrey A. Berinstein

    43 Cytomegalovirus vaccines 1032

    Mark R. Schleiss, Stanley A. Plotkin

    44 Dengue vaccines 1042

    Scott B. Halstead, Stephen J. Thomas

    45 Diarrhea caused by bacteria 1052

    James P. Nataro, Eileen M. Barry

    46 Ebola vaccine 1060

    Nancy J. Sullivan, Hugues F. Fausther-Bovendo, Gary J. Nabel

    47 Epstein-Barr virus vaccines 1068

    Viviana P. Lutzky, Denis J. Moss

    48 Hepatitis C vaccines 1074

    Sergio Abrignani, Eva Reali, Michael Houghton, Raffaele De Francesco

    49 Hepatitis E vaccines 1085

    Robert H. Purcell, Suzanne U. Emerson

    50 Herpes simplex virus vaccines 1090

    Lawrence R. Stanberry, Robert B. Belshe

    51 Human immunodeficiency virus vaccines 1097

    Marc P. Girard, Wayne C. Koff

    52 Lyme disease vaccines 1122

    Allen C. Steere, Ian Livey

    53 Malaria vaccines 1133

    W. Ripley Ballou, Joe Cohen

    54 Noninfectious disease vaccines 1138

    Philippe Saudan, Martin F. Bachmann

    55 Respiratory syncytial virus and parainfluenza virus vaccines 1146

    Ruth A. Karron

    56 Parasitic disease vaccines 1154

    Peter J. Hotez, Jeffrey M. Bethony

    57 Staphylococcus aureus vaccines 1161

    Robert S. Daum

    58 Streptococcus group A vaccines 1169

    Karen L. Kotloff

    59 Streptococcus group B vaccines 1176

    C. Mary Healy, Carol J. Baker

    60 Technologies for making new vaccines 1182

    Ronald W. Ellis, Rino Rappuoli, Sohail Ahmed

    61 Alternative vaccine delivery methods 1200

    Bruce G. Weniger, Mark J. Papania

    62 The development of gene-based vectors for immunization 1232

    David B. Weiner, Gary J. Nabel

    SECTION 4: Vaccination of special groups

    63 Vaccination of immunocompromised hosts 1243

    Per Ljungman

    64 Vaccination of human immunodeficiency virus-infected persons 1257

    William J. Moss, Catherine G. Sutcliffe, Neal A. Halsey

    65 Vaccines for international travel 1270

    Elizabeth D. Barnett, Phyllis E. Kozarsky, Robert Steffen

    66 Vaccines for health care personnel 1290

    David J. Weber, William A. Rutala

    SECTION 5: Public health and regulatory issues

    67 Immunization in the United States 1310

    Lance E. Rodewald, Walter A. Orenstein, Alan R. Hinman, Anne Schuchat

    68 Immunization in Europe . 1334

    David M. Salisbury, Rebecca M. Martin, Pierre Van Damme, Pier Luigi Lopalco

    69 Immunization in the Asia-Pacific region 1353

    Theodore F. Tsai, Hans Bock, Zhi Yi Xu

    70 Immunization in developing countries 1369

    Violaine Mitchell, Vance J. Dietz, Jean Marie Okwo-Bele, Felicity T. Cutts

    71 Community immunity 1395

    Paul E. M. Fine, Kim Mulholland

    72 Economic analyses of vaccine policies 1413

    Mark A. Miller, Alan R. Hinman

    73 Regulation and testing of vaccines 1427

    Norman W. Baylor, Valerie B. Marshall

    74 Regulation of vaccines in Europe 1447

    Falk Ehmann, Xavier Kurz, Marco Cavaleri, Peter R. Arlett

    75 Regulation of vaccines in developing countries 1454

    Lahouari Belgharbi, Nora Dellepiane, David J. Wood

    76 Vaccine safety 1464

    Paul A. Offit, Frank DeStefano

    77 Legal issues . 1481

    Geoffrey Evans, Emily Marcus Levine, Anna L. Jacobs

    78 Ethics 1508

    Arthur L. Caplan, Jason L. Schwartz

    Appendix 1514

    Deborah L. Wexler, Teresa A. Anderson, Mary R. Quirk

    Index .1521


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